| Entry |
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| Name |
Microtubule depolymerization at the minus ends
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| Definition |
PLK1 -> KIF2A == DDA3 == microtubule |
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| Expanded |
5347 -> 3796 == 84722 == (7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688) |
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| Class |
nt06515 Regulation of kinetochore-microtubule interactions
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| Type |
Reference
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| Gene |
| 5347 | PLK1; polo like kinase 1 |
| 3796 | KIF2A; kinesin family member 2A |
| 84722 | PSRC1; proline and serine rich coiled-coil 1 |
| 7846 | TUBA1A; tubulin alpha 1a |
| 10376 | TUBA1B; tubulin alpha 1b |
| 84790 | TUBA1C; tubulin alpha 1c |
| 7278 | TUBA3C; tubulin alpha 3c |
| 113457 | TUBA3D; tubulin alpha 3d |
| 112714 | TUBA3E; tubulin alpha 3e |
| 7277 | TUBA4A; tubulin alpha 4a |
| 51807 | TUBA8; tubulin alpha 8 |
| 203068 | TUBB; tubulin beta class I |
| 81027 | TUBB1; tubulin beta 1 class VI |
| 7280 | TUBB2A; tubulin beta 2A class IIa |
| 347733 | TUBB2B; tubulin beta 2B class IIb |
| 10381 | TUBB3; tubulin beta 3 class III |
| 10382 | TUBB4A; tubulin beta 4A class IVa |
| 10383 | TUBB4B; tubulin beta 4B class IVb |
| 84617 | TUBB6; tubulin beta 6 class V |
| 347688 | TUBB8; tubulin beta 8 class VIII |
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| Reference |
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| Authors |
Kwon HJ, Park JE, Song H, Jang CY |
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| Title |
DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics. |
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| Journal |
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| Reference |
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| Authors |
Jang CY, Wong J, Coppinger JA, Seki A, Yates JR 3rd, Fang G |
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| Title |
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement. |
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| Journal |
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| Reference |
|
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| Authors |
Jang CY, Coppinger JA, Seki A, Yates JR 3rd, Fang G |
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| Title |
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a. |
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| Journal |
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| LinkDB |
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