Homo sapiens (human): 2932
Help
Entry
2932 CDS
T01001
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase 3 beta
KO
K03083
glycogen synthase kinase 3 beta [EC:
2.7.11.26
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa01521
EGFR tyrosine kinase inhibitor resistance
hsa04012
ErbB signaling pathway
hsa04062
Chemokine signaling pathway
hsa04110
Cell cycle
hsa04150
mTOR signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04310
Wnt signaling pathway
hsa04340
Hedgehog signaling pathway
hsa04360
Axon guidance
hsa04390
Hippo signaling pathway
hsa04510
Focal adhesion
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04657
IL-17 signaling pathway
hsa04660
T cell receptor signaling pathway
hsa04662
B cell receptor signaling pathway
hsa04722
Neurotrophin signaling pathway
hsa04728
Dopaminergic synapse
hsa04910
Insulin signaling pathway
hsa04916
Melanogenesis
hsa04917
Prolactin signaling pathway
hsa04919
Thyroid hormone signaling pathway
hsa04931
Insulin resistance
hsa04932
Non-alcoholic fatty liver disease
hsa04934
Cushing syndrome
hsa04935
Growth hormone synthesis, secretion and action
hsa04936
Alcoholic liver disease
hsa05010
Alzheimer disease
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05131
Shigellosis
hsa05135
Yersinia infection
hsa05160
Hepatitis C
hsa05162
Measles
hsa05163
Human cytomegalovirus infection
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05215
Prostate cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06169
Measles virus (MV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06460
Alzheimer disease
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
nt06505
WNT signaling
nt06537
TCR/BCR signaling
nt06541
Cytoskeleton in neurons
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N00175
KSHV LANA to Wnt signaling pathway
N00242
Mutation-inactivated AXIN to Wnt signaling pathway
N00683
CD80/CD86-CD28-PI3K signaling pathway
N01017
Mutation-caused aberrant PSEN1 to anterograde axonal transport
N01202
Oligomeric conformation PrPc to anterograde axonal transport
N01403
Zn to anterograde axonal transport
N01832
NTN1-MAP1B axon guidance signaling
N01833
DRAXIN-MAP1B axon guidance signaling
N01858
EFNB1-MAPT axon guidance signaling
Drug target
Elraglusib:
D12304
Laduviglusib:
D12196
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
2932 (GSK3B)
04310 Wnt signaling pathway
2932 (GSK3B)
04340 Hedgehog signaling pathway
2932 (GSK3B)
04390 Hippo signaling pathway
2932 (GSK3B)
04151 PI3K-Akt signaling pathway
2932 (GSK3B)
04150 mTOR signaling pathway
2932 (GSK3B)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
2932 (GSK3B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
2932 (GSK3B)
04550 Signaling pathways regulating pluripotency of stem cells
2932 (GSK3B)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
2932 (GSK3B)
04657 IL-17 signaling pathway
2932 (GSK3B)
04662 B cell receptor signaling pathway
2932 (GSK3B)
04062 Chemokine signaling pathway
2932 (GSK3B)
09152 Endocrine system
04910 Insulin signaling pathway
2932 (GSK3B)
04917 Prolactin signaling pathway
2932 (GSK3B)
04935 Growth hormone synthesis, secretion and action
2932 (GSK3B)
04919 Thyroid hormone signaling pathway
2932 (GSK3B)
04916 Melanogenesis
2932 (GSK3B)
09156 Nervous system
04728 Dopaminergic synapse
2932 (GSK3B)
04722 Neurotrophin signaling pathway
2932 (GSK3B)
09158 Development and regeneration
04360 Axon guidance
2932 (GSK3B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
2932 (GSK3B)
09162 Cancer: specific types
05210 Colorectal cancer
2932 (GSK3B)
05225 Hepatocellular carcinoma
2932 (GSK3B)
05226 Gastric cancer
2932 (GSK3B)
05217 Basal cell carcinoma
2932 (GSK3B)
05215 Prostate cancer
2932 (GSK3B)
05213 Endometrial cancer
2932 (GSK3B)
05224 Breast cancer
2932 (GSK3B)
09172 Infectious disease: viral
05160 Hepatitis C
2932 (GSK3B)
05162 Measles
2932 (GSK3B)
05163 Human cytomegalovirus infection
2932 (GSK3B)
05167 Kaposi sarcoma-associated herpesvirus infection
2932 (GSK3B)
05165 Human papillomavirus infection
2932 (GSK3B)
09171 Infectious disease: bacterial
05131 Shigellosis
2932 (GSK3B)
05135 Yersinia infection
2932 (GSK3B)
09164 Neurodegenerative disease
05010 Alzheimer disease
2932 (GSK3B)
05020 Prion disease
2932 (GSK3B)
05022 Pathways of neurodegeneration - multiple diseases
2932 (GSK3B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
2932 (GSK3B)
05415 Diabetic cardiomyopathy
2932 (GSK3B)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
2932 (GSK3B)
04932 Non-alcoholic fatty liver disease
2932 (GSK3B)
04931 Insulin resistance
2932 (GSK3B)
04934 Cushing syndrome
2932 (GSK3B)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
2932 (GSK3B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
2932 (GSK3B)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
2932 (GSK3B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
2932 (GSK3B)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CMGC group
GSK family [OT]
2932 (GSK3B)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
2932 (GSK3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Kdo
APH
Choline_kinase
Motif
Other DBs
NCBI-GeneID:
2932
NCBI-ProteinID:
NP_001139628
OMIM:
605004
HGNC:
4617
Ensembl:
ENSG00000082701
Pharos:
P49841
(Tclin)
UniProt:
P49841
Q6FI27
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(119821321..120094447)
Genome browser
AA seq
420 aa
AA seq
DB search
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggacggcagcaaggtgacaacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatggatcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggtcgccatcaagaaagtattgcaggacaagagatttaagaatcgagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatttatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccgcagaacctcttgttggatcctgatactgctgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggat
agtggtgtggatcagttggtagaaataatcaaggtcctgggaactccaacaagggagcaa
atcagagaaatgaacccaaactacacagaatttaaattccctcaaattaaggcacatcct
tggactaaggtcttccgaccccgaactccaccggaggcaattgcactgtgtagccgtctg
ctggagtatacaccaactgcccgactaacaccactggaagcttgtgcacattcatttttt
gatgaattacgggacccaaatgtcaaactaccaaatgggcgagacacacctgcactcttc
aacttcaccactcaagaactgtcaagtaatccacctctggctaccatccttattcctcct
catgctcggattcaagcagctgcttcaacccccacaaatgccacagcagcgtcagatgct
aatactggagaccgtggacagaccaataatgctgcttctgcatcagcttccaactccacc
tga
Homo sapiens (human): 8312
Help
Entry
8312 CDS
T01001
Symbol
AXIN1, AXIN, CMDOH, PPP1R49
Name
(RefSeq) axin 1
KO
K02157
axin 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N00242
Mutation-inactivated AXIN to Wnt signaling pathway
Disease
H00048
Hepatocellular carcinoma
H00934
Caudal duplication anomaly
H01667
Medulloblastoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8312 (AXIN1)
04390 Hippo signaling pathway
8312 (AXIN1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
8312 (AXIN1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8312 (AXIN1)
09162 Cancer: specific types
05210 Colorectal cancer
8312 (AXIN1)
05225 Hepatocellular carcinoma
8312 (AXIN1)
05226 Gastric cancer
8312 (AXIN1)
05217 Basal cell carcinoma
8312 (AXIN1)
05213 Endometrial cancer
8312 (AXIN1)
05224 Breast cancer
8312 (AXIN1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
8312 (AXIN1)
09164 Neurodegenerative disease
05010 Alzheimer disease
8312 (AXIN1)
05022 Pathways of neurodegeneration - multiple diseases
8312 (AXIN1)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
8312 (AXIN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
8312 (AXIN1)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
8312 (AXIN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DIX
RGS
AXIN1_TNKS_BD
Axin_b-cat_bind
Motif
Other DBs
NCBI-GeneID:
8312
NCBI-ProteinID:
NP_003493
OMIM:
603816
HGNC:
903
Ensembl:
ENSG00000103126
Pharos:
O15169
(Tbio)
UniProt:
O15169
A0A0S2Z4R0
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:complement(287440..352723)
Genome browser
AA seq
862 aa
AA seq
DB search
MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC
DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
REDEAVLPVFEEKIIGKVEKVD
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgaatatccaagagcagggtttccccttggacctcggagcaagtttcaccgaagatgct
ccccgacccccagtgcctggtgaggagggagaactggtgtccacagacccgaggcccgcc
agctacagtttctgctccgggaaaggtgttggcattaaaggtgagacttcgacggccact
ccgaggcgctcggatctggacctggggtatgagcctgagggcagtgcctcccccacccca
ccatacttgaagtgggctgagtcactgcattccctgctggatgaccaagatgggataagc
ctgttcaggactttcctgaagcaggagggctgtgccgacttgctggacttctggtttgcc
tgcactggcttcaggaagctggagccctgtgactcgaacgaggagaagaggctgaagctg
gcgagagccatctaccgaaagtacattcttgataacaatggcatcgtgtcccggcagacc
aagccagccaccaagagcttcataaagggctgcatcatgaagcagctgatcgatcctgcc
atgtttgaccaggcccagaccgaaatccaggccactatggaggaaaacacctatccctcc
ttccttaagtctgatatttatttggaatatacgaggacaggctcggagagccccaaagtc
tgtagtgaccagagctctgggtcagggacagggaagggcatatctggatacctgccgacc
ttaaatgaagatgaggaatggaagtgtgaccaggacatggatgaggacgatggcagagac
gctgctccccccggaagactccctcagaagctgctcctggagacagctgccccgagggtc
tcctccagtagacggtacagcgaaggcagagagttcaggtatggatcctggcgggagcca
gtcaacccctattatgtcaatgccggctatgccctggccccagccaccagtgccaacgac
agcgagcagcagagcctgtccagcgatgcagacaccctgtccctcacggacagcagcgtg
gatgggatccccccatacaggatccgtaagcagcaccgcagggagatgcaggagagcgtg
caggtcaatgggcgggtgcccctacctcacattccccgcacgtaccgggtgccgaaggag
gtccgcgtggagcctcagaagttcgcggaggagctcatccaccgcctggaggctgtgcag
cgcacgcgggaggccgaggagaagctggaggagcggctgaagcgcgtgcgcatggaggag
gaaggtgaggacggcgatccatcgtcagggcccccagggccgtgtcacaagctgcctccc
gcccccgcttggcaccacttcccgccccgctgtgtggacatgggctgtgccgggctccgg
gatgcacacgaggagaaccctgagagcatcctggacgagcacgtacagcgtgtgctgagg
acacctggccgccagtcgcctgggcctggccatcgctccccggacagtgggcacgtggcc
aagatgccagtggcactggggggtgccgcctcggggcacgggaagcacgtacccaagtca
ggggcgaagctggacgcggccggcctgcaccaccaccgacacgtccaccaccacgtccac
cacagcacagcccggcccaaggagcaggtggaggccgaggccacccgcagggcccagagc
agcttcgcctggggcctggaaccacacagccatggggcaaggtcccgaggctactcagag
agtgttggcgctgcccccaacgccagtgatggcctcgcccacagtgggaaggtgggcgtg
gcgtgcaaaagaaatgccaagaaggctgagtcggggaagagcgccagcaccgaggtgcca
ggtgcctcggaggatgcggagaagaaccagaaaatcatgcagtggatcattgagggggaa
aaggagatcagcaggcaccgcaggaccggccacgggtcttcggggacgaggaagccacag
ccccatgagaactccagacccttgtcccttgagcacccctgggccggccctcagctccgg
acctccgtgcagccctcccacctcttcatccaagaccccaccatgccaccccacccagct
cccaaccccctaacccagctggaggaggcgcgccgacgtctggaggaggaagaaaagaga
gccagccgagcaccctccaagcagaggtatgtgcaggaggttatgcggcggggacgcgcc
tgcgtcaggccagcgtgcgcgccggtgctgcacgtggtaccagccgtgtcggacatggag
ctctccgagacagagacaagatcgcagaggaaggtgggcggcgggagtgcccagccgtgt
gacagcatcgttgtggcgtactacttctgcggggaacccatcccctaccgcaccctggtg
aggggccgcgctgtcaccctgggccagttcaaggagctgctgaccaaaaagggcagctac
agatactacttcaagaaagtgagcgacgagtttgactgtggggtggtgtttgaggaggtt
cgagaggacgaggccgtcctgcccgtctttgaggagaagatcatcggcaaagtggagaag
gtggactga
Homo sapiens (human): 8313
Help
Entry
8313 CDS
T01001
Symbol
AXIN2, AXIL, ODCRCS
Name
(RefSeq) axin 2
KO
K04385
axin 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
Disease
H00020
Colorectal cancer
H00857
Oligodontia-colorectal cancer syndrome
H01667
Medulloblastoma
H02302
Hepatoblastoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8313 (AXIN2)
04390 Hippo signaling pathway
8313 (AXIN2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
8313 (AXIN2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8313 (AXIN2)
09162 Cancer: specific types
05210 Colorectal cancer
8313 (AXIN2)
05225 Hepatocellular carcinoma
8313 (AXIN2)
05226 Gastric cancer
8313 (AXIN2)
05217 Basal cell carcinoma
8313 (AXIN2)
05213 Endometrial cancer
8313 (AXIN2)
05224 Breast cancer
8313 (AXIN2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
8313 (AXIN2)
09164 Neurodegenerative disease
05010 Alzheimer disease
8313 (AXIN2)
05022 Pathways of neurodegeneration - multiple diseases
8313 (AXIN2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
8313 (AXIN2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
8313 (AXIN2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
8313 (AXIN2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS
DIX
AXIN1_TNKS_BD
Axin_b-cat_bind
DUF4827
DUF3005
Motif
Other DBs
NCBI-GeneID:
8313
NCBI-ProteinID:
NP_004646
OMIM:
604025
HGNC:
904
Ensembl:
ENSG00000168646
Pharos:
Q9Y2T1
(Tchem)
UniProt:
Q9Y2T1
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(65528563..65561648)
Genome browser
AA seq
843 aa
AA seq
DB search
MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGETPPCQPGVGKGQVTKPMPVSSNTRRNED
GLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQM
NLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQS
VMEENAYQMFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVVCGYLPTLNEEEEWTCADFK
CKLSPTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGSGYVFAPATSANDS
EISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPK
EMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGSELTLNSREGAPTQ
HPLSLLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHHHHSQYHSL
LPPGGKLPPAAASPGACPLLGGKGFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVH
CFCPGGSEYYCYSKCKSHSKAPETMPSEQFGGSRGSTLPKRNGKGTEPGLALPAREGGAP
GGAGALQLPREEGDRSQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRH
HLWGGNSGHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQ
QRDRNHSATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRM
LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVE
RID
NT seq
2532 nt
NT seq
+upstream
nt +downstream
nt
atgagtagcgctatgttggtgacttgcctcccggaccccagcagcagcttccgtgaggat
gccccgcggcccccagtgccaggggaagaaggggagaccccaccgtgtcagccaggggtg
ggcaagggccaggtcaccaaacccatgcctgtctcttccaacaccaggcggaacgaagat
gggttgggggagccggaggggcgggcatctccggattcccctctgacccggtggaccaag
tccttacactccttattgggcgatcaagacggtgcttacctgttccgaactttcctggag
agggagaaatgcgtggataccttagacttctggtttgcctgcaatggattcaggcagatg
aacctgaaggataccaaaactttacgagtagccaaagcgatctacaaaaggtacattgag
aacaacagcattgtctccaagcagctgaagcctgccaccaagacctacataagagatggc
atcaagaagcagcagattgattccatcatgtttgaccaggcgcagaccgagatccagtcg
gtgatggaggaaaatgcctaccagatgtttttgacttctgatatatacctcgaatatgtg
aggagtgggggagaaaacacagcttacatgagtaatgggggactcgggagcctaaaggtc
gtgtgtggctatctccccaccttgaatgaagaagaggagtggacttgtgccgacttcaag
tgcaaactttcgccaaccgtggttggcttgtccagcaaaactctgagggccacggcgagt
gtgaggtccacggaaactgttgacagtggatacaggtccttcaagaggagcgatcctgtt
aatccttatcacataggttctggctatgtctttgcaccagccaccagcgccaacgacagt
gagatatccagtgatgcgctgacggatgattccatgtccatgacggacagcagtgtagat
ggaattcctccttatcgtgtgggcagtaagaaacagctccagagagaaatgcatcgcagt
gtgaaggccaatggccaagtgtctctacctcatttcccgagaacccaccgcctgcccaag
gagatgacccccgtggaacccgccacctttgcagctgagctgatctcgaggctggaaaag
ctgaagctggagttggagagccgccacagcctggaggagcgcctgcagcagatccgagag
gatgaagagagagagggctccgagctcacactcaattcgcgggagggggcgcccacgcag
caccccctctccctactgccctccggcagctacgaggaagacccgcagacgatactggac
gatcacctgtccagggtcctcaagacccctggctgccagtctccaggcgtaggccgctat
agcccccgctcccgctccccggaccaccaccaccaccaccattcgcagtaccactccctg
ctcccgcccggtggcaagctgcctcccgcggccgcctcgccgggcgcctgccccctcctc
gggggcaaaggctttgtgaccaagcagacgacgaagcatgtccaccaccactacatccac
caccatgccgtccccaagaccaaggaggagatcgaggcggaggccacgcagcgggtgcac
tgcttctgccctgggggcagcgagtattactgctactcgaaatgcaaaagccactccaag
gctccggaaaccatgcccagcgagcagtttggcggcagcagaggcagtaccttgcccaaa
cgcaatgggaaaggcacggagccgggcctggccctgcccgccagggaaggaggggccccc
ggcggagctggggccctgcagcttccccgggaggaaggagacaggtcgcaggatgtctgg
cagtggatgctggagagtgagcggcagagcaagcccaagccccatagtgcccaaagcaca
aaaaaggcctaccccttggagtctgcccgctcgtctccaggcgaacgagccagccggcac
catctgtgggggggcaacagcgggcacccccgcaccaccccccgtgcccacctgttcacc
caggaccctgcgatgcctcccctgaccccacccaacacgctggctcagctggaggaggcc
tgtcgcaggctagctgaggtgtcgaagcccccaaagcagcggtgctgtgtggccagtcag
cagagggacaggaatcattcggccactgttcagacgggagccacacccttctccaatcca
agcctggctccagaagatcacaaagagccaaagaaactggcaggtgtccacgcgctccag
gccagtgagttggttgtcacttactttttctgtggggaagaaattccataccggaggatg
ctgaaggctcagagcttgaccctgggccactttaaagagcagctcagcaaaaagggaaat
tataggtattacttcaaaaaagcaagcgatgagtttgcctgtggagcggtgtttgaggag
atctgggaggatgagacggtgctcccgatgtatgaaggccggattctgggcaaagtggag
cggatcgattga
DBGET
integrated database retrieval system