KEGG   PATHWAY: sgz00230
Entry
sgz00230                    Pathway                                
Name
Purine metabolism - Streptomyces globosus
Class
Metabolism; Nucleotide metabolism
Pathway map
sgz00230  Purine metabolism
sgz00230

Module
sgz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sgz00230]
sgz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sgz00230]
sgz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sgz00230]
sgz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sgz00230]
sgz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sgz00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces globosus [GN:sgz]
Gene
C0216_17700  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
C0216_27455  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
C0216_29665  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
C0216_29740  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
C0216_03405  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
C0216_29680  phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
C0216_29690  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
C0216_29685  phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
C0216_29660  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
C0216_27190  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
C0216_27185  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
C0216_29725  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
C0216_19720  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
C0216_03410  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
C0216_20960  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
C0216_29220  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
C0216_14280  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
C0216_26405  TIGR01457 family HAD-type hydrolase [KO:K02566] [EC:3.1.3.5]
C0216_03765  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
C0216_23440  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
C0216_17665  pyrimidine-specific ribonucleoside hydrolase RihA [KO:K25589] [EC:3.2.2.2 3.2.2.3]
C0216_01745  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
C0216_03230  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
C0216_03235  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
C0216_25530  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
C0216_26535  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
C0216_03280  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
C0216_20720  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
C0216_31245  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
C0216_20785  guanylate kinase [KO:K00942] [EC:2.7.4.8]
C0216_05035  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
C0216_07510  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
C0216_05030  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
C0216_25065  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
C0216_07460  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
C0216_20955  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
C0216_27330  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
C0216_02015  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
C0216_03845  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
C0216_01270  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
C0216_23815  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
C0216_02770  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
C0216_03660  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
C0216_15265  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
C0216_23075  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
C0216_03025  adenylate kinase [KO:K00939] [EC:2.7.4.3]
C0216_08645  adenylate kinase [KO:K00939] [EC:2.7.4.3]
C0216_21040  HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
C0216_09360  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
C0216_09350  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
C0216_09355  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
C0216_00835  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
C0216_09630  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
C0216_09625  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
C0216_03560  Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
C0216_09620  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
C0216_09700  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
C0216_31680  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
C0216_09705  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
C0216_06415  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
C0216_19655  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
C0216_19660  urease subunit beta [KO:K01429] [EC:3.5.1.5]
C0216_19665  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
C0216_06410  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sgz00030  Pentose phosphate pathway
sgz00220  Arginine biosynthesis
sgz00250  Alanine, aspartate and glutamate metabolism
sgz00260  Glycine, serine and threonine metabolism
sgz00340  Histidine metabolism
sgz00630  Glyoxylate and dicarboxylate metabolism
sgz00730  Thiamine metabolism
sgz00740  Riboflavin metabolism
sgz00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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