KEGG   REACTION: R12556
Entry
R12556                      Reaction                               
Name
UDP-N-acetyl-alpha-D-quinovosamine:NADP+ 4-dehydrogenase
Definition
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+
Equation
C04613 + C00005 + C00080 <=> C22262 + C00006
Comment
NADH (see R12760)
Reaction class
RC00182  C04613_C22262
Enzyme
1.1.1.426       1.1.1.-
Pathway
rn00541  Biosynthesis of various nucleotide sugars
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Module
M01009  UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.426
     R12556  UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+
    1.1.1.-
     R12556  UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+
Orthology
K24310  UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase [EC:1.1.1.426]
K24311  UDP-4-keto-6-deoxy-GlcNAc-4-reductase [EC:1.1.1.-]
Other DBs
RHEA: 68555
LinkDB

KEGG   RCLASS: RC00182
Entry
RC00182                     RClass                                 
Definition
C1y-C5x:*-*:C1y+C1y+O1a-C1y+C1y+O5x
Reactant pair
C00002_C07024    C00029_C12210    C00031_C02779
C00043_C20849    C00089_C05731    C00092_C20668
C00137_C00691    C00243_C05403    C00325_C14830
C00688_C03187    C00688_C03319    C00691_C06153
C00691_C21643    C01222_C02977    C01222_C03117
C01295_C03365    C01295_C03844    C01759_C21176
C01822_C20509    C02199_C17328    C04280_C04673
C04573_C20395    C04613_C22261    C04613_C22262
C07277_C11907    C11912_C11926    C11919_C21074
C11920_C11927    C11921_C21071    C11922_C11923
C17584_C21176    C17701_C21265    C18092_C21137
C19823_C20768    C19891_C20251    C20368_C20369
C20369_C20370    C20768_C20769    C20769_C22259
C21317_C21318
 » show all
Related class
Reaction
R00302 R00807 R00808 R01183 R01680 R02776 R02777 R03396
R03397 R03398 R03399 R03497 R03498 R05668 R05687 R06434
R06438 R06446 R06594 R07060 R08705 R08843 R09951 R09953
R09954 R10112 R10113 R10140 R10190 R10417 R10519 R10573
R10665 R10785 R11042 R11047 R11139 R11265 R11266 R11290
R11433 R11770 R12552 R12555 R12556 R12604 R12760
Enzyme
1.1.1.18        1.1.1.133       1.1.1.134       1.1.1.135       
1.1.1.142       1.1.1.143       1.1.1.187       1.1.1.266       
1.1.1.271       1.1.1.281       1.1.1.333       1.1.1.335       
1.1.1.339       1.1.1.344       1.1.1.355       1.1.1.361       
1.1.1.364       1.1.1.367       1.1.1.369       1.1.1.370       
1.1.1.371       1.1.1.374       1.1.1.426       1.1.1.-         
1.1.3.10        1.1.98.3        1.1.99.13       1.-.-.-
Pathway
rn00051  Fructose and mannose metabolism
rn00404  Staurosporine biosynthesis
rn00500  Starch and sucrose metabolism
rn00521  Streptomycin biosynthesis
rn00523  Polyketide sugar unit biosynthesis
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00541  Biosynthesis of various nucleotide sugars
rn00562  Inositol phosphate metabolism
rn00998  Biosynthesis of various antibiotics
rn01051  Biosynthesis of ansamycins
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01250  Biosynthesis of nucleotide sugars
RModule
RM036  Epimerization and reduction in deoxysugar biosynthesis
Orthology
K00010  myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
K00067  dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
K12451  3,5-epimerase/4-reductase [EC:5.1.3.- 1.1.1.-]
K12628  puromycin biosynthesis protein Pur10 [EC:1.-.-.-]
K13016  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]
K13020  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]
K13306  dTDP-4-dehydro-6-deoxyglucose reductase [EC:1.1.1.266]
K13313  dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase [EC:1.1.1.364]
K13319  4-ketoreductase
K13322  dTDP-4-keto-6-deoxyhexose 4-ketoreductase
K15856  GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
K16015  oxidoreductase [EC:1.1.1.-]
K16043  scyllo-inositol 2-dehydrogenase (NAD+) [EC:1.1.1.370]
K16044  scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.371]
K18652  glucose-6-phosphate 3-dehydrogenase [EC:1.1.1.361]
K19068  UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase [EC:1.1.1.367]
K19180  dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) [EC:1.1.1.339]
K19652  dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+] [EC:1.1.1.344]
K19857  dTDP-4-keto-6-deoxy-L-hexose 4-reductase
K20085  dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose reductase [EC:1.1.1.-]
K20152  2'-dehydrokanamycin reductase [EC:1.1.1.355]
K20569  NAD+-dependent dehydrogenase [EC:1.1.1.-]
K20570  NADPH-dependent reductase [EC:1.1.1.-]
K20571  dehydrogenase [EC:1.1.1.-]
K20590  gentamicin A2 dehydrogenase [EC:1.1.1.-]
K21214  NDP-hexose 4-ketoreductase
K22230  scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-]
K22231  scyllo-inosose 3-dehydrogenase [EC:1.1.1.-]
K22252  GDP-6-deoxy-D-talose 4-dehydrogenase [EC:1.1.1.135]
K23987  dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
K24310  UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase [EC:1.1.1.426]
K24311  UDP-4-keto-6-deoxy-GlcNAc-4-reductase [EC:1.1.1.-]
K24312  UDP-4-keto-D-FucNAc 4-reductase

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