KEGG   PATHWAY: cvb00230
Entry
cvb00230                    Pathway                                
Name
Purine metabolism - Congregibacter variabilis
Class
Metabolism; Nucleotide metabolism
Pathway map
cvb00230  Purine metabolism
cvb00230

Module
cvb_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cvb00230]
cvb_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cvb00230]
cvb_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cvb00230]
cvb_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cvb00230]
cvb_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cvb00230]
cvb_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cvb00230]
cvb_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cvb00230]
Other DBs
GO: 0006163 0042278
Organism
Congregibacter variabilis [GN:cvb]
Gene
R0135_00355  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
R0135_00405  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
R0135_00410  [KO:K01488] [EC:3.5.4.4]
R0135_00425  [KO:K21053] [EC:3.5.4.2]
R0135_00815  [KO:K01768] [EC:4.6.1.1]
R0135_00830  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
R0135_00835  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
R0135_00910  [KO:K00948] [EC:2.7.6.1]
R0135_00935  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
R0135_00965  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
R0135_01475  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
R0135_01840  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
R0135_01845  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
R0135_01850  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
R0135_01900  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
R0135_02540  [KO:K01081] [EC:3.1.3.5]
R0135_02605  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
R0135_02715  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
R0135_02720  [KO:K01483] [EC:4.3.2.3]
R0135_02725  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
R0135_02730  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
R0135_02735  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
R0135_02745  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
R0135_02750  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
R0135_02770  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
R0135_02775  [KO:K01429] [EC:3.5.1.5]
R0135_02780  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
R0135_03835  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
R0135_04470  [KO:K01589] [EC:6.3.4.18]
R0135_04475  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
R0135_06550  [KO:K01768] [EC:4.6.1.1]
R0135_07045  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
R0135_07050  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
R0135_07555  [KO:K00948] [EC:2.7.6.1]
R0135_08535  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
R0135_09370  [KO:K00525] [EC:1.17.4.1]
R0135_09375  [KO:K00526] [EC:1.17.4.1]
R0135_09965  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
R0135_11395  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
R0135_11475  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
R0135_11515  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
R0135_11525  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
R0135_12165  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
R0135_13370  [KO:K01486] [EC:3.5.4.2]
R0135_14370  [KO:K01525] [EC:3.6.1.41]
R0135_14555  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
R0135_14560  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
R0135_15000  [KO:K01939] [EC:6.3.4.4]
R0135_15540  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
R0135_16965  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
R0135_17050  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
R0135_17415  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
R0135_17420  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cvb00030  Pentose phosphate pathway
cvb00220  Arginine biosynthesis
cvb00250  Alanine, aspartate and glutamate metabolism
cvb00260  Glycine, serine and threonine metabolism
cvb00340  Histidine metabolism
cvb00630  Glyoxylate and dicarboxylate metabolism
cvb00730  Thiamine metabolism
cvb00740  Riboflavin metabolism
cvb00790  Folate biosynthesis
KO pathway
ko00230   

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