KEGG   Homo sapiens (human): 22801
Entry
22801             CDS       T01001                                 
Symbol
ITGA11, HsT18964
Name
(RefSeq) integrin subunit alpha 11
  KO
K06587  integrin alpha 11
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04518  Integrin signaling
hsa04810  Regulation of actin cytoskeleton
hsa04820  Cytoskeleton in muscle cells
hsa05165  Human papillomavirus infection
hsa05410  Hypertrophic cardiomyopathy
hsa05412  Arrhythmogenic right ventricular cardiomyopathy
hsa05414  Dilated cardiomyopathy
Network
nt06167  Human cytomegalovirus (HCMV)
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
nt06548  Integrin signaling
  Element
N00393  ITGA/B-RhoGAP-RhoA signaling pathway
N00951  ITGA/B-RHOG-RAC signaling pathway
N01068  ITGA/B-FAK-RAC signaling pathway
N01070  ITGA/B-FAK-CDC42 signaling pathway
N01072  ITGA/B-RhoGEF-RhoA signaling pathway
N01080  ITGA/B-TALIN/VINCULIN signaling pathway
N01996  Integrin alpha11beta1 signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    22801 (ITGA11)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    22801 (ITGA11)
   04518 Integrin signaling
    22801 (ITGA11)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    22801 (ITGA11)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    22801 (ITGA11)
   04810 Regulation of actin cytoskeleton
    22801 (ITGA11)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    22801 (ITGA11)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    22801 (ITGA11)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    22801 (ITGA11)
   05414 Dilated cardiomyopathy
    22801 (ITGA11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    22801 (ITGA11)
Cell adhesion molecules [BR:hsa04515]
 Integrins
  Integrin alpha subunits
   22801 (ITGA11)
SSDB
Motif
Pfam: VWA FG-GAP Integrin_A_Ig_1 VWA_2 Integrin_A_Ig_2 FG-GAP_3 FG-GAP_2 Integrin_A_Ig_3 DUF918
Other DBs
NCBI-GeneID: 22801
NCBI-ProteinID: NP_001004439
OMIM: 604789
HGNC: 6136
Ensembl: ENSG00000137809
UniProt: Q9UKX5 B3KTN6
LinkDB
Position
15:complement(68296532..68432163)
AA seq 1188 aa
MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA
PLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLA
CSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVE
VQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTET
RTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVL
GYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNET
SFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN
HGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYF
GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNA
RFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATG
LQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCK
RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAV
LLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNG
CNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAV
EATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFF
RAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFT
RSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL
KLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEI
NFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQV
PIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE
NT seq 3567 nt   +upstreamnt  +downstreamnt
atggacctgcccaggggcctggtggtggcctgggcgctcagcctgtggccagggttcacg
gacaccttcaacatggacaccaggaagccccgggtcatccctggctccaggaccgccttc
tttggctacacagtgcagcagcacgacatcagtggcaataagtggctggtcgtgggcgcc
ccactggaaaccaatggctaccagaagacgggagacgtgtacaagtgtccagtgatccac
gggaactgcaccaaactcaacctgggaagggtcaccctgtccaacgtgtccgagcggaaa
gacaacatgcgcctcggccttagtctcgccaccaaccccaaggacaacagcttcctggcc
tgcagccccctctggtctcatgagtgtgggagctcctactacaccacagggatgtgttca
agagtcaactccaacttcaggttctccaagaccgtggccccagctctccaaaggtgccag
acctacatggacatcgtcattgtcctggatggctccaacagcatctacccctgggtggag
gttcagcacttcctcatcaacatcctgaaaaagttttacattggcccagggcagatccag
gttggagttgtgcagtatggcgaagatgtggtgcatgagtttcacctcaacgactacagg
tctgtaaaagatgtggtggaagctgccagccacattgagcagagaggaggaacagagacc
cggacggcatttggcattgaatttgcacgctcagaggctttccagaagggtggaaggaaa
ggagccaagaaggtgatgattgtcatcacagatggggagtcccacgacagcccagacctg
gagaaggtgatccagcaaagcgaaagagacaacgtaacaagatatgcggtggccgtcctg
ggctactacaaccgcagggggatcaatccagaaacttttctaaatgaaatcaaatacatc
gccagtgaccctgatgacaagcacttcttcaatgtcactgatgaggctgccttgaaggac
attgtcgatgccctgggggacagaatcttcagcctggaaggcaccaacaagaacgagacc
tcctttgggctggagatgtcacagacgggcttttcctcgcacgtggtggaggatggggtt
ctgctgggagccgtcggtgcctatgactggaatggagctgtgctaaaggagacgagtgcc
gggaaggtcattcctctccgcgagtcctacctgaaagagttccccgaggagctcaagaac
catggtgcatacctggggtacacagtcacatcggtcgtgtcctccaggcaggggcgggtg
tacgtggccggagccccccggttcaaccacacgggcaaggtcatcctgttcaccatgcac
aacaaccggagcctcaccatccaccaggctatgcggggccagcagataggctcttacttt
gggagtgaaatcacctcggtggacatcgacggcgacggcgtgactgatgtcctgctggtg
ggcgcacccatgtacttcaacgagggccgtgagcgaggcaaggtgtacgtctatgagctg
agacagaacctgtttgtttataacggaacgctaaaggattcacacagttaccagaatgcc
cgatttgggtcctccattgcctcagttcgagacctcaaccaggattcctacaatgacgtg
gtggtgggagcccccctggaggacaaccacgcaggagccatctacatcttccacggcttc
cgaggcagcatcctgaagacacctaagcagagaatcacagcctcagagctggctaccggc
ctccagtattttggctgcagcatccacgggcaattggacctcaatgaggatgggctcatc
gacctggcagtgggagcccttggcaacgctgtgattctgtggtcccgcccagtggttcag
atcaatgccagcctccactttgagccatccaagatcaacatcttccacagagactgcaag
cgcagtggcagggatgccacctgcctggccgccttcctctgcttcacgcccatcttcctg
gcaccccatttccaaacaacaactgttggcatcagatacaacgccaccatggatgagagg
cggtatacaccgagggcccacctggacgagggcggggaccgattcaccaacagagccgta
ctgctctcctccggccaggagctctgtgagcggatcaacttccatgtcctggacactgct
gactacgtgaagccagtgaccttctcagtcgagtattccctggaggaccctgaccatggc
cccatgctggacgacggctggcccaccactctcagagtctcggtgcccttctggaacggc
tgcaatgaggatgagcactgtgtccctgaccttgtgttggatgcccggagtgacctgccc
acggccatggagtactgccagagggtgctgaggaagcctgcgcaggactgctccgcatac
acgctgtccttcgacaccacagtcttcatcatagagagcacacgccagcgagtggcggtg
gaggccacactggagaacaggggcgagaacgcctacagcacggtcctaaatatctcgcag
tcagcaaacctgcagtttgccagcttgatccagaaggaggactcagacggtagcattgag
tgtgtgaacgaggagaggaggctccagaagcaagtctgcaacgtcagctatcccttcttc
cgggccaaggccaaggtggctttccgtcttgattttgagttcagcaaatccatcttccta
caccacctggagatcgagctcgctgcaggcagtgacagtaatgagcgggacagcaccaag
gaagacaacgtggcccccttacgcttccacctcaaatacgaggctgacgtcctcttcacc
aggagcagcagcctgagccactacgaggtcaagcccaacagctcgctggagagatacgat
ggtatcgggcctcccttcagctgcatcttcaggatccagaacttgggcttgttccccatc
cacgggatgatgatgaagatcaccattcccatcgccaccaggagcggcaaccgcctactg
aagctgagggacttcctcacggacgaggcgaacacgtcctgtaacatctggggcaatagc
actgagtaccggcccaccccagtggaggaagacttgcgtcgtgctccacagctgaatcac
agcaactctgatgtcgtctccatcaactgcaatatacggctggtccccaaccaggaaatc
aatttccatctactggggaacctgtggttgaggtccctaaaagcactcaagtacaaatcc
atgaaaatcatggtcaacgcagccttgcagaggcagttccacagccccttcatcttccgt
gaggaggatcccagccgccagatcgtgtttgagatctccaagcaagaggactggcaggtc
cccatctggatcattgtaggcagcaccctggggggcctcctactgctggccctgctggtc
ctggcactgtggaagctcggcttctttagaagtgccaggcgcaggagggagcctggtctg
gaccccacccccaaagtgctggagtga

KEGG   Homo sapiens (human): 3688
Entry
3688              CDS       T01001                                 
Symbol
ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
Name
(RefSeq) integrin subunit beta 1
  KO
K05719  integrin beta 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03271  Virion - Rotavirus
hsa04015  Rap1 signaling pathway
hsa04145  Phagosome
hsa04151  PI3K-Akt signaling pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04514  Cell adhesion molecule (CAM) interaction
hsa04517  IgSF CAM signaling
hsa04518  Integrin signaling
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04820  Cytoskeleton in muscle cells
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05133  Pertussis
hsa05135  Yersinia infection
hsa05140  Leishmaniasis
hsa05145  Toxoplasmosis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05205  Proteoglycans in cancer
hsa05222  Small cell lung cancer
hsa05410  Hypertrophic cardiomyopathy
hsa05412  Arrhythmogenic right ventricular cardiomyopathy
hsa05414  Dilated cardiomyopathy
Network
nt06167  Human cytomegalovirus (HCMV)
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
nt06539  Cytoskeleton in muscle cells
nt06546  IgSF CAM signaling
nt06548  Integrin signaling
  Element
N00393  ITGA/B-RhoGAP-RhoA signaling pathway
N00951  ITGA/B-RHOG-RAC signaling pathway
N01068  ITGA/B-FAK-RAC signaling pathway
N01070  ITGA/B-FAK-CDC42 signaling pathway
N01072  ITGA/B-RhoGEF-RhoA signaling pathway
N01080  ITGA/B-TALIN/VINCULIN signaling pathway
N01081  Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
N01815  Vinculin-talin-integrin macromolecular complex
N01921  Integrin alpha4beta1 signaling
N01957  JAM2 interactions
N01974  Integrin alpha9beta1 signaling
N01980  Integrin alpha5beta1 signaling
N01981  Integrin alpha8beta1 signaling
N01982  Integrin alphaVbeta1 signaling
N01987  Integrin alpha1beta1 signaling
N01988  Integrin alpha2beta1 signaling
N01989  Integrin alpha10beta1 signaling
N01990  Integrin alpha3beta1 signaling
N01991  Integrin alpha6beta1 signaling
N01996  Integrin alpha11beta1 signaling
N01997  Integrin alpha7beta1 signaling
Drug target
Bexotegrast: D12722
Carotegrast methyl: D09799<JP>
Valategrast hydrochloride: D10028
Volociximab: D06319
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03271 Virion - Rotavirus
    3688 (ITGB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    3688 (ITGB1)
   04151 PI3K-Akt signaling pathway
    3688 (ITGB1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3688 (ITGB1)
   04514 Cell adhesion molecule (CAM) interaction
    3688 (ITGB1)
   04517 IgSF CAM signaling
    3688 (ITGB1)
   04518 Integrin signaling
    3688 (ITGB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    3688 (ITGB1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3688 (ITGB1)
   04530 Tight junction
    3688 (ITGB1)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    3688 (ITGB1)
   04810 Regulation of actin cytoskeleton
    3688 (ITGB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    3688 (ITGB1)
   04670 Leukocyte transendothelial migration
    3688 (ITGB1)
  09158 Development and regeneration
   04360 Axon guidance
    3688 (ITGB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3688 (ITGB1)
   05205 Proteoglycans in cancer
    3688 (ITGB1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    3688 (ITGB1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3688 (ITGB1)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    3688 (ITGB1)
   05131 Shigellosis
    3688 (ITGB1)
   05135 Yersinia infection
    3688 (ITGB1)
   05133 Pertussis
    3688 (ITGB1)
   05100 Bacterial invasion of epithelial cells
    3688 (ITGB1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3688 (ITGB1)
   05140 Leishmaniasis
    3688 (ITGB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    3688 (ITGB1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    3688 (ITGB1)
   05414 Dilated cardiomyopathy
    3688 (ITGB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    3688 (ITGB1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3688 (ITGB1)
   04515 Cell adhesion molecules [BR:hsa04515]
    3688 (ITGB1)
   04090 CD molecules [BR:hsa04090]
    3688 (ITGB1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    3688 (ITGB1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3688 (ITGB1)
Cell adhesion molecules [BR:hsa04515]
 Integrins
  Integrin beta subunits
   3688 (ITGB1)
CD molecules [BR:hsa04090]
 Proteins
  3688 (ITGB1)
SSDB
Motif
Pfam: Integrin_beta Integrin_B_tail Integrin_b_cyt EGF_integrin PSI_integrin I-EGF_1 EGF_2 EGF_Teneurin vWA_SIBA-E
Other DBs
NCBI-GeneID: 3688
NCBI-ProteinID: NP_002202
OMIM: 135630
HGNC: 6153
Ensembl: ENSG00000150093
UniProt: P05556
Structure
LinkDB
Position
10:complement(32900318..32958230)
AA seq 798 aa
MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPT
SARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLV
LRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDF
RIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQR
ISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQ
CHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTL
SANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISI
GDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEG
NGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRK
RDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCE
ASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDT
CTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVEN
PECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGEN
PIYKSAVTTVVNPKYEGK
NT seq 2397 nt   +upstreamnt  +downstreamnt
atgaatttacaaccaattttctggattggactgatcagttcagtttgctgtgtgtttgct
caaacagatgaaaatagatgtttaaaagcaaatgccaaatcatgtggagaatgtatacaa
gcagggccaaattgtgggtggtgcacaaattcaacatttttacaggaaggaatgcctact
tctgcacgatgtgatgatttagaagccttaaaaaagaagggttgccctccagatgacata
gaaaatcccagaggctccaaagatataaagaaaaataaaaatgtaaccaaccgtagcaaa
ggaacagcagagaagctcaagccagaggatattactcagatccaaccacagcagttggtt
ttgcgattaagatcaggggagccacagacatttacattaaaattcaagagagctgaagac
tatcccattgacctctactaccttatggacctgtcttactcaatgaaagacgatttggag
aatgtaaaaagtcttggaacagatctgatgaatgaaatgaggaggattacttcggacttc
agaattggatttggctcatttgtggaaaagactgtgatgccttacattagcacaacacca
gctaagctcaggaacccttgcacaagtgaacagaactgcaccagcccatttagctacaaa
aatgtgctcagtcttactaataaaggagaagtatttaatgaacttgttggaaaacagcgc
atatctggaaatttggattctccagaaggtggtttcgatgccatcatgcaagttgcagtt
tgtggatcactgattggctggaggaatgttacacggctgctggtgttttccacagatgcc
gggtttcactttgctggagatgggaaacttggtggcattgttttaccaaatgatggacaa
tgtcacctggaaaataatatgtacacaatgagccattattatgattatccttctattgct
caccttgtccagaaactgagtgaaaataatattcagacaatttttgcagttactgaagaa
tttcagcctgtttacaaggagctgaaaaacttgatccctaagtcagcagtaggaacatta
tctgcaaattctagcaatgtaattcagttgatcattgatgcatacaattccctttcctca
gaagtcattttggaaaacggcaaattgtcagaaggcgtaacaataagttacaaatcttac
tgcaagaacggggtgaatggaacaggggaaaatggaagaaaatgttccaatatttccatt
ggagatgaggttcaatttgaaattagcataacttcaaataagtgtccaaaaaaggattct
gacagctttaaaattaggcctctgggctttacggaggaagtagaggttattcttcagtac
atctgtgaatgtgaatgccaaagcgaaggcatccctgaaagtcccaagtgtcatgaagga
aatgggacatttgagtgtggcgcgtgcaggtgcaatgaagggcgtgttggtagacattgt
gaatgcagcacagatgaagttaacagtgaagacatggatgcttactgcaggaaagaaaac
agttcagaaatctgcagtaacaatggagagtgcgtctgcggacagtgtgtttgtaggaag
agggataatacaaatgaaatttattctggcaaattctgcgagtgtgataatttcaactgt
gatagatccaatggcttaatttgtggaggaaatggtgtttgcaagtgtcgtgtgtgtgag
tgcaaccccaactacactggcagtgcatgtgactgttctttggatactagtacttgtgaa
gccagcaacggacagatctgcaatggccggggcatctgcgagtgtggtgtctgtaagtgt
acagatccgaagtttcaagggcaaacgtgtgagatgtgtcagacctgccttggtgtctgt
gctgagcataaagaatgtgttcagtgcagagccttcaataaaggagaaaagaaagacaca
tgcacacaggaatgttcctattttaacattaccaaggtagaaagtcgggacaaattaccc
cagccggtccaacctgatcctgtgtcccattgtaaggagaaggatgttgacgactgttgg
ttctattttacgtattcagtgaatgggaacaacgaggtcatggttcatgttgtggagaat
ccagagtgtcccactggtccagacatcattccaattgtagctggtgtggttgctggaatt
gttcttattggccttgcattactgctgatatggaagcttttaatgataattcatgacaga
agggagtttgctaaatttgaaaaggagaaaatgaatgccaaatgggacacgggtgaaaat
cctatttataagagtgccgtaacaactgtggtcaatccgaagtatgagggaaaatga

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