KEGG   PATHWAY: dlc00230
Entry
dlc00230                    Pathway                                
Name
Purine metabolism - Dickeya lacustris
Class
Metabolism; Nucleotide metabolism
Pathway map
dlc00230  Purine metabolism
dlc00230

Module
dlc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:dlc00230]
dlc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dlc00230]
dlc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:dlc00230]
Other DBs
GO: 0006163 0042278
Organism
Dickeya lacustris [GN:dlc]
Gene
O1Q98_00115  cyaB; class IV adenylate cyclase [KO:K05873] [EC:4.6.1.1]
O1Q98_01850  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
O1Q98_03130  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
O1Q98_03525  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
O1Q98_04660  [KO:K01241] [EC:3.2.2.4]
O1Q98_05625  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
O1Q98_05710  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
O1Q98_05865  [KO:K01951] [EC:6.3.5.2]
O1Q98_06220  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
O1Q98_06265  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
O1Q98_06270  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
O1Q98_06405  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
O1Q98_06470  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
O1Q98_06625  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
O1Q98_06835  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
O1Q98_06935  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
O1Q98_07070  yfiH; purine nucleoside phosphorylase YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
O1Q98_08365  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
O1Q98_08370  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
O1Q98_08970  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
O1Q98_09675  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
O1Q98_09685  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
O1Q98_10200  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
O1Q98_10205  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
O1Q98_11395  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
O1Q98_11405  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
O1Q98_12800  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
O1Q98_13250  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
O1Q98_13260  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
O1Q98_14135  [KO:K01939] [EC:6.3.4.4]
O1Q98_14270  yjjX; inosine/xanthosine triphosphatase [KO:K01529]
O1Q98_14450  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
O1Q98_15255  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
O1Q98_15395  [KO:K01119] [EC:3.1.4.16 3.1.3.6]
O1Q98_15585  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
O1Q98_15590  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
O1Q98_15665  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
O1Q98_15670  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
O1Q98_15675  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
O1Q98_15870  [KO:K16841] [EC:5.1.99.3]
O1Q98_15875  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
O1Q98_15895  [KO:K22601] [EC:2.1.3.5]
O1Q98_15905  [KO:K22602] [EC:3.5.1.126]
O1Q98_15940  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
O1Q98_16015  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
O1Q98_16705  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
O1Q98_16960  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
O1Q98_17320  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
O1Q98_17345  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
O1Q98_17360  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
O1Q98_17405  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
O1Q98_17410  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
O1Q98_17550  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
O1Q98_17555  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
O1Q98_17605  [KO:K01923] [EC:6.3.2.6]
O1Q98_17910  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
dlc00030  Pentose phosphate pathway
dlc00220  Arginine biosynthesis
dlc00250  Alanine, aspartate and glutamate metabolism
dlc00260  Glycine, serine and threonine metabolism
dlc00340  Histidine metabolism
dlc00630  Glyoxylate and dicarboxylate metabolism
dlc00730  Thiamine metabolism
dlc00740  Riboflavin metabolism
dlc00790  Folate biosynthesis
KO pathway
ko00230   

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