KEGG   PATHWAY: aqs00230
Entry
aqs00230                    Pathway                                
Name
Purine metabolism - Aquitalea sp. USM4
Class
Metabolism; Nucleotide metabolism
Pathway map
aqs00230  Purine metabolism
aqs00230

Module
aqs_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aqs00230]
aqs_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aqs00230]
aqs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aqs00230]
aqs_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aqs00230]
aqs_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aqs00230]
Other DBs
GO: 0006163 0042278
Organism
Aquitalea sp. USM4 [GN:aqs]
Gene
DKK66_01640  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
DKK66_10415  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
DKK66_17010  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
DKK66_10040  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
DKK66_00120  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DKK66_08620  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DKK66_11580  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DKK66_10460  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
DKK66_16950  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
DKK66_11585  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DKK66_06070  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
DKK66_06075  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DKK66_06065  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DKK66_04415  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DKK66_08610  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DKK66_04170  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DKK66_10520  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
DKK66_10420  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
DKK66_15255  DUF1255 domain-containing protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
DKK66_16930  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DKK66_08580  rihB; ribonucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
DKK66_04830  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DKK66_02660  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
DKK66_02360  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DKK66_04610  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
DKK66_05770  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
DKK66_12490  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
DKK66_14990  GMP reductase [KO:K00364] [EC:1.7.1.7]
DKK66_04160  guanylate kinase [KO:K00942] [EC:2.7.4.8]
DKK66_16925  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
DKK66_13085  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
DKK66_16910  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
DKK66_17940  ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
DKK66_15175  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
DKK66_16905  dGTPase [KO:K01129] [EC:3.1.5.1]
DKK66_04150  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DKK66_02780  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DKK66_10395  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
DKK66_02290  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
DKK66_06035  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
DKK66_12345  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
DKK66_03590  adenylate kinase [KO:K00939] [EC:2.7.4.3]
DKK66_10005  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
DKK66_15960  sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
DKK66_15955  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
DKK66_11815  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
DKK66_11825  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
DKK66_11820  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
DKK66_19045  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
DKK66_11835  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
DKK66_19050  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
DKK66_11840  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
DKK66_00360  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
DKK66_00365  urease subunit beta [KO:K01429] [EC:3.5.1.5]
DKK66_00370  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
DKK66_04190  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
DKK66_12675  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aqs00030  Pentose phosphate pathway
aqs00220  Arginine biosynthesis
aqs00250  Alanine, aspartate and glutamate metabolism
aqs00260  Glycine, serine and threonine metabolism
aqs00340  Histidine metabolism
aqs00630  Glyoxylate and dicarboxylate metabolism
aqs00730  Thiamine metabolism
aqs00740  Riboflavin metabolism
aqs00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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