KEGG   PATHWAY: eoi00620
Entry
eoi00620                    Pathway                                
Name
Pyruvate metabolism - Escherichia coli O111:H- 11128 (EHEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
eoi00620  Pyruvate metabolism
eoi00620

Module
eoi_M00168  CAM (Crassulacean acid metabolism), dark [PATH:eoi00620]
eoi_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:eoi00620]
eoi_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:eoi00620]
Other DBs
GO: 0006090
Organism
Escherichia coli O111:H- 11128 (EHEC) [GN:eoi]
Gene
ECO111_0077  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
ECO111_0115  aceE; pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding [KO:K00163] [EC:1.2.4.1]
ECO111_0116  aceF; pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2 [KO:K00627] [EC:2.3.1.12]
ECO111_0117  lpd; lipoamide dehydrogenase, E3 component [KO:K00382] [EC:1.8.1.4]
ECO111_0186  accA; acetyl-CoA carboxylase, carboxytransferase component, alpha subunit [KO:K01962] [EC:6.4.1.2 2.1.3.15]
ECO111_0209  gloB; predicted hydroxyacylglutathione hydrolase [KO:K01069] [EC:3.1.2.6]
ECO111_0364  yahK; predicted oxidoreductase, Zn-dependent and NAD(P)-binding [KO:K13979] [EC:1.1.1.2]
ECO111_0387  mhpF; acetaldehyde-CoA dehydrogenase II, NAD-binding [KO:K04073] [EC:1.2.1.10]
ECO111_0392  frmA; alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
ECO111_0940  poxB; pyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding [KO:K00156] [EC:1.2.5.1]
ECO111_0971  pflB; pyruvate formate lyase I [KO:K00656] [EC:2.3.1.54]
ECO111_0995  ycbL; predicted metal-binding enzyme [KO:K01069] [EC:3.1.2.6]
ECO111_1036  yccX; predicted acylphosphatase [KO:K01512] [EC:3.6.1.7]
ECO111_1310  ycdW; 2-ketoacid reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
ECO111_1568  adhE; fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [KO:K04072] [EC:1.2.1.10 1.1.1.1]
ECO111_1770  ydbK; fused predicted pyruvate-flavodoxin oxidoreductase: conserved protein/conserved protein/FeS binding protein [KO:K03737] [EC:1.2.7.1 1.2.8.1]
ECO111_1773  ldhA; fermentative D-lactate dehydrogenase, NAD-dependent [KO:K03778] [EC:1.1.1.28]
ECO111_1868  adhP; alcohol dehydrogenase, 1-propanol preferring [KO:K13953] [EC:1.1.1.1]
ECO111_1869  sfcA; malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
ECO111_2080  fumC; fumarate hydratase, aerobic, class II [KO:K01679] [EC:4.2.1.2]
ECO111_2081  fumA; fumarate hydratase, aerobic, class I [KO:K01676] [EC:4.2.1.2]
ECO111_2121  gloA; glyoxalase I, Ni-dependent [KO:K01759] [EC:4.4.1.5]
ECO111_2144  ydhZ; conserved predicted protein [KO:K01675]
ECO111_2145  pykF; pyruvate kinase I [KO:K00873] [EC:2.7.1.40]
ECO111_2172  pps; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
ECO111_2362  pykA; pyruvate kinase II [KO:K00873] [EC:2.7.1.40]
ECO111_2546  hchA; Hsp31 molecular chaperone [KO:K05523] [EC:4.2.1.130 3.5.1.124]
ECO111_2851  dld; D-lactate dehydrogenase, FAD-binding, NADH independent [KO:K03777] [EC:1.1.5.12]
ECO111_2947  mqo; malate dehydrogenase Mqo, FAD/NAD(P)-binding domain [KO:K00116] [EC:1.1.5.4]
ECO111_3044  ackA; acetate kinase A and propionate kinase 2 [KO:K00925] [EC:2.7.2.1]
ECO111_3045  pta; phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
ECO111_3064  accD; acetyl-CoA carboxylase beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
ECO111_3173  eutG; predicted alcohol dehydrogenase [KO:K04022]
ECO111_3175  eutE; predicted aldehyde dehydrogenase EutE [KO:K04021]
ECO111_3178  eutI; predicted phosphotransacetylase subunit [KO:K04020]
ECO111_3183  maeB; fused malic enzyme and predicted oxidoreductase/predicted phosphotransacetylase [KO:K00029] [EC:1.1.1.40]
ECO111_3573  yqeF; predicted acyltransferase [KO:K00626] [EC:2.3.1.9]
ECO111_3670  yggD; predicted DNA-binding transcriptional regulator [KO:K01774]
ECO111_3797  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
ECO111_3938  tdcE; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase [KO:K00656] [EC:2.3.1.54]
ECO111_4056  mdh; malate dehydrogenase, NAD(P)-binding [KO:K00024] [EC:1.1.1.37]
ECO111_4074  accB; acetyl CoA carboxylase, BCCP subunit [KO:K02160]
ECO111_4075  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
ECO111_4212  pck; phosphoenolpyruvate carboxykinase [KO:K01610] [EC:4.1.1.49]
ECO111_4373  tiaE; 2-keto-D-gluconate reductase TiaE [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
ECO111_4408  aldB; aldehyde dehydrogenase B [KO:K00138] [EC:1.2.1.-]
ECO111_4409  yiaY; predicted Fe-containing alcohol dehydrogenase [KO:K13954] [EC:1.1.1.1]
ECO111_4430  lldD; L-lactate dehydrogenase LldD, FMN-linked [KO:K00101] [EC:1.1.2.3]
ECO111_4725  [KO:K13954] [EC:1.1.1.1]
ECO111_4781  ppc; phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
ECO111_4826  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
ECO111_4945  acs; acetyl-CoA synthetase Acs [KO:K01895] [EC:6.2.1.1]
ECO111_4992  fumB; anaerobic class I fumarate hydratase [KO:K01676] [EC:4.2.1.2]
ECO111_5057  frdA; fumarate reductase catalytic and NAD/flavoprotein subunit FrdA, anaerobic [KO:K00244] [EC:1.3.5.1]
ECO111_5058  frdB; fumarate reductase, Fe-S subunit FrdB [KO:K00245] [EC:1.3.5.1]
ECO111_5059  frdC; fumarate reductase, membrane anchor subunit FrdC, anaerobic [KO:K00246]
ECO111_5060  frdD; fumarate reductase, membrane anchor subunit FrdD, anaerobic [KO:K00247]
ECO111_5148  yjgB; predicted alcohol dehydrogenase, Zn-dependent and NAD(P)-binding [KO:K12957] [EC:1.1.1.2 1.1.1.183]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
eoi00010  Glycolysis / Gluconeogenesis
eoi00020  Citrate cycle (TCA cycle)
eoi00061  Fatty acid biosynthesis
eoi00250  Alanine, aspartate and glutamate metabolism
eoi00260  Glycine, serine and threonine metabolism
eoi00290  Valine, leucine and isoleucine biosynthesis
eoi00300  Lysine biosynthesis
eoi00630  Glyoxylate and dicarboxylate metabolism
eoi00640  Propanoate metabolism
eoi00650  Butanoate metabolism
eoi00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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