KEGG   NETWORK: N01839
Entry
N01839                      Network                                
Name
Severing of microtubule, SPAST/KATN
Definition
SPAST,(KATNA1+KATNB1) -| (TUBA+TUBB)
  Expanded
6683,(11104+10300) -| ((7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688))
Class
nt06541 Cytoskeleton in neurons
Type
Reference
Gene
6683  SPAST; spastin
11104  KATNA1; katanin catalytic subunit A1
10300  KATNB1; katanin regulatory subunit B1
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
Reference
PMID:22595526
  Authors
Sharp DJ, Ross JL
  Title
Microtubule-severing enzymes at the cutting edge.
  Journal
J Cell Sci 125:2561-9 (2012)
DOI:10.1242/jcs.101139
Reference
PMID:33183955
  Authors
Kuo YW, Howard J
  Title
Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes.
  Journal
Trends Cell Biol 31:50-61 (2021)
DOI:10.1016/j.tcb.2020.10.004
Reference
PMID:35865632
  Authors
Costa AC, Sousa MM
  Title
The Role of Spastin in Axon Biology.
  Journal
Front Cell Dev Biol 10:934522 (2022)
DOI:10.3389/fcell.2022.934522
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