KEGG   PATHWAY: afor00330
Entry
afor00330                   Pathway                                
Name
Arginine and proline metabolism - Aptenodytes forsteri (emperor penguin)
Class
Metabolism; Amino acid metabolism
Pathway map
afor00330  Arginine and proline metabolism
afor00330

Module
afor_M00015  Proline biosynthesis, glutamate => proline [PATH:afor00330]
afor_M00047  Creatine pathway [PATH:afor00330]
afor_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:afor00330]
afor_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:afor00330]
afor_M00970  Proline degradation, proline => glutamate [PATH:afor00330]
afor_M00972  Proline metabolism [PATH:afor00330]
Other DBs
GO: 0006525 0006560
Organism
Aptenodytes forsteri (emperor penguin) [GN:afor]
Gene
103893982  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103894609  NOS1; nitric oxide synthase, brain isoform X2 [KO:K13240] [EC:1.14.13.39]
103895493  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
103895858  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
103896035  [KO:K11182] [EC:1.4.3.22]
103896712  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
103896768  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
103896769  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
103896965  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
103896971  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
103897686  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
103897783  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
103897800  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
103897858  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103898009  [KO:K00128] [EC:1.2.1.3]
103898011  [KO:K00128] [EC:1.2.1.3]
103898064  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
103898780  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
103899063  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
103899405  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
103899883  [KO:K00933] [EC:2.7.3.2]
103900226  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
103900350  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103901252  [KO:K00318] [EC:1.5.5.2]
103901304  PYCRL; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
103902031  [KO:K00274] [EC:1.4.3.4]
103902105  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
103902490  ARG2; LOW QUALITY PROTEIN: arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
103902759  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
103902772  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
103903064  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103903299  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
103903564  AZIN2; antizyme inhibitor 2 isoform X2 [KO:K01583] [EC:4.1.1.19]
103904447  P4HA2; prolyl 4-hydroxylase subunit alpha-2 [KO:K00472] [EC:1.14.11.2]
103904644  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
103907059  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
103907410  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
103907426  AGMAT; agmatinase, mitochondrial [KO:K27001]
103907566  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
103908336  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103908408  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
afor00020  Citrate cycle (TCA cycle)
afor00220  Arginine biosynthesis
afor00250  Alanine, aspartate and glutamate metabolism
afor00260  Glycine, serine and threonine metabolism
afor00270  Cysteine and methionine metabolism
afor00310  Lysine degradation
afor00410  beta-Alanine metabolism
afor00470  D-Amino acid metabolism
afor00480  Glutathione metabolism
afor00630  Glyoxylate and dicarboxylate metabolism
afor00650  Butanoate metabolism
afor00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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