| Entry |
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| Symbol |
TUBA8, CDCBM8, MACTHC2, TUBAL2
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| Name |
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| KO |
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| Organism |
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| Pathway |
| hsa05022 | Pathways of neurodegeneration - multiple diseases |
| hsa05130 | Pathogenic Escherichia coli infection |
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| Network |
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| Element |
| N00976 | Retrograde axonal transport |
| N00977 | Mutation-caused aberrant Htt to retrograde axonal transport |
| N00978 | Anterograde axonal transport |
| N00979 | Mutation-caused aberrant Htt to anterograde axonal transport |
| N01018 | Mutation-caused aberrant Abeta to anterograde axonal transport |
| N01055 | Mutation-caused aberrant SNCA to anterograde axonal transport |
| N01158 | Mutation-caused aberrant DCTN1 to retrograde axonal transport |
| N01285 | Microtubule-RHOA signaling pathway |
| N01286 | Escherichia EspG to Microtubule-RHOA signaling pathway |
| N01295 | Rab7-regulated microtubule minus-end directed transport |
| N01297 | Arl8-regulated microtubule plus-end directed transport |
| N01298 | Salmonella SifA to microtubule plus-end directed transport |
| N01299 | Salmonella PipB2 to microtubule plus-end directed transport |
| N01403 | Zn to anterograde axonal transport |
| N01414 | Iron to anterograde axonal transport |
| N01535 | Kinetochore microtubule attachment |
| N01547 | Kinetochore fiber organization |
| N01549 | Branching microtubule nucleation |
| N01553 | Promotion of microtubule growth |
| N01561 | Microtubule depolymerization |
| N01562 | Microtubule depolymerization at the minus ends |
| N01832 | NTN1-MAP1B axon guidance signaling |
| N01833 | DRAXIN-MAP1B axon guidance signaling |
| N01834 | SEMA3A-MAP1B axon guidance signaling |
| N01835 | SEMA3-CRMP2/MAPT axon guidance signaling |
| N01836 | Microtubule plus end regulation network |
| N01837 | Regulation of neurite extension, NAV1-TRIO |
| N01838 | Regulation of synaptic plasticity, p140Cap |
| N01839 | Severing of microtubule, SPAST/KATN |
| N01840 | Severing of microtubule, KIF2A |
| N01841 | Anterograde axonal transport, Kinesin-2 |
| N01842 | Anterograde axonal/dendrite transport, Kinesin-3 |
| N01843 | Anterograde dendrite transport, Kinesin-4 |
| N01844 | Anterograde dendrite transport, Kinesin-6 |
| N01845 | Anterograde axonal/dendrite transport, Kinesin-12 |
| N01846 | Retrograde axonal/dendrite transport, Dynein |
| N01857 | SEMA3A-DCX axon guidance signaling |
| N01858 | EFNB1-MAPT axon guidance signaling |
| N01859 | Anterograde axonal/dendrite transport, Kinesin-1 |
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| Disease |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
51807 (TUBA8)
09143 Cell growth and death
04210 Apoptosis
51807 (TUBA8)
09144 Cellular community - eukaryotes
04530 Tight junction
51807 (TUBA8)
04540 Gap junction
51807 (TUBA8)
09142 Cell motility
04814 Motor proteins
51807 (TUBA8)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
51807 (TUBA8)
05132 Salmonella infection
51807 (TUBA8)
09164 Neurodegenerative disease
05010 Alzheimer disease
51807 (TUBA8)
05012 Parkinson disease
51807 (TUBA8)
05014 Amyotrophic lateral sclerosis
51807 (TUBA8)
05016 Huntington disease
51807 (TUBA8)
05020 Prion disease
51807 (TUBA8)
05022 Pathways of neurodegeneration - multiple diseases
51807 (TUBA8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:hsa03019]
51807 (TUBA8)
03036 Chromosome and associated proteins [BR:hsa03036]
51807 (TUBA8)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
51807 (TUBA8)
04147 Exosome [BR:hsa04147]
51807 (TUBA8)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
P-body specific factors
51807 (TUBA8)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centrosome formation proteins
Microtubules and associated factors
Other tubulins
51807 (TUBA8)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulins
51807 (TUBA8)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
51807 (TUBA8)
Exosomal proteins of other body fluids (saliva and urine)
51807 (TUBA8)
Exosomal proteins of colorectal cancer cells
51807 (TUBA8)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22:18110809..18131732
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| AA seq |
449 aa
MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK
HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD
RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS
QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGTDSFEEENEGEEF |
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| NT seq |
1350 nt +upstreamnt +downstreamnt
atgcgggaatgcatatcagtccacgtgggccaagcgggagttcagattggcaatgcctgc
tgggagctcttctgcctggaacacggcatccaggcagacggcacttttgatgctcaagct
agcaagatcaacgatgatgactccttcaccacctttttcagcgagactggcaatgggaag
catgtgccccgggccgtcatgatagatctggagcctactgtagtggatgaggttcgggca
ggaacctaccgccagctcttccatccagagcagctgatcacaggaaaggaggatgcagcc
aacaactatgcccggggccactacacggtgggcaaggagagcattgacctggtgctggac
cgcatacggaagctgacagatgcttgctctggcctgcagggcttcctgattttccacagt
tttggtgggggcactggctccggcttcacttctctgctgatggaacgcctctccctggat
tatggcaagaaatccaagctggagtttgccatctacccagccccccaggtctctactgca
gtggtggagccctacaactccatcctgaccacccacaccacactggaacattcagattgt
gctttcatggtggacaacgaagccatctatgacatctgccgcaggaaccttgacattgag
cgccctacctataccaacctcaaccgcctcatcagtcagattgtgtcctcaatcactgct
tctctccgctttgacggggccctcaatgtggacctcactgagttccagaccaacctggtg
ccctacccccgcatccacttcccgctggtcacctacgcgcccatcatctctgccgagaaa
gcctatcacgaacagctctctgtggccgagataaccagctcctgctttgagcccaacagc
cagatggtgaagtgcgacccgagacatggcaagtacatggcctgctgcatgctctaccgg
ggcgacgtggtgcccaaggatgtgaatgtcgctattgctgccatcaagaccaagaggacc
atccagtttgtagactggtgtcccacaggcttcaaggtgggcatcaactaccagcccccg
accgtggtccccgggggagacctggccaaggtgcagcgggccgtctgcatgctcagcaac
accacggccattgcggaggcctgggcccgcctcgaccacaagttcgacctcatgtacgcc
aagcgggcctttgtgcattggtatgtgggagaggggatggaagaaggagaattttctgag
gccagggaagacttagctgccctggagaaggattatgaagaagtggggactgattcgttt
gaagaagaaaatgaaggggaggaattttaa |
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