KEGG   PATHWAY: sgz00630
Entry
sgz00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces globosus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sgz00630  Glyoxylate and dicarboxylate metabolism
sgz00630

Module
sgz_M00012  Glyoxylate cycle [PATH:sgz00630]
sgz_M00621  Glycine cleavage system [PATH:sgz00630]
sgz_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgz00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces globosus [GN:sgz]
Gene
C0216_11530  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
C0216_01540  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C0216_09560  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
C0216_13065  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C0216_09655  malate synthase A [KO:K01638] [EC:2.3.3.9]
C0216_11535  malate synthase A [KO:K01638] [EC:2.3.3.9]
C0216_03430  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
C0216_26045  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
C0216_28445  citrate synthase [KO:K01647] [EC:2.3.3.1]
C0216_07790  citrate synthase [KO:K01647] [EC:2.3.3.1]
C0216_07795  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
C0216_08850  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
C0216_23150  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C0216_24625  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
C0216_27275  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C0216_05800  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C0216_10565  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C0216_18540  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
C0216_05795  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
C0216_10220  protein meaA [KO:K14447] [EC:5.4.99.63]
C0216_03805  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
C0216_03835  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
C0216_03830  acyl-CoA carboxylase subunit epsilon [KO:K27095]
C0216_08340  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C0216_08345  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C0216_03580  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
C0216_26650  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
C0216_04955  catalase [KO:K03781] [EC:1.11.1.6]
C0216_09595  catalase [KO:K03781] [EC:1.11.1.6]
C0216_14695  catalase HPII [KO:K03781] [EC:1.11.1.6]
C0216_28665  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
C0216_23975  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C0216_24060  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C0216_24310  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C0216_21475  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C0216_03470  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C0216_05645  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C0216_06150  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C0216_20295  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
C0216_06160  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
C0216_23935  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C0216_06155  gcvH; glycine cleavage system protein GcvH [KO:K02437]
C0216_09575  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
C0216_09605  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
C0216_09600  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
C0216_10170  glycerate kinase [KO:K00865] [EC:2.7.1.165]
C0216_05395  kgd; multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
C0216_28375  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sgz00010  Glycolysis / Gluconeogenesis
sgz00020  Citrate cycle (TCA cycle)
sgz00030  Pentose phosphate pathway
sgz00053  Ascorbate and aldarate metabolism
sgz00071  Fatty acid degradation
sgz00230  Purine metabolism
sgz00250  Alanine, aspartate and glutamate metabolism
sgz00260  Glycine, serine and threonine metabolism
sgz00620  Pyruvate metabolism
sgz00710  Carbon fixation by Calvin cycle
sgz00750  Vitamin B6 metabolism
sgz00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system