Entry |
|
Symbol |
TUBA3E
|
Name |
(RefSeq) tubulin alpha 3e
|
KO |
|
Organism |
|
Pathway |
hsa05022 | Pathways of neurodegeneration - multiple diseases |
hsa05130 | Pathogenic Escherichia coli infection |
|
Network |
|
Element |
N00976 | Retrograde axonal transport |
N00977 | Mutation-caused aberrant Htt to retrograde axonal transport |
N00978 | Anterograde axonal transport |
N00979 | Mutation-caused aberrant Htt to anterograde axonal transport |
N01018 | Mutation-caused aberrant Abeta to anterograde axonal transport |
N01055 | Mutation-caused aberrant SNCA to anterograde axonal transport |
N01158 | Mutation-caused aberrant DCTN1 to retrograde axonal transport |
N01285 | Microtubule-RHOA signaling pathway |
N01286 | Escherichia EspG to Microtubule-RHOA signaling pathway |
N01295 | Rab7-regulated microtubule minus-end directed transport |
N01297 | Arl8-regulated microtubule plus-end directed transport |
N01298 | Salmonella SifA to microtubule plus-end directed transport |
N01299 | Salmonella PipB2 to microtubule plus-end directed transport |
N01403 | Zn to anterograde axonal transport |
N01414 | Iron to anterograde axonal transport |
N01535 | Kinetochore microtubule attachment |
N01547 | Kinetochore fiber organization |
N01549 | Branching microtubule nucleation |
N01553 | Promotion of microtubule growth |
N01561 | Microtubule depolymerization |
N01562 | Microtubule depolymerization at the minus ends |
N01832 | NTN1-MAP1B axon guidance signaling |
N01833 | DRAXIN-MAP1B axon guidance signaling |
N01834 | SEMA3A-MAP1B axon guidance signaling |
N01835 | SEMA3-CRMP2/MAPT axon guidance signaling |
N01836 | Microtubule plus end regulation network |
N01837 | Regulation of neurite extension, NAV1-TRIO |
N01838 | Regulation of synaptic plasticity, p140Cap |
N01839 | Severing of microtubule, SPAST/KATN |
N01840 | Severing of microtubule, KIF2A |
N01841 | Anterograde axonal transport, Kinesin-2 |
N01842 | Anterograde axonal/dendrite transport, Kinesin-3 |
N01843 | Anterograde dendrite transport, Kinesin-4 |
N01844 | Anterograde dendrite transport, Kinesin-6 |
N01845 | Anterograde axonal/dendrite transport, Kinesin-12 |
N01846 | Retrograde axonal/dendrite transport, Dynein |
N01857 | SEMA3A-DCX axon guidance signaling |
N01858 | EFNB1-MAPT axon guidance signaling |
N01859 | Anterograde axonal/dendrite transport, Kinesin-1 |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
112714 (TUBA3E)
09142 Cell motility
04814 Motor proteins
112714 (TUBA3E)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
112714 (TUBA3E)
09164 Neurodegenerative disease
05010 Alzheimer disease
112714 (TUBA3E)
05012 Parkinson disease
112714 (TUBA3E)
05014 Amyotrophic lateral sclerosis
112714 (TUBA3E)
05016 Huntington disease
112714 (TUBA3E)
05020 Prion disease
112714 (TUBA3E)
05022 Pathways of neurodegeneration - multiple diseases
112714 (TUBA3E)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:hsa03019]
112714 (TUBA3E)
03036 Chromosome and associated proteins [BR:hsa03036]
112714 (TUBA3E)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
112714 (TUBA3E)
04147 Exosome [BR:hsa04147]
112714 (TUBA3E)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
P-body specific factors
112714 (TUBA3E)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centrosome formation proteins
Microtubules and associated factors
Other tubulins
112714 (TUBA3E)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulins
112714 (TUBA3E)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
112714 (TUBA3E)
Exosomal proteins of other body fluids (saliva and urine)
112714 (TUBA3E)
Exosomal proteins of colorectal cancer cells
112714 (TUBA3E)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
2:complement(130191745..130198439)
|
AA seq |
450 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLD
RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSE
AREDLAALEKDCEEVGVDSVEAEAEEGEAY |
NT seq |
1353 nt +upstreamnt +downstreamnt
atgcgcgagtgtatctctatccacgtggggcaggcgggtgtccagatcggcaatgcctgc
tgggaactgtactgccttgaacatggaattcagcccgatggtcaaatgccaagtgataaa
accattggtggcggggacgactccttcaacacgttcttcagtgagactggagctggcaag
cacgtgcccagagcagtgtttgtggacctggagcccactgtggtcgatgaagtgcgcaca
gggacctacaggcagctcttccacccagagcagctgatcaccgggaaggaagatgcagcc
agtaattacgccaggggccattacaccatcggcaaggagattgttgacctagtcctggac
cggatccgcaaactggcggatctgtgcacaggactgcagggcttcctcatcttccacagc
tttgggggcggcactggctctgggttcgcatctctgctcatggagcggctctcagtggat
tacagcaagaagtccaagctagagtttgccatttacccagccccccaggtctccacagcc
gtggtggagccctacaactccatcctaaccacccacacgaccctggaacattctgactgt
gccttcatggtcgacaatgaagccatctatgacatatgtcggcgcaacctggacattgaa
cgtcccacgtacaccaacctcaatcgcctgattgggcagatcgtgtcctccatcacggcc
tccctgcgatttgatggggccctgaatgtggacttgacggaattccagaccaacctcgtg
ccgtacccccgcatccacttccccctggccacctacgccccagtcatctcagctgagaag
gcctaccacgagcagctgtctgtggccgagatcaccaatgcctgcttcgagccagccaat
cagatggtcaagtgtgaccctcgccatggcaagtacatggcctgctgcatgttgtacagg
ggggacgtggtccccaaagacgtcaatgcggccatcgccaccatcaagaccaagcgcact
atccagtttgtggattggtgcccgactggatttaaggtgggcattaactaccagcccccc
acagtggtccccgggggagacctggccaaggtgcagcgggccgtgtgcatgctgagcaac
accacggccattgcggaggcctgggcccgcctggtccataagttcgatctcatgtatgcc
aagtgggcctttgtgcactggtacgtgggcgaaggcatggaagagggagagttctctgag
gcccgcgaggacctggcagctctagagaaggattgtgaagaggtgggcgtggattccgtg
gaagctgaggctgaagaaggcgaagcatactga |