KEGG   PATHWAY: snv00230
Entry
snv00230                    Pathway                                
Name
Purine metabolism - Streptococcus pneumoniae INV200 (serotype 14)
Class
Metabolism; Nucleotide metabolism
Pathway map
snv00230  Purine metabolism
snv00230

Module
snv_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:snv00230]
snv_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:snv00230]
snv_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:snv00230]
snv_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:snv00230]
snv_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:snv00230]
Other DBs
GO: 0006163 0042278
Organism
Streptococcus pneumoniae INV200 (serotype 14) [GN:snv]
Gene
SPNINV200_09090  putative ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SPNINV200_07290  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SPNINV200_13340  pgmA; putative phosphomannomutase [KO:K01835] [EC:5.4.2.2]
SPNINV200_00280  prsA1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
SPNINV200_11100  prsA2; putative ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
SPNINV200_00460  purF; putative amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
SPNINV200_00510  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
SPNINV200_00480  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SPNINV200_00450  putative phosphoribosylformylglycinamidine synthase protein [KO:K01952] [EC:6.3.5.3]
SPNINV200_00470  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SPNINV200_00530  purK; putative phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
SPNINV200_00520  purE; putative phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
SPNINV200_00440  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SPNINV200_00550  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SPNINV200_00500  purH; bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SPNINV200_14140  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SPNINV200_07310  punA; putative purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
SPNINV200_07330  deoD; putative purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SPNINV200_00120  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SPNINV200_20370  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SPNINV200_17710  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SPNINV200_16990  HAM1 protein homolog [KO:K01519] [EC:3.6.1.66]
SPNINV200_16670  xpt; putative xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
SPNINV200_12870  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
SPNINV200_09870  GMP reductase [KO:K00364] [EC:1.7.1.7]
SPNINV200_15610  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SPNINV200_10500  putative ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
SPNINV200_10490  putative ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
SPNINV200_01860  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SPNINV200_14690  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SPNINV200_11080  conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
SPNINV200_00190  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SPNINV200_02130  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SPNINV200_19610  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
snv00030  Pentose phosphate pathway
snv00220  Arginine biosynthesis
snv00250  Alanine, aspartate and glutamate metabolism
snv00260  Glycine, serine and threonine metabolism
snv00630  Glyoxylate and dicarboxylate metabolism
snv00730  Thiamine metabolism
snv00740  Riboflavin metabolism
snv00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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