KEGG   PATHWAY: tlo00230
Entry
tlo00230                    Pathway                                
Name
Purine metabolism - Thiothrix litoralis
Class
Metabolism; Nucleotide metabolism
Pathway map
tlo00230  Purine metabolism
tlo00230

Module
tlo_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:tlo00230]
tlo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tlo00230]
tlo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tlo00230]
tlo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tlo00230]
tlo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tlo00230]
tlo_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:tlo00230]
tlo_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:tlo00230]
Other DBs
GO: 0006163 0042278
Organism
Thiothrix litoralis [GN:tlo]
Gene
J9253_01135  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
J9253_02015  [KO:K01835] [EC:5.4.2.2]
J9253_02235  [KO:K00948] [EC:2.7.6.1]
J9253_02445  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
J9253_02965  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
J9253_03370  [KO:K00760] [EC:2.4.2.8]
J9253_04230  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
J9253_04235  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
J9253_04375  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
J9253_04845  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
J9253_05665  [KO:K01939] [EC:6.3.4.4]
J9253_09530  [KO:K01129] [EC:3.1.5.1]
J9253_09660  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
J9253_09665  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
J9253_09670  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
J9253_10090  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
J9253_11395  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
J9253_11510  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
J9253_12820  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
J9253_12825  [KO:K01429] [EC:3.5.1.5]
J9253_12830  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
J9253_12880  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
J9253_12885  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
J9253_12890  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
J9253_12895  [KO:K01483] [EC:4.3.2.3]
J9253_12900  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
J9253_12905  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
J9253_12910  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
J9253_12925  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
J9253_13125  [KO:K01768] [EC:4.6.1.1]
J9253_13970  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
J9253_14305  [KO:K01525] [EC:3.6.1.41]
J9253_14355  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
J9253_14545  [KO:K03651] [EC:3.1.4.53]
J9253_14915  [KO:K00526] [EC:1.17.4.1]
J9253_14935  [KO:K00525] [EC:1.17.4.1]
J9253_14990  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
J9253_15000  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
J9253_15380  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
J9253_15390  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
J9253_15695  [KO:K00958] [EC:2.7.7.4]
J9253_16655  [KO:K01589] [EC:6.3.4.18]
J9253_16660  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
J9253_16665  [KO:K01923] [EC:6.3.2.6]
J9253_16845  [KO:K00951] [EC:2.7.6.5]
J9253_17370  [KO:K00958] [EC:2.7.7.4]
J9253_17710  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
J9253_18115  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
J9253_18130  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
J9253_18530  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
J9253_18535  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
J9253_18655  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
J9253_18715  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
J9253_18945  [KO:K01768] [EC:4.6.1.1]
J9253_19420  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
J9253_20530  [KO:K21636] [EC:1.1.98.6]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tlo00030  Pentose phosphate pathway
tlo00220  Arginine biosynthesis
tlo00250  Alanine, aspartate and glutamate metabolism
tlo00260  Glycine, serine and threonine metabolism
tlo00340  Histidine metabolism
tlo00630  Glyoxylate and dicarboxylate metabolism
tlo00730  Thiamine metabolism
tlo00740  Riboflavin metabolism
tlo00790  Folate biosynthesis
KO pathway
ko00230   

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