KEGG   PATHWAY: bpsh00630
Entry
bpsh00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia pseudomallei HBPUB10134a
Class
Metabolism; Carbohydrate metabolism
Pathway map
bpsh00630  Glyoxylate and dicarboxylate metabolism
bpsh00630

Module
bpsh_M00012  Glyoxylate cycle [PATH:bpsh00630]
bpsh_M00621  Glycine cleavage system [PATH:bpsh00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia pseudomallei HBPUB10134a [GN:bpsh]
Gene
DR55_1000  [KO:K03781] [EC:1.11.1.6]
DR55_1010  [KO:K00626] [EC:2.3.1.9]
DR55_1143  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DR55_1144  gcvH; glycine cleavage system H protein [KO:K02437]
DR55_1145  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
DR55_1458  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DR55_1585  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DR55_1673  [KO:K11473] [EC:1.1.99.14]
DR55_1674  [KO:K11472] [EC:1.1.99.14]
DR55_1675  [KO:K00104] [EC:1.1.99.14]
DR55_1760  [KO:K00600] [EC:2.1.2.1]
DR55_1979  [KO:K00126] [EC:1.17.1.9]
DR55_1980  [KO:K00123] [EC:1.17.1.9]
DR55_1981  [KO:K00124]
DR55_1982  [KO:K00127]
DR55_2057  [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR55_2066  [KO:K01091] [EC:3.1.3.18]
DR55_2182  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
DR55_2184  [KO:K01915] [EC:6.3.1.2]
DR55_2202  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
DR55_2222  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR55_231  [KO:K01647] [EC:2.3.3.1]
DR55_2392  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DR55_2396  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
DR55_2512  [KO:K00865] [EC:2.7.1.165]
DR55_2566  [KO:K00042] [EC:1.1.1.60]
DR55_2567  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DR55_2568  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DR55_2650  [KO:K00626] [EC:2.3.1.9]
DR55_2651  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DR55_2655  [KO:K00626] [EC:2.3.1.9]
DR55_2693  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR55_272  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DR55_3015  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR55_3216  [KO:K01895] [EC:6.2.1.1]
DR55_3542  acnA; aconitate hydratase 1 [KO:K27802]
DR55_3546  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DR55_3553  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DR55_3604  [KO:K00123] [EC:1.17.1.9]
DR55_3605  [KO:K00123] [EC:1.17.1.9]
DR55_3606  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
DR55_3607  [KO:K00127]
DR55_3808  [KO:K05825] [EC:2.6.1.-]
DR55_4340  [KO:K03781] [EC:1.11.1.6]
DR55_4369  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
DR55_4734  [KO:K01895] [EC:6.2.1.1]
DR55_4793  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR55_4804  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
DR55_4881  [KO:K01915] [EC:6.3.1.2]
DR55_4964  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DR55_50  [KO:K05825] [EC:2.6.1.-]
DR55_5154  [KO:K01659] [EC:2.3.3.5]
DR55_5238  [KO:K00865] [EC:2.7.1.165]
DR55_534  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR55_5360  [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR55_5460  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR55_5519  [KO:K03781] [EC:1.11.1.6]
DR55_5819  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
DR55_714  [KO:K00626] [EC:2.3.1.9]
DR55_751  ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bpsh00010  Glycolysis / Gluconeogenesis
bpsh00020  Citrate cycle (TCA cycle)
bpsh00030  Pentose phosphate pathway
bpsh00053  Ascorbate and aldarate metabolism
bpsh00071  Fatty acid degradation
bpsh00230  Purine metabolism
bpsh00250  Alanine, aspartate and glutamate metabolism
bpsh00260  Glycine, serine and threonine metabolism
bpsh00270  Cysteine and methionine metabolism
bpsh00620  Pyruvate metabolism
bpsh00710  Carbon fixation by Calvin cycle
bpsh00750  Vitamin B6 metabolism
bpsh00910  Nitrogen metabolism
KO pathway
ko00630   

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