KEGG   PATHWAY: tib00230
Entry
tib00230                    Pathway                                
Name
Purine metabolism - Thiomicrorhabdus immobilis
Class
Metabolism; Nucleotide metabolism
Pathway map
tib00230  Purine metabolism
tib00230

Module
tib_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tib00230]
tib_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tib00230]
tib_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tib00230]
tib_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tib00230]
tib_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tib00230]
Other DBs
GO: 0006163 0042278
Organism
Thiomicrorhabdus immobilis [GN:tib]
Gene
THMIRHAM_01100  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
THMIRHAM_03150  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
THMIRHAM_04430  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
THMIRHAM_05050  xanA; phosphohexose mutases [KO:K15778] [EC:5.4.2.8 5.4.2.2]
THMIRHAM_05420  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
THMIRHAM_05440  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
THMIRHAM_05460  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
THMIRHAM_06350  apaH; bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
THMIRHAM_06800  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
THMIRHAM_06810  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
THMIRHAM_10200  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
THMIRHAM_10800  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
THMIRHAM_11470  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
THMIRHAM_11610  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
THMIRHAM_11980  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
THMIRHAM_12480  [KO:K01768] [EC:4.6.1.1]
THMIRHAM_13300  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
THMIRHAM_14140  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
THMIRHAM_14300  [KO:K01129] [EC:3.1.5.1]
THMIRHAM_14570  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
THMIRHAM_14580  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
THMIRHAM_15110  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
THMIRHAM_15370  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
THMIRHAM_15990  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
THMIRHAM_17800  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
THMIRHAM_17820  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
THMIRHAM_18320  nrdA; ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
THMIRHAM_18350  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
THMIRHAM_18360  [KO:K20881] [EC:3.1.3.-]
THMIRHAM_18420  nrdB; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
THMIRHAM_18820  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
THMIRHAM_18830  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
THMIRHAM_19430  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
THMIRHAM_19530  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
THMIRHAM_20460  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
THMIRHAM_20790  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
THMIRHAM_20840  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
THMIRHAM_21290  [KO:K22602] [EC:3.5.1.126]
THMIRHAM_21520  [KO:K01519] [EC:3.6.1.66]
THMIRHAM_21880  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
THMIRHAM_22000  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
THMIRHAM_22060  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tib00030  Pentose phosphate pathway
tib00220  Arginine biosynthesis
tib00250  Alanine, aspartate and glutamate metabolism
tib00260  Glycine, serine and threonine metabolism
tib00340  Histidine metabolism
tib00630  Glyoxylate and dicarboxylate metabolism
tib00730  Thiamine metabolism
tib00740  Riboflavin metabolism
tib00790  Folate biosynthesis
KO pathway
ko00230   

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