| Entry |
|
|---|
| Name |
Nicotine polacrilex (USP);
Nicorette (TN) |
|---|
| Class |
Metabolizing enzyme substrate
DG01638 CYP2A6 substrate
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
|
|---|
| Remark |
| Product (DG00994): | D03365<JP/US> |
|
|---|
| Efficacy |
Smoking cessation adjunct |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP2A6 [HSA: 1548]
|
|---|
| Interaction |
CYP induction: CYP1A2 [HSA: 1544]
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07B DRUGS USED IN ADDICTIVE DISORDERS
N07BA Drugs used in nicotine dependence
N07BA01 Nicotine
D05157 Nicotine polacrilex (USP)
USP drug classification [BR:br08302]
Anti-Addiction/Substance Abuse Treatment Agents
Smoking Cessation Agents
Nicotine
D05157 Nicotine polacrilex (USP)
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01638 CYP2A6 substrate
DG00994 Nicotine
D05157 Nicotine polacrilex
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00994 Nicotine
D05157 Nicotine polacrilex
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN
D05157 Nicotine polacrilex (USP)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D05157
Rx-to-OTC switch list in the USA [br08315.html]
D05157
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01638 CYP2A6 substrate
DG00994 Nicotine
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00994 Nicotine
|
|---|
| Other DBs |
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|---|
| LinkDB |
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