KEGG   REACTION: R00946
Entry
R00946                      Reaction                               
Name
5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
Definition
5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine
Equation
C00440 + C00155 <=> C00101 + C00073
Reaction class
RC00035  C00073_C00155
RC00113  C00101_C00440
Enzyme
2.1.1.13
Pathway
rn00270  Cysteine and methionine metabolism
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13
     R00946  5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine
Orthology
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Other DBs
RHEA: 11175
LinkDB

KEGG   RCLASS: RC00113
Entry
RC00113                     RClass                                 
Definition
N1x-N1y:*-C1a:C1y+C8y-C1y+C8y
Reactant pair
C00101_C00440    C01217_C04488    C02673_C04578
C04144_C04489    C06542_C11810    C11809_C15985
C18799_C18802
Related class
Reaction
R00946 R02289 R02573 R02912 R04013 R04347 R04405 R05881
R09096 R09270 R09271 R09365 R10136 R10219 R10243 R10333
R10385 R12138 R12291 R12999
Enzyme
2.1.1.13        2.1.1.14        2.1.1.19        2.1.1.99        
2.1.1.245       2.1.1.258       2.1.1.269       2.1.1.341       
2.1.1.378       2.1.1.384       2.1.1.385       2.1.1.389       
2.1.1.-         2.3.1.169       7.2.1.4
Pathway
rn00670  One carbon pool by folate
rn00720  Other carbon fixation pathways
rn00901  Indole alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K00193  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00549  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
K00577  tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
K00578  tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
K00579  tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
K00580  tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
K00581  tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
K00582  tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
K00583  tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
K00584  tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
K00599  tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
K14138  acetyl-CoA synthase [EC:2.3.1.169]
K15023  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
K15064  syringate O-demethylase [EC:2.1.1.-]
K15066  vanillate/3-O-methylgallate O-demethylase [EC:2.1.1.341]
K17486  dimethylsulfoniopropionate demethylase [EC:2.1.1.269]
K21896  3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase [EC:2.1.1.99]
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
K25221  [methyl-Co(III) glycine betaine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.378]
K25915  [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.385]
K26930  [methyl-Co(III) quaternary-amine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.389]
K27779  norajmaline N-methyltransferase [EC:2.1.1.-]

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