KEGG   PATHWAY: onl04810
Entry
onl04810                    Pathway                                
Name
Regulation of actin cytoskeleton - Oreochromis niloticus (Nile tilapia)
Class
Cellular Processes; Cell motility
Pathway map
onl04810  Regulation of actin cytoskeleton
onl04810

Other DBs
GO: 0030036
Organism
Oreochromis niloticus (Nile tilapia) [GN:onl]
Gene
100691976  lpar1; lysophosphatidic acid receptor 1 [KO:K04289]
100693650  lysophosphatidic acid receptor 2 [KO:K04291]
100695639  lysophosphatidic acid receptor 1-A [KO:K04291]
100695280  stromal cell-derived factor 1 [KO:K10031]
100709445  stromal cell-derived factor 1 [KO:K10031]
100703262  cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
100693032  C-X-C chemokine receptor type 4 [KO:K04189]
100702313  prothrombin [KO:K01313] [EC:3.4.21.5]
100695510  proteinase-activated receptor 1-like isoform X1 [KO:K03914]
100695247  proteinase-activated receptor 1 [KO:K03914]
100702757  proteinase-activated receptor 1 [KO:K03914]
106096766  proteinase-activated receptor 1-like [KO:K03914]
100706519  proteinase-activated receptor 1 [KO:K03914]
100692120  ins; insulin [KO:K04526]
100704156  insulin [KO:K04526]
100706539  egf; pro-epidermal growth factor [KO:K04357]
100693787  putative fibroblast growth factor 1 isoform X1 [KO:K18496]
100705330  fgf1; fibroblast growth factor 1 isoform X1 [KO:K18496]
100696875  fgf2; fibroblast growth factor 2 [KO:K18497]
100690089  fgf22; fibroblast growth factor 22 [KO:K04358]
100696901  fgf20a; fibroblast growth factor 20a [KO:K04358]
100700557  fgf16; fibroblast growth factor 16 [KO:K04358]
100694765  fibroblast growth factor 18 isoform X1 [KO:K04358]
100708453  fibroblast growth factor 6 [KO:K04358]
100698613  fibroblast growth factor 8b [KO:K04358]
100707945  fibroblast growth factor 4-like [KO:K04358]
100704516  fibroblast growth factor 18 isoform X2 [KO:K04358]
100689794  fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
100711857  fgf10; fibroblast growth factor 10 [KO:K04358]
100695827  fgf5; fibroblast growth factor 5 [KO:K04358]
100700362  fibroblast growth factor 5 [KO:K04358]
100711879  fgf20b; fibroblast growth factor 20b [KO:K04358]
100700511  fgf7; fibroblast growth factor 7 [KO:K04358]
100705632  fgf3; LOW QUALITY PROTEIN: fibroblast growth factor 3 [KO:K04358]
100705897  fgf4; fibroblast growth factor 4 isoform X1 [KO:K04358]
100691488  fibroblast growth factor 8 isoform X1 [KO:K04358]
100698056  fgf6; fibroblast growth factor 6 isoform X2 [KO:K04358]
100706425  fgf19; fibroblast growth factor 19 [KO:K22603]
100703128  fibroblast growth factor 21 [KO:K22429]
100708188  fgf23; fibroblast growth factor 23 [KO:K22428]
102078062  fibroblast growth factor 23 isoform X1 [KO:K22428]
100690958  platelet-derived growth factor subunit A isoform X1 [KO:K04359]
100702821  pdgfa; platelet-derived growth factor subunit A [KO:K04359]
100712331  uncharacterized protein LOC100712331 [KO:K17386]
100700544  pdgfd; platelet-derived growth factor D isoform X2 [KO:K05450]
100707883  pdgfc; platelet-derived growth factor C [KO:K05450]
100711613  melanoma receptor tyrosine-protein kinase [KO:K04361] [EC:2.7.10.1]
106097625  epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
100695709  egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
100695445  epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
100698136  fgfr1a; fibroblast growth factor receptor 1a precursor [KO:K04362] [EC:2.7.10.1]
100707841  fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
102078731  tyrosine kinase receptor Cad96Ca [KO:K04362] [EC:2.7.10.1]
100708380  fibroblast growth factor receptor 1-A [KO:K04362] [EC:2.7.10.1]
100699731  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
100689850  fgfr3; fibroblast growth factor receptor 3 isoform X3 [KO:K05094] [EC:2.7.10.1]
100692465  fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
100692594  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
100695603  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
100709470  platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
100689834  fibronectin [KO:K05717]
100696180  fibronectin isoform X2 [KO:K05717]
100697706  itga1; integrin alpha-1 [KO:K06480]
100711318  itga2; integrin alpha-2 isoform X1 [KO:K06481]
100704409  integrin alpha-IIb isoform X1 [KO:K06476]
100712166  itga3; integrin alpha-3 isoform X2 [KO:K06482]
100705213  integrin alpha-3 isoform X1 [KO:K06482]
100693712  itga4; integrin alpha-4 [KO:K06483]
100696606  integrin alpha-5 isoform X1 [KO:K06484]
100711983  integrin alpha-5 [KO:K06484]
100704787  integrin alpha-6 [KO:K06485]
100690424  integrin alpha-6 isoform X1 [KO:K06485]
100696272  itga6; integrin alpha-6 isoform X1 [KO:K06485]
100693178  itga7; integrin alpha-7 isoform X1 [KO:K06583]
100691211  itga8; integrin alpha-8 [KO:K06584]
100704407  itga9; integrin alpha-9 [KO:K06585]
100708721  itga10; integrin alpha-10 isoform X2 [KO:K06586]
100691061  integrin alpha-11 [KO:K06587]
100690041  itga11; integrin alpha-11 [KO:K06587]
100697617  itgav; integrin alpha-V isoform X1 [KO:K06487]
100708169  integrin alpha-L [KO:K05718]
109202376  integrin alpha-L isoform X4 [KO:K05718]
100708437  integrin alpha-L isoform X3 [KO:K05718]
100709660  integrin alpha-M [KO:K06461]
102082286  integrin alpha-M isoform X1 [KO:K06461]
102080873  integrin alpha-M-like [KO:K06461]
100694924  integrin alpha-M [KO:K06461]
100695195  integrin alpha-M [KO:K06461]
100706709  integrin alpha-M [KO:K06461]
100708312  integrin alpha-M isoform X2 [KO:K06461]
100706614  integrin alpha-X [KO:K06461]
100707242  integrin alpha-M [KO:K06461]
100708582  integrin alpha-M [KO:K06461]
100708851  LOW QUALITY PROTEIN: integrin alpha-M [KO:K06461]
100709123  integrin alpha-M [KO:K06461]
100709934  integrin alpha-M [KO:K06461]
102081848  integrin alpha-M-like isoform X1 [KO:K06461]
106098356  integrin alpha-M [KO:K06461]
109203257  integrin alpha-M [KO:K06461]
100692535  integrin beta-1 [KO:K05719]
100703476  integrin beta-2 isoform X1 [KO:K06464]
109194284  integrin beta-2 [KO:K06464]
100708604  itgb3; integrin beta-3 [KO:K06493]
100699105  integrin beta-3 isoform X1 [KO:K06493]
100691235  itgb4; integrin beta-4 isoform X1 [KO:K06525]
100693382  itgb5; integrin beta-5 [KO:K06588]
100695654  itgb6; integrin beta-6 isoform X1 [KO:K06589]
100695610  itgb8; integrin beta-8 isoform X1 [KO:K06591]
100705815  kininogen-1 isoform X1 [KO:K03898]
109195918  B2 bradykinin receptor-like [KO:K03916]
109195919  B2 bradykinin receptor-like [KO:K03916]
100690540  B2 bradykinin receptor [KO:K03916]
100690814  B2 bradykinin receptor-like [KO:K03916]
100689737  B2 bradykinin receptor [KO:K03916]
100690006  B2 bradykinin receptor-like [KO:K03916]
100691617  B2 bradykinin receptor [KO:K03916]
100691346  B2 bradykinin receptor [KO:K03916]
100691077  B1 bradykinin receptor-like isoform X1 [KO:K03916]
100534567  muscarinic receptor 4 subtype [KO:K04130]
100534441  chrm2a; muscarinic acetylcholine receptor M2a [KO:K04130]
100534440  chrm3a; cholinergic receptor, muscarinic 3a [KO:K04131]
100700872  muscarinic acetylcholine receptor M1 isoform X1 [KO:K04131]
100699420  muscarinic acetylcholine receptor M4 [KO:K04132]
100691419  muscarinic acetylcholine receptor M2 isoform X2 [KO:K04132]
100534442  chrm5a; muscarinic acetylcholine receptor M5a [KO:K04133]
100534444  chrm5; muscarinic acetylcholine receptor M5 [KO:K04133]
100703748  c5; complement C5 [KO:K03994]
100705566  c6; complement component C6 isoform X1 [KO:K03995]
100701281  complement component C7 [KO:K03996]
100697225  complement component C7 [KO:K03996]
100694264  c8a; complement component C8 alpha chain [KO:K03997]
100693988  c8b; complement component C8 beta chain precursor [KO:K03998]
100711827  c8g; complement component C8 gamma chain [KO:K03999]
100705609  c9; complement component C9 [KO:K04000]
100695956  gna12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346]
100701321  guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
100712037  guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
100700730  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
100698985  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
100711863  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04347]
109194285  fgd1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720]
100689713  FYVE, RhoGEF and PH domain-containing protein 3 isoform X3 [KO:K05722]
100692252  focal adhesion kinase 1 isoform X5 [KO:K05725] [EC:2.7.10.2]
100700494  ptk2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
100705076  bcar1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726]
100696389  adapter molecule crk [KO:K04438]
100705099  adapter molecule crk isoform X1 [KO:K04438]
100708521  crkl; crk-like protein [KO:K04438]
100711819  dock1; dedicator of cytokinesis protein 1 isoform X1 [KO:K13708]
100690332  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
100692677  proto-oncogene tyrosine-protein kinase Src isoform X4 [KO:K05704] [EC:2.7.10.2]
100701539  sos2; son of sevenless homolog 2 [KO:K03099]
100706444  sos1; LOW QUALITY PROTEIN: son of sevenless homolog 1 [KO:K03099]
100706358  hras; GTPase HRas [KO:K02833]
100703836  GTPase HRas [KO:K07827]
100694749  kras; GTPase KRas isoform X2 [KO:K07827]
100699786  ras-related protein R-Ras isoform X1 [KO:K07830]
100693950  rras2; ras-related protein R-Ras2 [KO:K07830]
100690274  mras; ras-related protein M-Ras [KO:K07831]
100704152  arhgef6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729]
100704479  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100707861  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100706609  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100705849  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
100691322  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
100693657  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
100710015  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100709733  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
100691647  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100708273  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
100690473  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X5 [KO:K02649]
100699613  vav1; proto-oncogene vav isoform X1 [KO:K05730]
100691909  guanine nucleotide exchange factor VAV3 isoform X3 [KO:K05730]
100707159  vav2; guanine nucleotide exchange factor VAV2 isoform X4 [KO:K05730]
100709469  vav3; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
100698758  T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
100694077  tiam1; T-lymphoma invasion and metastasis-inducing protein 1 [KO:K05731]
100698373  serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
100708231  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
100709219  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
100695699  mos; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
100694033  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
100708547  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
100697571  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
100697722  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
100701546  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
100707971  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100705233  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100692017  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100702193  RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100691860  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100690121  regulator of cell cycle RGCC [KO:K26108]
100696796  regulator of cell cycle RGCC [KO:K26108]
102081168  arhgef1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
100699405  arhgef12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
100710886  rho GTPase-activating protein 35 [KO:K05732]
100690580  arhgap35; rho GTPase-activating protein 35 [KO:K05732]
100694803  rho-related GTP-binding protein RhoA-D [KO:K04513]
100696538  rho-related GTP-binding protein RhoA-C [KO:K04513]
100710477  rho-related GTP-binding protein RhoA-B [KO:K04513]
100698785  rho-related GTP-binding protein RhoA-C [KO:K04513]
100707445  rho-related GTP-binding protein RhoA-B [KO:K04513]
100696401  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
106096418  ras-related C3 botulinum toxin substrate 1-like isoform X3 [KO:K04392]
100697553  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
100708583  rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
100696834  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
100708296  ras-related C3 botulinum toxin substrate 2 [KO:K07860]
100712409  rac3; LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 3 [KO:K07861]
100705444  cell division control protein 42 homolog isoform X3 [KO:K04393]
100705703  cell division control protein 42 homolog isoform X2 [KO:K04393]
106096466  cell division control protein 42 homolog isoform X1 [KO:K04393]
100712562  cell division control protein 42 homolog [KO:K04393]
100697482  cell division control protein 42 homolog isoform X2 [KO:K04393]
109196582  cell division control protein 42 homolog [KO:K04393]
100705174  cell division control protein 42 homolog isoform X1 [KO:K04393]
100691174  cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
100696557  cell division control protein 42 homolog [KO:K04393]
100698864  pak1; serine/threonine-protein kinase PAK 1 isoform X2 [KO:K04409] [EC:2.7.11.1]
100708502  pak2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
100710923  serine/threonine-protein kinase PAK 2 isoform X1 [KO:K04410] [EC:2.7.11.1]
100690197  serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
100708294  serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
100697856  pak5; serine/threonine-protein kinase PAK 5 isoform X2 [KO:K05736] [EC:2.7.11.1]
100706553  pak6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
100696183  serine/threonine-protein kinase PAK 6 isoform X3 [KO:K05735] [EC:2.7.11.1]
100696931  rho guanine nucleotide exchange factor 7 isoform X2 [KO:K13710]
100695420  arhgef7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710]
100708130  git1; ARF GTPase-activating protein GIT1 isoform X2 [KO:K05737]
100697034  rock1; LOW QUALITY PROTEIN: rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.1]
100709780  rock2; rho-associated protein kinase 2 isoform X3 [KO:K17388] [EC:2.7.11.1]
100701417  rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
100694458  myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
100704596  myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
100698528  mylk4; myosin light chain kinase family member 4 isoform X1 [KO:K00907] [EC:2.7.11.18]
100690170  myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
100704574  myosin light chain kinase 3 isoform X2 [KO:K00907] [EC:2.7.11.18]
100704504  myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
100692155  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100692170  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100691882  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
100706881  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
109196021  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
100689853  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
100691168  protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
100701481  ppp1r12a; protein phosphatase 1 regulatory subunit 12A isoform X3 [KO:K06270]
100701156  protein phosphatase 1 regulatory subunit 12B isoform X5 [KO:K12329]
109194150  ppp1r12c; protein phosphatase 1 regulatory subunit 12C isoform X2 [KO:K17457]
100699907  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
100690118  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
106098660  myosin regulatory light chain 2, atrial isoform [KO:K12754]
106098659  myosin regulatory light chain 2, atrial isoform [KO:K12754]
100697131  myosin regulatory light polypeptide 9 [KO:K12755]
100710463  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
100708845  myosin regulatory light polypeptide 9 [KO:K12757]
100702521  mylpf; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
100709026  myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
100690099  myosin-10 isoform X3 [KO:K10352]
100691292  myh11; myosin-11 isoform X1 [KO:K10352]
100699125  myosin-10 isoform X5 [KO:K10352]
100705764  myosin-9 isoform X1 [KO:K10352]
100707073  myh9; myosin-9 isoform X1 [KO:K10352]
100711292  LOW QUALITY PROTEIN: protein diaphanous homolog 1 [KO:K05740]
100712010  diaph2; protein diaphanous homolog 2 [KO:K05741]
109196493  Na(+)/H(+) exchanger beta-like isoform X2 [KO:K05742]
100705611  sodium/hydrogen exchanger 1 isoform X2 [KO:K05742]
100693255  Na(+)/H(+) exchanger beta [KO:K05742]
100711435  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X7 [KO:K00889] [EC:2.7.1.68]
100697221  pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
100701476  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
100711950  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
100707864  phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
100698290  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
100711288  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
100707852  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
100705399  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
100701287  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
100695781  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 [KO:K00921] [EC:2.7.1.150]
100693040  LIM domain kinase 1 isoform X1 [KO:K05743] [EC:2.7.11.1]
100704692  LIM domain kinase 1 isoform X3 [KO:K05743] [EC:2.7.11.1]
100704902  limk2; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
100693248  protein diaphanous homolog 3 isoform X2 [KO:K05745]
100691738  brain-specific angiogenesis inhibitor 1-associated protein 2 [KO:K05627]
100696811  brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627]
100711936  brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627]
100701304  enah; LOW QUALITY PROTEIN: protein enabled homolog [KO:K05746]
102076870  neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612]
100693780  LOW QUALITY PROTEIN: neural Wiskott-Aldrich syndrome protein [KO:K23612]
100711937  LOW QUALITY PROTEIN: neural Wiskott-Aldrich syndrome protein [KO:K23612]
100697143  wasf2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
100704422  cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
100711402  cyfip1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
100692363  nckap1l; nck-associated protein 1-like [KO:K05750]
100692943  nckap1; nck-associated protein 1 isoform X3 [KO:K05750]
100698321  abi2; LOW QUALITY PROTEIN: abl interactor 2 [KO:K05751]
100698414  abl interactor 2 isoform X1 [KO:K05751]
100708170  brk1; protein BRICK1 [KO:K05752]
100693709  wasf1; wiskott-Aldrich syndrome protein family member 1 isoform X1 [KO:K05753]
100695482  actin-related protein 2 isoform X1 [KO:K17260]
100710986  actr2; actin-related protein 2 [KO:K17260]
100699229  actin-related protein 3 [KO:K18584]
100709824  actin-related protein 3B isoform X1 [KO:K18584]
100711948  actin-related protein 3 [KO:K18584]
100695429  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
100695691  actin-related protein 2/3 complex subunit 1B [KO:K05757]
100704563  actin-related protein 2/3 complex subunit 1A isoform X1 [KO:K05757]
100699436  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
100709598  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
100702706  actin-related protein 2/3 complex subunit 4 [KO:K05755]
100696600  actin-related protein 2/3 complex subunit 4 [KO:K05755]
100698314  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
100702953  actin-related protein 2/3 complex subunit 5 [KO:K05754]
100694447  actin, cytoplasmic 2-like isoform X1 [KO:K05692]
100534414  actb; actin, cytoplasmic 1 [KO:K05692]
100694183  actin, cytoplasmic 1 [KO:K05692]
100534412  actin, cytoplasmic 2 [KO:K05692]
100700117  profilin-1 [KO:K05759]
100707933  pfn2; profilin-2 isoform X2 [KO:K05759]
100707144  profilin-2 isoform X2 [KO:K05759]
100706266  paxillin isoform X4 [KO:K05760]
100707013  pxn; paxillin isoform X3 [KO:K05760]
100692529  ezr; ezrin [KO:K08007]
100692424  ezrin [KO:K08007]
100697050  radixin isoform X2 [KO:K05762]
100691947  radixin [KO:K05762]
100710883  moesin isoform X1 [KO:K05763]
100702004  moesin isoform X2 [KO:K05763]
100702585  tmsb4x; thymosin beta-4 [KO:K05764]
100699342  cofilin-2 [KO:K05765]
100691336  cofilin-2 [KO:K05765]
100692616  cfl1; cofilin-1 [KO:K05765]
100705960  ssh1; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
100698666  protein phosphatase Slingshot homolog 3 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
100708672  ssh2; LOW QUALITY PROTEIN: protein phosphatase Slingshot homolog 2 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
100702311  protein phosphatase Slingshot homolog 2 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
100694270  protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
100704058  vcl; vinculin [KO:K05700]
100707163  vinculin isoform X7 [KO:K05700]
100707758  iqgap1; ras GTPase-activating-like protein IQGAP1 [KO:K16848]
100712425  iqgap3; ras GTPase-activating-like protein IQGAP3 isoform X1 [KO:K05767]
100705988  iqgap2; ras GTPase-activating-like protein IQGAP2 [KO:K05767]
100699882  gelsolin isoform X1 [KO:K05768]
100712345  gsn; gelsolin isoform X2 [KO:K05768]
100693604  gelsolin [KO:K05768]
102082069  LOW QUALITY PROTEIN: gelsolin [KO:K05768]
100701312  scin; adseverin isoform X1 [KO:K05768]
100696265  alpha-actinin-1 isoform X4 [KO:K05699]
100708272  alpha-actinin-4 isoform X1 [KO:K05699]
100696028  apc2; adenomatous polyposis coli protein 2 [KO:K02085]
100709462  LOW QUALITY PROTEIN: adenomatous polyposis coli protein [KO:K02085]
100693116  arhgef4; rho guanine nucleotide exchange factor 4 isoform X1 [KO:K05769]
100701814  uncharacterized protein LOC100701814 isoform X1 [KO:K05769]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
onl04010  MAPK signaling pathway
onl04510  Focal adhesion
onl04520  Adherens junction
KO pathway
ko04810   
LinkDB

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