KEGG   PATHWAY: strn00230
Entry
strn00230                   Pathway                                
Name
Purine metabolism - Streptococcus sp. NPS 308
Class
Metabolism; Nucleotide metabolism
Pathway map
strn00230  Purine metabolism
strn00230

Module
strn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:strn00230]
strn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:strn00230]
strn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:strn00230]
strn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:strn00230]
strn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:strn00230]
Other DBs
GO: 0006163 0042278
Organism
Streptococcus sp. NPS 308 [GN:strn]
Gene
SNAG_0012  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SNAG_0022  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SNAG_0083  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SNAG_0097  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SNAG_0098  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
SNAG_0099  purF; amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
SNAG_0100  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SNAG_0101  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SNAG_0103  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SNAG_0104  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
SNAG_0105  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
SNAG_0106  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
SNAG_0108  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SNAG_0375  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
SNAG_0471  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
SNAG_0899  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
SNAG_0949  prs2; ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
SNAG_0951  yjbM; GTP pyrophosphokinase YjbM [KO:K07816] [EC:2.7.6.5]
SNAG_0961  pgcA; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SNAG_1081  nrdE2; ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
SNAG_1083  nrdF; ribonucleoside-diphosphate reductase 2 subunit beta [KO:K00526] [EC:1.17.4.1]
SNAG_1109  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SNAG_1132  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
SNAG_1186  deoD_2; purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
SNAG_1187  punA; purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
SNAG_1189  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SNAG_1424  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SNAG_1475  relA; bifunctional (p)ppGpp synthase/hydrolase RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SNAG_1511  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SNAG_1658  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SNAG_1687  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SNAG_1715  nrdD_2; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SNAG_1804  arcC1; carbamate kinase 1 [KO:K00926] [EC:2.7.2.2]
SNAG_1811  yfkN; trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
SNAG_1889  guaB_2; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
strn00030  Pentose phosphate pathway
strn00220  Arginine biosynthesis
strn00250  Alanine, aspartate and glutamate metabolism
strn00260  Glycine, serine and threonine metabolism
strn00630  Glyoxylate and dicarboxylate metabolism
strn00730  Thiamine metabolism
strn00740  Riboflavin metabolism
strn00790  Folate biosynthesis
KO pathway
ko00230   

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