KEGG   PATHWAY: cda00230
Entry
cda00230                    Pathway                                
Name
Purine metabolism - Corynebacterium diphtheriae HC04
Class
Metabolism; Nucleotide metabolism
Pathway map
cda00230  Purine metabolism
cda00230

Module
cda_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cda00230]
cda_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cda00230]
cda_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cda00230]
cda_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cda00230]
cda_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cda00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium diphtheriae HC04 [GN:cda]
Gene
CDHC04_0187  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
CDHC04_0248  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CDHC04_0371  [KO:K21636] [EC:1.1.98.6]
CDHC04_0444  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CDHC04_0485  guaB; inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CDHC04_0486  [KO:K00088] [EC:1.1.1.205]
CDHC04_0499  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CDHC04_0545  [KO:K01488] [EC:3.5.4.4]
CDHC04_0568  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
CDHC04_0569  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
CDHC04_0759  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CDHC04_0760  purH; bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CDHC04_0818  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CDHC04_0835  ppx2; putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CDHC04_1196  [KO:K01951] [EC:6.3.5.2]
CDHC04_1238  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CDHC04_1273  rel; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CDHC04_1274  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CDHC04_1309  [KO:K19710] [EC:2.7.7.53]
CDHC04_1506  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CDHC04_1591  [KO:K02566] [EC:3.1.3.5]
CDHC04_1600  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CDHC04_1650  iunH; inosine-uridine preferring nucleoside hydrolase [KO:K25589]
CDHC04_1676  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CDHC04_1731  [KO:K01519] [EC:3.6.1.66]
CDHC04_1752  nrdF1; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CDHC04_1755  nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CDHC04_1770  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CDHC04_1803  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CDHC04_1804  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CDHC04_1809  nrdF2; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CDHC04_1815  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
CDHC04_1816  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CDHC04_1821  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
CDHC04_1876  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CDHC04_1916  hpt2; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CDHC04_1979  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CDHC04_1985  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CDHC04_2054  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CDHC04_2240  [KO:K01239] [EC:3.2.2.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cda00030  Pentose phosphate pathway
cda00220  Arginine biosynthesis
cda00250  Alanine, aspartate and glutamate metabolism
cda00260  Glycine, serine and threonine metabolism
cda00340  Histidine metabolism
cda00630  Glyoxylate and dicarboxylate metabolism
cda00730  Thiamine metabolism
cda00740  Riboflavin metabolism
cda00790  Folate biosynthesis
KO pathway
ko00230   

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