Entry |
|
Name |
Acetylcholine chloride (JP18/USP/INN); Miochol (TN) |
Product |
|
Formula |
C7H16NO2. Cl
|
Exact mass |
181.0870
|
Mol weight |
181.66
|
Structure |
|
Simcomp |
|
Class |
Cardiovascular agent
DG01532 Nicotinic cholinergic receptor agonist
Neuropsychiatric agent
DG01490 Muscarinic cholinergic receptor agonist
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
Metabolizing enzyme substrate
DG02974 ACHE substrate
|
Remark |
Product (DG01133): | D00999<JP/US> |
|
Efficacy |
Miotic, Vasodilator (peripheral), Cholinergic receptor agonist |
Comment |
Quaternary ammonium compound
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Metabolism |
|
Interaction |
|
Structure map |
map07220 | Cholinergic and anticholinergic drugs |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB09 Acetylcholine
D00999 Acetylcholine chloride (JP18/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
123 Autonomic nervous system agents
1232 Acetylcholines
D00999 Acetylcholine chloride (JP18/USP/INN)
7 Agents not mainly for therapeutic purpose
72 Intracorporeal diagnostic agents
722 Various function testing reagents
7222 Diagnostic reagents for circulatory function
D00999 Acetylcholine chloride (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01532 Nicotinic cholinergic receptor agonist
DG01133 Acetylcholine
D00999 Acetylcholine chloride
Neuropsychiatric agent
DG01490 Muscarinic cholinergic receptor agonist
DG01133 Acetylcholine
D00999 Acetylcholine chloride
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01133 Acetylcholine
D00999 Acetylcholine chloride
Metabolizing enzyme substrate
DG02974 ACHE substrate
DG01133 Acetylcholine
D00999 Acetylcholine chloride
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00999 Acetylcholine chloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00999 Acetylcholine chloride (JP18/USP/INN) <JP/US>
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN
D00999 Acetylcholine chloride (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00999 Acetylcholine chloride for injection
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00999
Drug groups [BR:br08330]
Cardiovascular agent
DG01532 Nicotinic cholinergic receptor agonist
DG01133 Acetylcholine
Neuropsychiatric agent
DG01490 Muscarinic cholinergic receptor agonist
DG01133 Acetylcholine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01133 Acetylcholine
Metabolizing enzyme substrate
DG02974 ACHE substrate
DG01133 Acetylcholine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 11
1 N1d N 17.4483 -17.4183 #+
2 C1b C 18.5738 -18.0657
3 C1a C 16.6728 -15.9663
4 C1a C 15.9437 -17.4126
5 C1a C 16.6728 -18.8646
6 C1b C 19.7051 -17.4183
7 O7a O 20.8363 -18.0657
8 C7a C 21.9677 -17.4183
9 C1a C 23.0874 -18.0657
10 O6a O 21.9677 -16.1121
11 X Cl 26.5628 -17.6982 #-
BOND 9
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 6 7 1
7 7 8 1
8 8 9 1
9 8 10 2
|