KEGG   PATHWAY: dsi00350
Entry
dsi00350                    Pathway                                
Name
Tyrosine metabolism - Drosophila simulans
Class
Metabolism; Amino acid metabolism
Pathway map
dsi00350  Tyrosine metabolism
dsi00350

Module
dsi_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:dsi00350]
Other DBs
GO: 0006570
Organism
Drosophila simulans [GN:dsi]
Gene
Dsimw501_GD10252  Dsim_GD10252; uncharacterized protein, isoform K [KO:K00129] [EC:1.2.1.5]
Dsimw501_GD10312  Dsim_GD10312; uncharacterized protein, isoform C [KO:K22329] [EC:4.1.1.25]
Dsimw501_GD10313  Dsim_GD10313; uncharacterized protein [KO:K22329] [EC:4.1.1.25]
Dsimw501_GD11164  Dsim_GD11164; uncharacterized protein, isoform A [KO:K14454] [EC:2.6.1.1]
Dsimw501_GD11733  Dsim_GD11733; uncharacterized protein [KO:K00505] [EC:1.14.18.1]
Dsimw501_GD12185  Dsim_GD12185; uncharacterized protein [KO:K00457] [EC:1.13.11.27]
Dsimw501_GD13115  Dsim_GD13115; uncharacterized protein [KO:K00501] [EC:1.14.16.2]
Dsimw501_GD13297  Dsim_GD13297; uncharacterized protein [KO:K01555] [EC:3.7.1.2]
Dsimw501_GD16874  Dsim_Tbh; Tbh, isoform B [KO:K00503] [EC:1.14.17.1]
Dsimw501_GD17166  Dsim_GD17166; uncharacterized protein, isoform C [KO:K00815] [EC:2.6.1.5]
Dsimw501_GD19399  Dsim_GD19399; uncharacterized protein [KO:K01557] [EC:3.7.1.5]
Dsimw501_GD20528  Dsim_GD20528; uncharacterized protein [KO:K22203] [EC:5.3.3.12]
Dsimw501_GD20529  Dsim_GD20529; uncharacterized protein [KO:K22203] [EC:5.3.3.12]
Dsimw501_GD20694  Dsim_GD20694; uncharacterized protein [KO:K00121] [EC:1.1.1.284 1.1.1.1]
Dsimw501_GD20795  Dsim_GD20795; uncharacterized protein, isoform A [KO:K01800] [EC:5.2.1.2]
Dsimw501_GD20796  Dsim_GD20796; uncharacterized protein [KO:K01800] [EC:5.2.1.2]
Dsimw501_GD21778  Dsim_Ddc; Ddc, isoform A [KO:K01593] [EC:4.1.1.28 4.1.1.105]
Dsimw501_GD22881  Dsim_GD22881; uncharacterized protein, isoform A [KO:K14455] [EC:2.6.1.1]
Dsimw501_GD23768  Dsim_GD23768; uncharacterized protein [KO:K00451] [EC:1.13.11.5]
Dsimw501_GD23968  Dsim_Adh; alcohol dehydrogenase [KO:K00001] [EC:1.1.1.1]
Dsimw501_GD24184  Dsim_amd; alpha methyl dopa-resistant, isoform A [KO:K01618] [EC:4.1.1.107]
Dsimw501_GD25430  Dsim_GD25430; uncharacterized protein [KO:K00505] [EC:1.14.18.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
dsi00020  Citrate cycle (TCA cycle)
dsi00360  Phenylalanine metabolism
dsi00400  Phenylalanine, tyrosine and tryptophan biosynthesis
dsi00620  Pyruvate metabolism
dsi00650  Butanoate metabolism
KO pathway
ko00350   

DBGET integrated database retrieval system