KEGG   PATHWAY: etr00230
Entry
etr00230                    Pathway                                
Name
Purine metabolism - Edwardsiella piscicida EIB202
Class
Metabolism; Nucleotide metabolism
Pathway map
etr00230  Purine metabolism
etr00230

Module
etr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:etr00230]
etr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:etr00230]
etr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:etr00230]
etr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:etr00230]
etr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:etr00230]
etr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:etr00230]
etr_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:etr00230]
Other DBs
GO: 0006163 0042278
Organism
Edwardsiella piscicida EIB202 [GN:etr]
Gene
ETAE_0029  spoT; guanosine polyphosphate pyrophosphohydrolase/synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ETAE_0031  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ETAE_0097  gppA; guanosine pentaphosphate phosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ETAE_0119  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ETAE_0185  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
ETAE_0186  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ETAE_0192  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ETAE_0193  icc; cyclic 3,5-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ETAE_0272  yggV; putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
ETAE_0358  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ETAE_0423  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ETAE_0488  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ETAE_0489  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ETAE_0544  [KO:K01529]
ETAE_0587  xdhC; xanthine dehydrogenase, Fe-S binding subunit [KO:K13480]
ETAE_0588  xdhB; xanthine dehydrogenase, FAD-binding subunit [KO:K13479] [EC:1.17.1.4]
ETAE_0589  xdhA; xanthine dehydrogenase subunit XdhA [KO:K00087] [EC:1.17.1.4]
ETAE_0598  apaH; diadenosinetetraphosphatase [KO:K01525] [EC:3.6.1.41]
ETAE_0651  guaC; guanosine 5-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
ETAE_0670  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ETAE_0723  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ETAE_0774  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ETAE_0793  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ETAE_0853  guaD1; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ETAE_1019  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ETAE_1025  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ETAE_1027  [KO:K00892] [EC:2.7.1.73]
ETAE_1034  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ETAE_1057  [KO:K07127] [EC:3.5.2.17]
ETAE_1072  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ETAE_1082  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ETAE_1085  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ETAE_1086  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ETAE_1098  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ETAE_1402  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ETAE_1705  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ETAE_1838  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
ETAE_1877  [KO:K01241] [EC:3.2.2.4]
ETAE_2056  purB2; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ETAE_2338  nrdA; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
ETAE_2339  nrdB; ribonucleotide reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
ETAE_2392  [KO:K08722] [EC:3.1.3.89]
ETAE_2409  [KO:K00764] [EC:2.4.2.14]
ETAE_2596  [KO:K01120] [EC:3.1.4.17]
ETAE_2605  [KO:K01835] [EC:5.4.2.2]
ETAE_2621  nagD; UMP phosphatase [KO:K02566] [EC:3.1.3.5]
ETAE_2700  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
ETAE_2701  purK; phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
ETAE_2713  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ETAE_2714  relA; GDP/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
ETAE_2772  [KO:K01129] [EC:3.1.5.1]
ETAE_2779  xapA; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
ETAE_2786  guaA; GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
ETAE_2787  guaB; inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ETAE_2806  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ETAE_2830  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ETAE_2876  surE; stationary phase survival protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ETAE_3164  guaD2; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ETAE_3174  yqeA; carbamate kinase [KO:K00926] [EC:2.7.2.2]
ETAE_3268  [KO:K08312] [EC:3.6.1.-]
ETAE_3270  [KO:K20881] [EC:3.1.3.-]
ETAE_3544  adeC; adenine deaminase [KO:K01486] [EC:3.5.4.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
etr00030  Pentose phosphate pathway
etr00220  Arginine biosynthesis
etr00250  Alanine, aspartate and glutamate metabolism
etr00260  Glycine, serine and threonine metabolism
etr00340  Histidine metabolism
etr00630  Glyoxylate and dicarboxylate metabolism
etr00730  Thiamine metabolism
etr00740  Riboflavin metabolism
etr00790  Folate biosynthesis
KO pathway
ko00230   

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