KEGG   PATHWAY: avn00230
Entry
avn00230                    Pathway                                
Name
Purine metabolism - Azotobacter vinelandii DJ
Class
Metabolism; Nucleotide metabolism
Pathway map
avn00230  Purine metabolism
avn00230

Module
avn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:avn00230]
avn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:avn00230]
avn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:avn00230]
avn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:avn00230]
avn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:avn00230]
avn_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:avn00230]
avn_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:avn00230]
Other DBs
GO: 0006163 0042278
Organism
Azotobacter vinelandii DJ [GN:avn]
Gene
Avin_44580  nudix hydrolase, YffH family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Avin_05490  NUDIX hydrolase [KO:K08312] [EC:3.6.1.-]
Avin_02910  algC; Phosphomannomutase/phosphoglucomutase AlgC [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Avin_41520  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Avin_46210  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Avin_34150  purF; Amidophosphoribosyl transferase [KO:K00764] [EC:2.4.2.14]
Avin_06880  purD; Phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
Avin_36900  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Avin_39610  purT; Phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
Avin_39660  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Avin_36890  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Avin_01200  purK; Phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Avin_01190  purE; 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase [KO:K01588] [EC:5.4.99.18]
Avin_35320  purC; SAICAR synthetase [KO:K01923] [EC:6.3.2.6]
Avin_28380  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Avin_06890  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Avin_00130  5-nucleotidase/phosphoesterase [KO:K01081] [EC:3.1.3.5]
Avin_38710  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Avin_05480  HAD-superfamily hydrolase, subfamily IA, variant 3 [KO:K20881] [EC:3.1.3.-]
Avin_29860  Conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Avin_11950  Conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Avin_41350  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Avin_39730  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
Avin_40330  ndk; Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Avin_03010  rdgB; non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Avin_47930  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
Avin_22290  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
Avin_22280  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
Avin_39720  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
Avin_33160  Glutamine amidotransferase class-I protein [KO:K01951] [EC:6.3.5.2]
Avin_22260  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Avin_02830  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
Avin_00810  ribonucleotide-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Avin_33290  nrdA; ribonucleoside-diphosphate reductase, alpha subunit precursor [KO:K00525] [EC:1.17.4.1]
Avin_33300  nrdB; Ribonucleoside-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
Avin_18960  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Avin_02810  relA; guanosine 3,5-bis-pyrophosphate (ppGpp) synthetase, RelA/SpoT protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Avin_47430  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Avin_37060  ilvM; RelA/SpoT protein [KO:K00951] [EC:2.7.6.5]
Avin_32750  cyaB; Adenylate cyclase protein [KO:K01768] [EC:4.6.1.1]
Avin_07600  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Avin_09370  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Avin_27090  Conserved hypothetical protein 730 [KO:K06966] [EC:3.2.2.10 3.2.2.-]
Avin_22300  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
Avin_39280  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Avin_36950  mazG; Nucleotide pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
Avin_43500  cyclic 3,5-nucleotide monophosphate metallophosphodiesterase [KO:K03651] [EC:3.1.4.53]
Avin_46850  apaH; bis(5-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
Avin_12980  cysN; Adenylylsulfate kinase/Sulfate Adenylyltransferase subunit 1 [KO:K00955] [EC:2.7.7.4 2.7.1.25]
Avin_24694  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Avin_16180  cysC1; Adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Avin_00500  cysC2; Adenylylsulfate kinase, C-terminal domain protein [KO:K00860] [EC:2.7.1.25]
Avin_12970  cysD; Phosphoadenosine phosphosulfate reductase/sulfate adenyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Avin_21140  hydroxyisourate hydrolase, transthyretin family protein [KO:K07127] [EC:3.5.2.17]
Avin_21130  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
Avin_21110  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
Avin_21100  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Avin_09880  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Avin_09890  ureB; Urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Avin_09900  ureA; Urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
avn00030  Pentose phosphate pathway
avn00220  Arginine biosynthesis
avn00250  Alanine, aspartate and glutamate metabolism
avn00260  Glycine, serine and threonine metabolism
avn00340  Histidine metabolism
avn00630  Glyoxylate and dicarboxylate metabolism
avn00730  Thiamine metabolism
avn00740  Riboflavin metabolism
avn00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system