KEGG   PATHWAY: aou00230
Entry
aou00230                    Pathway                                
Name
Purine metabolism - Actinoplanes oblitus
Class
Metabolism; Nucleotide metabolism
Pathway map
aou00230  Purine metabolism
aou00230

Module
aou_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aou00230]
aou_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aou00230]
aou_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aou00230]
aou_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aou00230]
aou_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aou00230]
aou_M00546  Purine degradation, xanthine => urea [PATH:aou00230]
aou_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:aou00230]
Other DBs
GO: 0006163 0042278
Organism
Actinoplanes oblitus [GN:aou]
Gene
ACTOB_000068  [KO:K00759] [EC:2.4.2.7]
ACTOB_000113  [KO:K01939] [EC:6.3.4.4]
ACTOB_000114  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ACTOB_000116  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ACTOB_000117  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
ACTOB_000118  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
ACTOB_000119  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
ACTOB_000122  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ACTOB_000123  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ACTOB_000462  [KO:K00525] [EC:1.17.4.1]
ACTOB_000463  [KO:K00526] [EC:1.17.4.1]
ACTOB_000640  [KO:K00939] [EC:2.7.4.3]
ACTOB_000705  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
ACTOB_000706  [KO:K00088] [EC:1.1.1.205]
ACTOB_000710  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
ACTOB_000725  [KO:K01081] [EC:3.1.3.5]
ACTOB_000735  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ACTOB_000736  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ACTOB_000753  cysC; adenylyl-sulfate kinase [KO:K00958] [EC:2.7.7.4]
ACTOB_000772  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ACTOB_000814  [KO:K01589] [EC:6.3.4.18]
ACTOB_000815  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ACTOB_000981  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
ACTOB_001202  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ACTOB_001340  [KO:K01129] [EC:3.1.5.1]
ACTOB_001463  [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ACTOB_001471  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ACTOB_001609  [KO:K00856] [EC:2.7.1.20]
ACTOB_001626  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ACTOB_001876  [KO:K02566] [EC:3.1.3.5]
ACTOB_002848  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
ACTOB_002959  [KO:K11177] [EC:1.17.1.4]
ACTOB_002960  [KO:K11178] [EC:1.17.1.4]
ACTOB_002961  [KO:K13483]
ACTOB_003751  [KO:K05873] [EC:4.6.1.1]
ACTOB_004334  [KO:K03651] [EC:3.1.4.53]
ACTOB_005089  [KO:K07816] [EC:2.7.6.5]
ACTOB_005098  [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ACTOB_005314  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ACTOB_006451  [KO:K07127] [EC:3.5.2.17]
ACTOB_006646  [KO:K00939] [EC:2.7.4.3]
ACTOB_006735  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ACTOB_006778  [KO:K01430] [EC:3.5.1.5]
ACTOB_006779  [KO:K01429] [EC:3.5.1.5]
ACTOB_006780  [KO:K01428] [EC:3.5.1.5]
ACTOB_006797  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ACTOB_006798  [KO:K00759] [EC:2.4.2.7]
ACTOB_006815  [KO:K19710] [EC:2.7.7.53]
ACTOB_006882  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
ACTOB_006883  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
ACTOB_006889  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
ACTOB_006890  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ACTOB_006891  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
ACTOB_007003  [KO:K01939] [EC:6.3.4.4]
ACTOB_007025  [KO:K00948] [EC:2.7.6.1]
ACTOB_007348  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ACTOB_007435  [KO:K00525] [EC:1.17.4.1]
ACTOB_007864  [KO:K05873] [EC:4.6.1.1]
ACTOB_008100  [KO:K01488] [EC:3.5.4.4]
ACTOB_008119  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
ACTOB_008120  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
ACTOB_008125  [KO:K00948] [EC:2.7.6.1]
ACTOB_008428  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ACTOB_008482  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ACTOB_008518  [KO:K01923] [EC:6.3.2.6]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aou00030  Pentose phosphate pathway
aou00220  Arginine biosynthesis
aou00250  Alanine, aspartate and glutamate metabolism
aou00260  Glycine, serine and threonine metabolism
aou00340  Histidine metabolism
aou00630  Glyoxylate and dicarboxylate metabolism
aou00730  Thiamine metabolism
aou00740  Riboflavin metabolism
aou00790  Folate biosynthesis
KO pathway
ko00230   

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