KEGG   PATHWAY: spap00230
Entry
spap00230                   Pathway                                
Name
Purine metabolism - Sphingomonas alpina
Class
Metabolism; Nucleotide metabolism
Pathway map
spap00230  Purine metabolism
spap00230

Module
spap_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:spap00230]
spap_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:spap00230]
spap_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:spap00230]
spap_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:spap00230]
spap_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:spap00230]
Other DBs
GO: 0006163 0042278
Organism
Sphingomonas alpina [GN:spap]
Gene
H3Z74_19430  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
H3Z74_20380  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
H3Z74_09630  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
H3Z74_22660  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
H3Z74_08960  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
H3Z74_03385  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
H3Z74_05500  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
H3Z74_05495  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
H3Z74_08965  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
H3Z74_22730  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
H3Z74_22735  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
H3Z74_01675  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
H3Z74_05510  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
H3Z74_14955  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
H3Z74_20970  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
H3Z74_14640  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
H3Z74_08145  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
H3Z74_22565  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
H3Z74_08940  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
H3Z74_15035  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
H3Z74_14015  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
H3Z74_16985  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
H3Z74_14010  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
H3Z74_16980  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
H3Z74_14005  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
H3Z74_16975  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
H3Z74_03220  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
H3Z74_02010  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
H3Z74_15130  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
H3Z74_15165  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
H3Z74_04770  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
H3Z74_21590  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
H3Z74_08985  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
H3Z74_21600  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
H3Z74_07845  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
H3Z74_23070  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
H3Z74_07690  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
H3Z74_22550  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
H3Z74_14245  adenylate kinase [KO:K00939] [EC:2.7.4.3]
H3Z74_09110  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
H3Z74_07915  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
H3Z74_09770  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
H3Z74_09765  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
spap00030  Pentose phosphate pathway
spap00220  Arginine biosynthesis
spap00250  Alanine, aspartate and glutamate metabolism
spap00260  Glycine, serine and threonine metabolism
spap00340  Histidine metabolism
spap00630  Glyoxylate and dicarboxylate metabolism
spap00730  Thiamine metabolism
spap00740  Riboflavin metabolism
spap00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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