Cilium and Associated Proteins

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 Primary cilia and associated proteins
   BBSome
   BBS-CCT complex
   Intraflagellar transport (IFT) complex A
   Intraflagellar transport (IFT) complex B1
   Intraflagellar transport (IFT) complex B2
   Dynein and associated proteins
   Kinesin-2 and associated proteins
   MKS complex
   Nephronophthisis-related proteins
     K19657  NPHP1; nephrocystin-1
     K19626  INVS; inversin
     K19360  NPHP3; nephrocystin-3
     K16478  NPHP4; nephrocystin-4
     K16774  IQCB1, NPHP5; IQ calmodulin-binding motif-containing protein 1
     K16533  CEP290, NPHP6; centrosomal protein CEP290
     K09233  GLIS2; zinc finger protein GLIS2
     K23405  DCDC2; doublecortin domain-containing protein 2
     K22870  ZNF423; zinc finger protein 423
   Ciliogenesis and planar polarity effectors (CPLANE) complex
   EVC complex
   USH complex and associated proteins
   Tubulin polyglutamylase and associated proteins
   Other primary cilia associated proteins
     K16741  ALMS1; alstrom syndrome protein 1
     K21415  ANKS6; ankyrin repeat and SAM domain-containing protein 6
     K16742  ARL2BP, BART; ADP-ribosylation factor-like protein 2-binding protein
     K07944  ARL3; ADP-ribosylation factor-like protein 3
     K07962  ARL13B, ARL2L1; ADP-ribosylation factor-like protein 13B
     K22864  ARMC9; LisH domain-containing protein ARMC9
     K16540  AZI1, CEP131; 5-azacytidine-induced protein 1
     K23402  CBY1; protein chibby 1
     K25390  CETN4; centrin-4
     K25391  DBN1; drebrin
     K16534  DISC1; disrupted in schizophrenia 1 protein
     K16470  DZIP1; zinc finger protein DZIP1
     K23868  FAM92; protein FAM92
     K24653  FAM149; primary cilium assembly protein FAM149
     K16772  FAM161; protein FAM161
     K16535  FOPNL, FOR20; lisH domain-containing protein FOPNL
     K08828  ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
     K08817  CDK20, CCRK; cyclin-dependent kinase 20 [EC:2.7.11.22]
     K28444  TBC1D32, BROMI; TBC1 domain family member 32
     K08857  NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
     K20877  NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
     K16480  OFD1; oral-facial-digital syndrome 1 protein
     K16537  PCM1; pericentriolar material 1 protein
     K25393  PIFO; protein pitchfork
     K26197  GPRASP2; G-protein coupled receptor-associated sorting protein 2
     K19865  PKHD1; fibrocystin
     K16482  POC1; centriolar protein POC1
     K18040  PTPN23; tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]
     K16484  RTTN; rotatin
     K24869  SCAPER; S phase cyclin A-associated protein in the endoplasmic reticulum
     K22938  SDCCAG3, ENTR1; serologically defined colon cancer antigen 3
     K16488  SDCCAG8; serologically defined colon cancer antigen 8
     K06229  SUFU; suppressor of fused
     K23404  TAPT1; transmembrane anterior posterior transformation protein 1
     K25394  TMEM80; transmembrane protein 80
     K22867  TMEM138; transmembrane protein 138
     K24886  TOGARAM; TOG array regulator of axonemal microtubules protein
     K16801  CEP19; centrosomal protein CEP19
     K16455  CEP41, TSGA14; centrosomal protein CEP41
     K16765  CEP78; centrosomal protein CEP78
     K16458  CEP104; centrosomal protein CEP104
     K16771  CSPP1; centrosome and spindle pole-associated protein 1
     K25395  CFAP36; cilia- and flagella-associated protein 36
     K25396  CFAP126; protein Flattop
     K28375  CFAP263; cilia- and flagella-associated protein 263
     K23456  CFAP410, C21ORF2; cilla- and flagella-associated protein
     K25392  CCDC88A; girdin
     K27917  CCDC13; coiled-coil domain-containing protein 13
     K25397  CCDC66; coiled-coil domain-containing protein 66
     K25398  CCDC68; coiled-coil domain containing protein 68
     K25399  CCDC120; coiled-coil domain containing protein 120
     K16754  CEP83, CCDC41; centrosomal protein CEP83
     K16543  CEP89; centrosomal protein CEP89
     K16462  CEP164; centrosomal protein CEP164
     K16471  FBF1, ALB; Fas-binding factor 1
     K25400  SCLT1; sodium channel and clathrin linker 1
     K16453  CCP110, CEP110; centrosomal protein CEP110
     K16717  CEP97; centrosomal protein CEP97
     K27678  ENKD1; enkurin domain-containing protein 1
     K16461  CEP135, CEP4; centrosomal protein CEP135
     K16751  C2CD3; C2 domain-containing protein 3
     K16469  CROCC; rootletin
     K25226  C8ORF37; protein C8orf37
     K24828  LCA5; lebercilin
     K25401  LRRC45; leucine-rich repeat-containing protein 45
     K25402  CYS1; cystin-1
     K04985  PKD1; polycystin 1
     K04986  PKD2; polycystin 2
     K04987  PKD1L1; polycystin 1L1
     K04990  PKD2L1; polycystin 2L1
     K07931  RABL2; Rab-like protein 2
     K20173  RILPL1; RILP-like protein 1
     K25403  RILPL2; RILP-like protein 2
     K17343  PRPH2, TSPAN22; peripherin-2
     K24165  PCARE; photoreceptor cilium actin regulator
     K19637  PRCD; progressive rod-cone degeneration protein
     K25404  RD3; protein RD3
     K04254  RGR; retinal G protein coupled receptor
     K13765  RGS9; regulator of G-protein signaling 9
     K25405  RGS9BP; regulator of G-protein signaling 9-binding protein
     K17344  ROM1, TSPAN23; rod outer segment membrane protein 1
     K19600  TUB, TULP; tubby and related proteins
     K19538  RP1; retinitis pigmentosa 1
     K18272  RP2; protein XRP2
     K19607  RPGR; X-linked retinitis pigmentosa GTPase regulator
     K16512  RPGRIP1; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
     K08829  MAK; male germ cell-associated kinase [EC:2.7.11.22]
     K10631  TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
     K16780  SSNA1; sjoegren syndrome nuclear autoantigen 1
     K22865  TALPID3, JBTS23; protein TALPID3
     K25138  ANKRD26; ankyrin repeat domain-containing protein 26
     K19685  TTC26, IFT56, DYF13; intraflagellar transport protein 56
     K24759  WDR90; WD repeat-containing protein 90
     K27918  BLTP2, HOB; bridge-like lipid transfer protein family member 2
     K28284  KIAA1549; UPF0606 protein KIAA1549
 Motile cilia and associated proteins
 Other cilia and associated proteins
   Stereociliary proteins
     K24636  STRC; stereocilin
     K24047  ESPN; espin
     K08834  MYO3, DFNB30; myosin III [EC:2.7.11.1]
     K17277  EPS8; epidermal growth factor receptor kinase substrate 8
     K15837  GPSM2; G-protein signaling modulator 2
     K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
     K06499  CEACAM, CD66; carcinoembryonic antigen-related cell adhesion molecule
     K06087  CLDN; claudin
     K05025  CLIC5; chloride intracellular channel protein 5
     K00545  COMT, TOMT; catechol O-methyltransferase [EC:2.1.1.6]
     K25700  CTHRC1; collagen triple helix repeat-containing protein 1
     K23538  ELMOD; ELMO domain-containing protein
     K17479  GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
     K24294  GRXCR2; glutaredoxin domain-contaning cysteine-rich protein 2
     K15010  HOMER; homer
     K23893  LHFPL; LHFPL tetraspan subfamily member protein
     K24822  LOXHD1; lipoxygenase homology domain-containing protein 1
     K25701  MORN4; MORN repeat-containing protein 4
     K25030  OTOG, OTOGL; otogelin
     K16910  PTPRQ; receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]
     K24818  RIPOR, FAM65; Rho family-interacting cell polarization regulator
     K21841  TBC1D24; TBC1 domain family member 24
     K18273  TECTA; alpha-tectorin
     K25702  TECTB; beta-tectorin
     K21988  TMC; transmembrane channel-like protein
     K08870  TWF; twinfilin
     K25703  VEZT; vezatin
     K24437  TSEAR; thrombospondin-type laminin G domain and EAR repeat-containing protein
     K25704  ZSWIM6; zinc finger SWIM domain-containing protein 6
     K27624  PKHD1L1; fibrocystin-L
     K27919  USP53; inactive ubiquitin carboxyl-terminal hydrolase 53
   Other cilium assembly proteins

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Last updated: June 23, 2026