KEGG   PATHWAY: ath00100
Entry
ath00100                    Pathway                                
Name
Steroid biosynthesis - Arabidopsis thaliana (thale cress)
Class
Metabolism; Lipid metabolism
Pathway map
ath00100  Steroid biosynthesis
ath00100

Module
ath_M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol [PATH:ath00100]
Other DBs
GO: 0016126
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT4G34650  SQS2; squalene synthase 2 [KO:K00801] [EC:2.5.1.21]
AT4G34640  SQS1; squalene synthase 1 [KO:K00801] [EC:2.5.1.21]
AT1G58440  XF1; FAD/NAD(P)-binding oxidoreductase family protein [KO:K00511] [EC:1.14.14.17]
AT4G37760  SQE3; squalene epoxidase 3 [KO:K00511] [EC:1.14.14.17]
AT5G24140  SQP2; squalene monooxygenase 2 [KO:K00511] [EC:1.14.14.17]
AT5G24160  SQE6; squalene monooxygenase 6 [KO:K00511] [EC:1.14.14.17]
AT2G22830  SQE2; squalene epoxidase 2 [KO:K00511] [EC:1.14.14.17]
AT5G24150  SQP1; FAD/NAD(P)-binding oxidoreductase family protein [KO:K00511] [EC:1.14.14.17]
AT3G45130  LAS1; lanosterol synthase 1 [KO:K01852] [EC:5.4.99.7]
AT1G11680  CYP51G1; CYTOCHROME P450 51G1 [KO:K05917] [EC:1.14.14.154 1.14.15.36]
AT3G52940  FK; Ergosterol biosynthesis ERG4/ERG24 family [KO:K00222] [EC:1.3.1.70]
AT1G20050  HYD1; C-8,7 sterol isomerase [KO:K01824] [EC:5.3.3.5]
AT3G19820  DWF1; cell elongation protein / DWARF1 / DIMINUTO (DIM) [KO:K09828] [EC:1.3.1.72 1.3.1.-]
AT3G02580  STE1; sterol 1 [KO:K00227] [EC:1.14.19.20]
AT3G02590  Fatty acid hydroxylase superfamily protein [KO:K00227] [EC:1.14.19.20]
AT1G50430  DWF5; Ergosterol biosynthesis ERG4/ERG24 family [KO:K00213] [EC:1.3.1.21]
AT2G15230  LIP1; lipase 1 [KO:K01052] [EC:3.1.1.13]
AT3G57140  SDP1-LIKE; sugar-dependent 1-like protein [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
AT5G04040  SDP1; Patatin-like phospholipase family protein [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
AT5G13710  SMT1; sterol methyltransferase 1 [KO:K00559] [EC:2.1.1.41]
AT2G07050  CAS1; cycloartenol synthase 1 [KO:K01853] [EC:5.4.99.8]
AT4G12110  SMO1-1; sterol-4alpha-methyl oxidase 1-1 [KO:K14423] [EC:1.14.18.10]
AT4G22756  SMO1-2; sterol C4-methyl oxidase 1-2 [KO:K14423] [EC:1.14.18.10]
AT4G22755  methylsterol monooxygenase 1-3 [KO:K14423] [EC:1.14.18.10]
AT2G26260  3BETAHSD/D2; 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 [KO:K23558] [EC:1.1.1.418]
AT2G43420  3-beta hydroxysteroid dehydrogenase/isomerase family protein [KO:K23558] [EC:1.1.1.418]
AT1G47290  3BETAHSD/D1; 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 [KO:K23558] [EC:1.1.1.418]
AT5G50375  CPI1; cyclopropyl isomerase [KO:K08246] [EC:5.5.1.9]
AT1G20330  SMT2; sterol methyltransferase 2 [KO:K08242] [EC:2.1.1.143]
AT1G76090  SMT3; sterol methyltransferase 3 [KO:K08242] [EC:2.1.1.143]
AT1G07420  SMO2-1; sterol 4-alpha-methyl-oxidase 2-1 [KO:K14424] [EC:1.14.18.11]
AT2G29390  SMO2-2; sterol 4-alpha-methyl-oxidase 2-2 [KO:K14424] [EC:1.14.18.11]
AT2G28850  CYP710A3; cytochrome P450, family 710, subfamily A, polypeptide 3 [KO:K09832] [EC:1.14.19.41]
AT2G28860  CYP710A4; cytochrome P450, family 710, subfamily A, polypeptide 4 [KO:K09832] [EC:1.14.19.41]
AT2G34490  CYP710A2; cytochrome P450, family 710, subfamily A, polypeptide 2 [KO:K09832] [EC:1.14.19.41]
AT2G34500  CYP710A1; cytochrome P450, family 710, subfamily A, polypeptide 1 [KO:K09832] [EC:1.14.19.41]
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01164  7-Dehydrocholesterol
C01189  Lathosterol
C01561  Calcidiol
C01673  Calcitriol
C01694  Ergosterol
C01724  Lanosterol
C01753  beta-Sitosterol
C01789  Campesterol
C01802  Desmosterol
C01902  Cycloartenol
C01943  Obtusifoliol
C02141  Cycloeucalenol
C02530  Cholesterol ester
C03428  Presqualene diphosphate
C03845  5alpha-Cholest-8-en-3beta-ol
C04525  Fecosterol
C05103  4alpha-Methylzymosterol
C05107  7-Dehydrodesmosterol
C05108  14-Demethyllanosterol
C05109  24,25-Dihydrolanosterol
C05437  Zymosterol
C05439  5alpha-Cholesta-7,24-dien-3beta-ol
C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  Vitamin D2
C05442  Stigmasterol
C05443  Vitamin D3
C07712  Secalciferol
C08813  Brassicasterol
C08821  Isofucosterol
C08830  24-Methylidenecycloartanol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  24-Methylenelophenol
C11523  24-Ethylidenelophenol
C15776  4alpha-Methylfecosterol
C15777  Episterol
C15780  5-Dehydroepisterol
C15781  24-Methylenecholesterol
C15782  Delta7-Avenasterol
C15783  5-Dehydroavenasterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  Calcitetrol
C21106  24-epi-Campesterol
C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
C22116  3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate
C22119  3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate
C22120  4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
C22121  Cycloeucalenone
C22122  Episterone
C22123  Avenastenone
C22136  Zymosterone
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
DOI:10.1105/tpc.105.036012
Reference
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)
DOI:10.1023/A:1023005504702
Related
pathway
ath00900  Terpenoid backbone biosynthesis
ath00905  Brassinosteroid biosynthesis
KO pathway
ko00100   
LinkDB

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