KEGG   PATHWAY: sgm00630
Entry
sgm00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces aurantiacus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sgm00630  Glyoxylate and dicarboxylate metabolism
sgm00630

Module
sgm_M00621  Glycine cleavage system [PATH:sgm00630]
sgm_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgm00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces aurantiacus [GN:sgm]
Gene
GCM10017557_45490  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
GCM10017557_15740  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
GCM10017557_14950  aceB; malate synthase [KO:K01638] [EC:2.3.3.9]
GCM10017557_30840  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GCM10017557_36700  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
GCM10017557_53750  citrate synthase [KO:K01647] [EC:2.3.3.1]
GCM10017557_20750  citrate synthase [KO:K01647] [EC:2.3.3.1]
GCM10017557_20760  citrate synthase [KO:K01647] [EC:2.3.3.1]
GCM10017557_18490  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
GCM10017557_25210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GCM10017557_32010  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GCM10017557_58220  fadA5; steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
GCM10017557_61940  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GCM10017557_76150  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GCM10017557_11770  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GCM10017557_73930  phbB; beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
GCM10017557_25220  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GCM10017557_14290  protein meaA [KO:K14447] [EC:5.4.99.63]
GCM10017557_29670  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
GCM10017557_29610  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
GCM10017557_29620  hypothetical protein [KO:K27095]
GCM10017557_05050  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GCM10017557_05060  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GCM10017557_51540  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
GCM10017557_26910  katA; catalase [KO:K03781] [EC:1.11.1.6]
GCM10017557_76440  katA; catalase [KO:K03781] [EC:1.11.1.6]
GCM10017557_15140  catalase [KO:K03781] [EC:1.11.1.6]
GCM10017557_37440  hydrolase [KO:K01091] [EC:3.1.3.18]
GCM10017557_38690  hydrolase [KO:K01091] [EC:3.1.3.18]
GCM10017557_59690  type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GCM10017557_59950  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GCM10017557_60030  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GCM10017557_67080  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GCM10017557_02460  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GCM10017557_19890  hypothetical protein [KO:K01915] [EC:6.3.1.2]
GCM10017557_24140  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GCM10017557_25540  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GCM10017557_30760  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GCM10017557_20530  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GCM10017557_69540  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
GCM10017557_24120  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
GCM10017557_60220  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GCM10017557_24130  gcvH; glycine cleavage system H protein [KO:K02437]
GCM10017557_15710  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
GCM10017557_10270  hypothetical protein [KO:K01816] [EC:5.3.1.22]
GCM10017557_15690  putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
GCM10017557_71580  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GCM10017557_15700  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GCM10017557_14410  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GCM10017557_04410  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GCM10017557_58680  ketohydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GCM10017557_26170  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
GCM10017557_74690  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GCM10017557_74700  ferredoxin [KO:K00124]
GCM10017557_65940  fdoI; formate dehydrogenase subunit gamma [KO:K00127]
GCM10017557_02320  cyclase [KO:K07130] [EC:3.5.1.9]
GCM10017557_36570  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GCM10017557_13220  frc; formyl-CoA:oxalate CoA-transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sgm00010  Glycolysis / Gluconeogenesis
sgm00020  Citrate cycle (TCA cycle)
sgm00030  Pentose phosphate pathway
sgm00053  Ascorbate and aldarate metabolism
sgm00071  Fatty acid degradation
sgm00230  Purine metabolism
sgm00250  Alanine, aspartate and glutamate metabolism
sgm00260  Glycine, serine and threonine metabolism
sgm00620  Pyruvate metabolism
sgm00710  Carbon fixation by Calvin cycle
sgm00750  Vitamin B6 metabolism
sgm00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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