KEGG   PATHWAY: eck00330
Entry
eck00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli 55989 (EAEC)
Class
Metabolism; Amino acid metabolism
Pathway map
eck00330  Arginine and proline metabolism
eck00330

Module
eck_M00015  Proline biosynthesis, glutamate => proline [PATH:eck00330]
eck_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:eck00330]
eck_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:eck00330]
eck_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:eck00330]
eck_M00970  Proline degradation, proline => glutamate [PATH:eck00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli 55989 (EAEC) [GN:eck]
Gene
EC55989_0113  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
EC55989_0114  speE; spermidine synthase (putrescine aminopropyltransferase) [KO:K00797] [EC:2.5.1.16]
EC55989_0266  proB; gamma-glutamate kinase [KO:K00931] [EC:2.7.2.11]
EC55989_0267  proA; gamma-glutamylphosphate reductase [KO:K00147] [EC:1.2.1.41]
EC55989_0344  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
EC55989_0395  proC; pyrroline-5-carboxylate reductase, NAD(P)-binding [KO:K00286] [EC:1.5.1.2]
EC55989_0677  speF; ornithine decarboxylase isozyme, inducible [KO:K01581] [EC:4.1.1.17]
EC55989_0977  aspC; aspartate aminotransferase, PLP-dependent [KO:K00813] [EC:2.6.1.1]
EC55989_1125  putA; fused DNA-binding transcriptional regulator; proline dehydrogenase; pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
EC55989_1459  puuA; gamma-Glu-putrescine synthase [KO:K09470] [EC:6.3.1.11]
EC55989_1460  puuD; gamma-Glu-GABA hydrolase [KO:K09473] [EC:3.5.1.94]
EC55989_1462  puuC; gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, NAD(P)H-dependent [KO:K09472] [EC:1.2.1.99]
EC55989_1463  puuB; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding [KO:K09471] [EC:1.4.3.-]
EC55989_1576  ydcW; medium chain aldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
EC55989_1749  speG; spermidine N1-acetyltransferase [KO:K00657] [EC:2.3.1.57]
EC55989_1912  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
EC55989_1913  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
EC55989_1914  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
EC55989_1915  astA; arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
EC55989_1916  astC; succinylornithine transaminase, PLP-dependent [KO:K00840] [EC:2.6.1.81]
EC55989_3229  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
EC55989_3231  speA; biosynthetic arginine decarboxylase, PLP-binding [KO:K01585] [EC:4.1.1.19]
EC55989_3258  speC; ornithine decarboxylase, constitutive [KO:K01581] [EC:4.1.1.17]
EC55989_3487  ygjG; putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent [KO:K09251] [EC:2.6.1.82]
EC55989_4608  adiA; biodegradative arginine decarboxylase [KO:K01584] [EC:4.1.1.19]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
eck00020  Citrate cycle (TCA cycle)
eck00220  Arginine biosynthesis
eck00250  Alanine, aspartate and glutamate metabolism
eck00260  Glycine, serine and threonine metabolism
eck00270  Cysteine and methionine metabolism
eck00310  Lysine degradation
eck00410  beta-Alanine metabolism
eck00470  D-Amino acid metabolism
eck00480  Glutathione metabolism
eck00630  Glyoxylate and dicarboxylate metabolism
eck00650  Butanoate metabolism
eck00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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