KEGG   REACTION: R08231
Entry
R08231                      Reaction                               
Name
5-fluorouridine monophosphate:diphosphate phospho-alpha-D-ribosyl-transferase
Definition
5-FU + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 5-Fluorouridine monophosphate + Diphosphate
Equation
C07649 + C00119 <=> C16634 + C00013
Reaction class
RC00063  C07649_C16634
Enzyme
2.4.2.10
Pathway
rn00983  Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.10
     R08231  5-FU + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 5-Fluorouridine monophosphate + Diphosphate
Orthology
K13421  uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
LinkDB

KEGG   RCLASS: RC00063
Entry
RC00063                     RClass                                 
Definition
N4x-N4y:*-C1y:C8x+C8y-C8x+C8y
Reactant pair
C00002_C00147    C00020_C00147    C00021_C00147
C00055_C00380    C00105_C00106    C00106_C00299
C00106_C00526    C00130_C00262    C00144_C00242
C00147_C00170    C00147_C00212    C00147_C00559
C00147_C20773    C00178_C00214    C00178_C00364
C00242_C00330    C00242_C00387    C00242_C01977
C00262_C00294    C00262_C05512    C00262_C16999
C00262_C19787    C00371_C16431    C00380_C00475
C01449_C01978    C02029_C16447    C02216_C02494
C02860_C16676    C02872_C04339    C03114_C04778
C04051_C04677    C04083_C16427    C07648_C16619
C07649_C11736    C07649_C12673    C07649_C12739
C07649_C16633    C07649_C16634    C15545_C16449
C16675_C20446
 » show all
Related class
Reaction
R00182 R00190 R00194 R00510 R00966 R01080 R01128 R01132
R01229 R01245 R01401 R01402 R01561 R01570 R01677 R01770
R01863 R01876 R01969 R02137 R02147 R02296 R02484 R02486
R02557 R02748 R02806 R03789 R03885 R04074 R04148 R04378
R08072 R08073 R08074 R08080 R08222 R08225 R08229 R08230
R08231 R08245 R08369 R08587 R09668 R09675 R10185 R10209
R10668 R10836 R10837 R10838 R12955 R12956
Enzyme
1.14.11.10      1.14.14.-       2.4.1.118       2.4.2.1         
2.4.2.2         2.4.2.3         2.4.2.4         2.4.2.6         
2.4.2.7         2.4.2.8         2.4.2.9         2.4.2.10        
2.4.2.15        2.4.2.21        2.4.2.22        2.4.2.28        
2.4.2.29        2.4.2.36        2.4.2.44        2.4.2.52        
2.4.2.57        2.4.2.64        2.7.8.37        3.2.2.1         
3.2.2.2         3.2.2.3         3.2.2.4         3.2.2.7         
3.2.2.8         3.2.2.9         3.2.2.10        3.2.2.12        
3.2.2.13        3.2.2.16        3.2.2.26        3.2.2.30
Pathway
rn00230  Purine metabolism
rn00240  Pyrimidine metabolism
rn00860  Porphyrin metabolism
rn00908  Zeatin biosynthesis
rn00983  Drug metabolism - other enzymes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01232  Nucleotide metabolism
rn01240  Biosynthesis of cofactors
RModule
RM045  Conversion of base / nucleoside / nucleotide
Orthology
K00756  pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]
K00757  uridine phosphorylase [EC:2.4.2.3]
K00758  thymidine phosphorylase [EC:2.4.2.4]
K00759  adenine phosphoribosyltransferase [EC:2.4.2.7]
K00760  hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00761  uracil phosphoribosyltransferase [EC:2.4.2.9]
K00768  nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21]
K00769  xanthine phosphoribosyltransferase [EC:2.4.2.22]
K00772  5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
K00773  queuine tRNA-ribosyltransferase [EC:2.4.2.29]
K00777  queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
K01239  purine nucleosidase [EC:3.2.2.1]
K01240  uridine nucleosidase [EC:3.2.2.3]
K01241  AMP nucleosidase [EC:3.2.2.4]
K01243  adenosylhomocysteine nucleosidase [EC:3.2.2.9]
K01244  5'-methylthioadenosine nucleosidase [EC:3.2.2.16]
K01250  pyrimidine-specific ribonucleoside hydrolase [EC:3.2.2.-]
K02825  pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
K03783  purine-nucleoside phosphorylase [EC:2.4.2.1]
K03784  purine-nucleoside phosphorylase [EC:2.4.2.1]
K03816  xanthine phosphoribosyltransferase [EC:2.4.2.22]
K05780  alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [EC:2.7.8.37]
K05810  purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K05966  triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
K06164  alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI [EC:2.7.8.37]
K06165  alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH [EC:2.7.8.37]
K06166  alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [EC:2.7.8.37]
K06966  pyrimidine/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-]
K09913  purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]
K10213  ribosylpyrimidine nucleosidase [EC:3.2.2.8]
K11783  futalosine hydrolase [EC:3.2.2.26]
K12700  non-specific riboncleoside hydrolase [EC:3.2.2.-]
K13421  uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
K13927  holo-ACP synthase / triphosphoribosyl-dephospho-CoA synthase [EC:2.7.7.61 2.4.2.52]
K13930  triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
K15780  bifunctional protein TilS/HprT [EC:6.3.4.19 2.4.2.8]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K18284  adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30]
K18931  AMP phosphorylase [EC:2.4.2.57]
K19696  5'-methylthioinosine phosphorylase [EC:2.4.2.44]
K19836  hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K25589  inosine/uridine nucleosidase [EC:3.2.2.2 3.2.2.3]
K26211  guanosine phosphorylase [EC:2.4.2.15]
K26212  guanosine phosphorylase [EC:2.4.2.15]

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