KEGG   MODULE: M00101
Entry
M00101            Pathway   Module                                 
Name
Cholesterol biosynthesis, FPP => cholesterol
Definition
K00801 K00511 K01852 K05917 (K00222,K19532) K07750 K07748 K13373 K09828 K01824 K00227 K00213
Diagram
M00101

Orthology
K00801  
farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21] [RN:R00702 R02872]
K00511  
squalene monooxygenase [EC:1.14.14.17] [RN:R02874]
K01852  
lanosterol synthase [EC:5.4.99.7] [RN:R03199]
K05917  
sterol 14alpha-demethylase [EC:1.14.14.154] [RN:R05640]
K00222,K19532  
delta14-sterol reductase [EC:1.3.1.70] [RN:R05639]
K07750  
methylsterol monooxygenase [EC:1.14.18.9] [RN:R07509 R12403]
K07748  
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170] [RN:R07494 R12404]
K13373  
3-keto steroid reductase [EC:1.1.1.270] [RN:R07495 R12405]
K09828  
delta24-sterol reductase [EC:1.3.1.72] [RN:R07498]
K01824  
cholestenol delta-isomerase [EC:5.3.3.5] [RN:R03353]
K00227  
delta7-sterol 5-desaturase [EC:1.14.19.20] [RN:R07215]
K00213  
7-dehydrocholesterol reductase [EC:1.3.1.21] [RN:R01451 R01456]
Class
Pathway modules; Lipid metabolism; Sterol biosynthesis
Pathway
map00100  Steroid biosynthesis
map01100  Metabolic pathways
Reaction
R00702  
R02872  
R02874  
R03199  
R05640  
R05639  
R07509  
R07494  
R07495  
R12403  
R12404  
R12405  
R07498  
R03353  
R07215  
R01451,R01456  
Compound
C00448  trans,trans-Farnesyl diphosphate
C03428  Presqualene diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01724  Lanosterol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C05108  14-Demethyllanosterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C05103  4alpha-Methylzymosterol
C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
C22136  Zymosterone
C05437  Zymosterol
C03845  5alpha-Cholest-8-en-3beta-ol
C01189  Lathosterol
C01164  7-Dehydrocholesterol
C00187  Cholesterol
LinkDB

DBGET integrated database retrieval system