KEGG   Homo sapiens (human): 5154
Entry
5154              CDS       T01001                                 
Symbol
PDGFA, PDGF-A, PDGF1
Name
(RefSeq) platelet derived growth factor subunit A
  KO
K04359  platelet-derived growth factor subunit A
Organism
hsa  Homo sapiens (human)
Pathway
hsa01521  EGFR tyrosine kinase inhibitor resistance
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04072  Phospholipase D signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04540  Gap junction
hsa04630  JAK-STAT signaling pathway
hsa04810  Regulation of actin cytoskeleton
hsa05200  Pathways in cancer
hsa05202  Transcriptional misregulation in cancer
hsa05206  MicroRNAs in cancer
hsa05214  Glioma
hsa05215  Prostate cancer
hsa05218  Melanoma
hsa05231  Choline metabolism in cancer
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06110  MAPK signaling (viruses and bacteria)
nt06114  PI3K signaling (viruses)
nt06166  Human papillomavirus (HPV)
nt06167  Human cytomegalovirus (HCMV)
nt06210  ERK signaling
nt06214  PI3K signaling
nt06220  Calcium signaling
nt06240  Transcription
nt06273  Glioma
  Element
N00015  PDGF-PDGFR-RAS-ERK signaling pathway
N00016  PDGF-overexpression to RAS-ERK signaling pathway
N00028  PDGF-PDGFR-PLCG-CAMK signaling pathway
N00039  PDGF-PDGFR-PI3K signaling pathway
N00137  EWSR1-WT1 fusion to transcriptional activation
Disease
H00015  Malignant pleural mesothelioma
H00042  Glioma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5154 (PDGFA)
   04014 Ras signaling pathway
    5154 (PDGFA)
   04015 Rap1 signaling pathway
    5154 (PDGFA)
   04630 JAK-STAT signaling pathway
    5154 (PDGFA)
   04020 Calcium signaling pathway
    5154 (PDGFA)
   04072 Phospholipase D signaling pathway
    5154 (PDGFA)
   04151 PI3K-Akt signaling pathway
    5154 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5154 (PDGFA)
   04540 Gap junction
    5154 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5154 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    5154 (PDGFA)
   05202 Transcriptional misregulation in cancer
    5154 (PDGFA)
   05206 MicroRNAs in cancer
    5154 (PDGFA)
   05231 Choline metabolism in cancer
    5154 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    5154 (PDGFA)
   05218 Melanoma
    5154 (PDGFA)
   05215 Prostate cancer
    5154 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    5154 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    5154 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    5154 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    5154 (PDGFA)
Cytokines and growth factors [BR:hsa04052]
 Growth factors
  Growth factors (RTK binding)
   5154 (PDGFA)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   5154 (PDGFA)
SSDB
Motif
Pfam: PDGF_N PDGF SyrA
Other DBs
NCBI-GeneID: 5154
NCBI-ProteinID: NP_002598
OMIM: 173430
HGNC: 8799
Ensembl: ENSG00000197461
Vega: OTTHUMG00000151412
Pharos: P04085(Tchem)
UniProt: P04085
Structure
LinkDB
Position
7:complement(497258..520700)
AA seq 211 aa
MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
NT seq 636 nt   +upstreamnt  +downstreamnt
atgaggaccttggcttgcctgctgctcctcggctgcggatacctcgcccatgttctggcc
gaggaagccgagatcccccgcgaggtgatcgagaggctggcccgcagtcagatccacagc
atccgggacctccagcgactcctggagatagactccgtagggagtgaggattctttggac
accagcctgagagctcacggggtccatgccactaagcatgtgcccgagaagcggcccctg
cccattcggaggaagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacg
gtcatttacgagattcctcggagtcaggtcgaccccacgtccgccaacttcctgatctgg
cccccgtgcgtggaggtgaaacgctgcaccggctgctgcaacacgagcagtgtcaagtgc
cagccctcccgcgtccaccaccgcagcgtcaaggtggccaaggtggaatacgtcaggaag
aagccaaaattaaaagaagtccaggtgaggttagaggagcatttggagtgcgcctgcgcg
accacaagcctgaatccggattatcgggaagaggacacgggaaggcctagggagtcaggt
aaaaaacggaaaagaaaaaggttaaaacccacctaa

KEGG   Homo sapiens (human): 3560
Entry
3560              CDS       T01001                                 
Symbol
IL2RB, CD122, IL15RB, IMD63, P70-75
Name
(RefSeq) interleukin 2 receptor subunit beta
  KO
K05069  interleukin 2 receptor beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04061  Viral protein interaction with cytokine and cytokine receptor
hsa04144  Endocytosis
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa05162  Measles
hsa05166  Human T-cell leukemia virus 1 infection
hsa05200  Pathways in cancer
hsa05202  Transcriptional misregulation in cancer
Network
nt06119  JAK-STAT signaling (viruses)
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06162  Hepatitis B virus (HBV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06219  JAK-STAT signaling
nt06240  Transcription
nt06263  Hepatocellular carcinoma
nt06266  Non-small cell lung cancer
nt06276  Chronic myeloid leukemia
  Element
N00053  Cytokine-Jak-STAT signaling pathway
N00137  EWSR1-WT1 fusion to transcriptional activation
N00491  HTLV-1 p12 to Jak-STAT signaling pathway
N01268  IL2 to IL2R signaling
Disease
H02525  Disorders of innate immunity
Drug target
Aldesleukin: D00748<US>
Bempegaldesleukin: D11669
Celmoleukin: D02743
Rezpegaldesleukin: D12328
Teceleukin: D02749<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    3560 (IL2RB)
   04151 PI3K-Akt signaling pathway
    3560 (IL2RB)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3560 (IL2RB)
   04061 Viral protein interaction with cytokine and cytokine receptor
    3560 (IL2RB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3560 (IL2RB)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    3560 (IL2RB)
   04659 Th17 cell differentiation
    3560 (IL2RB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3560 (IL2RB)
   05202 Transcriptional misregulation in cancer
    3560 (IL2RB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    3560 (IL2RB)
   05162 Measles
    3560 (IL2RB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    3560 (IL2RB)
   04090 CD molecules [BR:hsa04090]
    3560 (IL2RB)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL2 receptor family
   3560 (IL2RB)
CD molecules [BR:hsa04090]
 Proteins
  3560 (IL2RB)
SSDB
Motif
Pfam: IL2RB_N1 Pur_ac_phosph_N IL6Ra-bind
Other DBs
NCBI-GeneID: 3560
NCBI-ProteinID: NP_000869
OMIM: 146710
HGNC: 6009
Ensembl: ENSG00000100385
Vega: OTTHUMG00000150534
Pharos: P14784(Tclin)
UniProt: P14784
Structure
LinkDB
Position
22:complement(37125838..37175118)
AA seq 551 aa
MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQ
VHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMA
IQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEE
APLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDT
IPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDV
QKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFT
NQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCT
FPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVP
DLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQ
ELQGQDPTHLV
NT seq 1656 nt   +upstreamnt  +downstreamnt
atggcggcccctgctctgtcctggcgtctgcccctcctcatcctcctcctgcccctggct
acctcttgggcatctgcagcggtgaatggcacttcccagttcacatgcttctacaactcg
agagccaacatctcctgtgtctggagccaagatggggctctgcaggacacttcctgccaa
gtccatgcctggccggacagacggcggtggaaccaaacctgtgagctgctccccgtgagt
caagcatcctgggcctgcaacctgatcctcggagccccagattctcagaaactgaccaca
gttgacatcgtcaccctgagggtgctgtgccgtgagggggtgcgatggagggtgatggcc
atccaggacttcaagccctttgagaaccttcgcctgatggcccccatctccctccaagtt
gtccacgtggagacccacagatgcaacataagctgggaaatctcccaagcctcccactac
tttgaaagacacctggagttcgaggcccggacgctgtccccaggccacacctgggaggag
gcccccctgctgactctcaagcagaagcaggaatggatctgcctggagacgctcacccca
gacacccagtatgagtttcaggtgcgggtcaagcctctgcaaggcgagttcacgacctgg
agcccctggagccagcccctggccttcaggacaaagcctgcagcccttgggaaggacacc
attccgtggctcggccacctcctcgtgggcctcagcggggcttttggcttcatcatctta
gtgtacttgctgatcaactgcaggaacaccgggccatggctgaagaaggtcctgaagtgt
aacaccccagacccctcgaagttcttttcccagctgagctcagagcatggaggagacgtc
cagaagtggctctcttcgcccttcccctcatcgtccttcagccctggcggcctggcacct
gagatctcgccactagaagtgctggagagggacaaggtgacgcagctgctcctgcagcag
gacaaggtgcctgagcccgcatccttaagcagcaaccactcgctgaccagctgcttcacc
aaccagggttacttcttcttccacctcccggatgccttggagatagaggcctgccaggtg
tactttacttacgacccctactcagaggaagaccctgatgagggtgtggccggggcaccc
acagggtcttccccccaacccctgcagcctctgtcaggggaggacgacgcctactgcacc
ttcccctccagggatgacctgctgctcttctcccccagtctcctcggtggccccagcccc
ccaagcactgcccctgggggcagtggggccggtgaagagaggatgcccccttctttgcaa
gaaagagtccccagagactgggacccccagcccctggggcctcccaccccaggagtccca
gacctggtggattttcagccaccccctgagctggtgctgcgagaggctggggaggaggtc
cctgacgctggccccagggagggagtcagtttcccctggtccaggcctcctgggcagggg
gagttcagggcccttaatgctcgcctgcccctgaacactgatgcctacttgtccctccaa
gaactccagggtcaggacccaactcacttggtgtag

KEGG   Homo sapiens (human): 8938
Entry
8938              CDS       T01001                                 
Symbol
BAIAP3, BAP3
Name
(RefSeq) BAI1 associated protein 3
  KO
K15621  BAI1-associated protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription
  Element
N00137  EWSR1-WT1 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    8938 (BAIAP3)
SSDB
Motif
Pfam: C2 MUN
Other DBs
NCBI-GeneID: 8938
NCBI-ProteinID: NP_003924
OMIM: 604009
HGNC: 948
Ensembl: ENSG00000007516
Vega: OTTHUMG00000047833
Pharos: O94812(Tbio)
UniProt: O94812
LinkDB
Position
16:1333645..1349439
AA seq 1187 aa
MRPRGAAFAAGPPGDLHLGTAIGFAGAIWRSRSPAMSTLLDIKSSVLRQVQVCPSFRRRT
EQDPGSASADPQEPATGAWKPGDGVEFFAHMRLMLKKGEGRQGLPCLEVPLRSGSPAPPE
PVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLEEH
TEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQ
RFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDV
SLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAG
VDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRLEHSA
EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYLLGLL
EDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLELLLKC
LGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPGLVVL
ADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLEVAS
GLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQGAVD
MDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEATLFY
TELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPEGATGPEGVLPRP
LLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQNDEAVAPLMKYLDE
KLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFHFTLEALVSFFHA
EGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVRCHY
EAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYD
ELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARPQVGGGARAG
QPVTLHLCRPRAQVRSALRRLEGRTSKEAQEFVKKLKELEKCMEADP
NT seq 3564 nt   +upstreamnt  +downstreamnt
atgagaccccggggagcagcgtttgcagcgggcccgccaggtgacctgcacctgggcacc
gccatcggcttcgcaggggccatctggaggagtcggtcacccgccatgtcgaccttgctg
gacattaagagcagcgtgctcaggcaggtgcaggtgtgcccgtccttccgccgcaggact
gagcaggacccagggagtgccagcgccgacccgcaggagcctgccacgggggcctggaaa
cccggggatggcgtggagttctttgcccacatgcgcctcatgctgaagaagggggaaggc
agacagggcttgccgtgcctcgaggtccccctgcgcagtggctcgccagcacccccggag
cctgtggatcccagcctcggcctgagagccctggccccagaggaggtggagatgctctac
gaggaggccctgtacacggtgctttaccgcgcgggtaccatgggccctgaccaggtggac
gacgaggaggccctgctcagctatctccagcaggtgtttggcaccagccttgaggagcac
actgaggccatcgagcgagtgaggaaggccaaggcccccacgtatgccctgaaagtctct
gtcatgcgtgccaagaaccttctggccaaggaccccaacggcttcagcgacccatactgc
atgctgggcatcctgcctgcctcggacgccacgcgggagccccgtgcacagaaggagcag
cgcttcggcttccgcaagggcagcaagcgcggtggacccctgcctgccaagtgcatccag
gtcaccgaggtgaagagcagcaccctgaaccccgtctggaaggagcacttcctcttcgag
attgaggatgtgagcacggaccagctgcacctggacatctgggatcatgacgacgatgta
tccctggtagaagcgtgcaggaagctgaatgaagtcatcggcctgaagggcatgggcagg
tacttcaaacagatcgtcaagtcagcccgcgcaaacgggacagcaggacccaccgaggac
cacaccgatgacttcctggggtgcctcaacatacctgtccgggaggtgcctgtggctggc
gtcgaccgctggttcaagctggagccacgctccagtgcctcgcgtgtgcagggacactgc
cacctggttctcaagctgatcactacgcagagggatacggccatgagccagcgcgggcga
tccggcttcctgtcccacctgctgctgctcagccatctgctgcggttggagcactcagca
gaggagcccaactccagcagctggcgaggagagctcagcacaccagccgccaccatcctc
tgcctgcacggagcccagagcaacctgtcacccttgcagctggccgtgctgcactggcag
gtcagcagccgccaccatcaaacctgcacgctggactacagctacctgctggggctgctg
gaggacatgcaggcacactgggaagaggctccttcactgccccaggagcaggaggagagc
ctggctgatagcctttccgccttctctgagttcgggctgcagctgctgcgccagctccga
gactacttccctgccaccaacagcaccgctgtccaccgcctggagctgctgctgaagtgt
ctgggcaagctgcagctcttccaaccctcctttgagatctgccccttcgagtcggagctg
aacatggacattgctgcggccctgaagagaggcaaccgtgagtggtacgacaggatcctg
aatgacaagagtccccgagagcagccaggaccacagcgcctgcctgggctggttgtgctg
gctgacgccgtctatgatgaccttcagttctgctacagtgtgtacgccagcctcttccac
agcatcctcaatgtggacgtcttcaccctgaccttccggcagctggagcgtctggtggct
gaggaggcgtgggtgctgacggaggagctgagccccaagatgaccctggaggtggcctcg
gggctctttgagctctacctgaccctggctgacctccagcgcttctgggatagcatccct
ggccgggacagccgctctctggccctggctggcatccacgcccccttcctgcctgctgtg
aagctctggttccaagtgctgagggaccaggccaagtggaggcttcagggagccgtggac
atggacacgctggagcccgtggacgcctcctccaggcacagcagctccgcagccactgct
ggtctctgcctcagccacatccaggagttgtgggtgcgcctggcgtggcctgaccctgcc
caggctcaggggctgggcacccagcttggccaggacgtgtgtgaggccaccctcttctat
acggagctgcttcggaagaaggtggacactcagccaggggcggccggtgaagcagtgagc
gaggcgctctgcgtggtcctcaacaatgtggagctcgtgcgcaaggctgctgggcaggcc
ttgaagggcctggcatggccagagggggccacggggcccgagggggtgctcccccgccct
ctgctcagctgcacacaggccctggacgatgatctgcaacgggaggcccacacggtgaca
gcgcacctgacctctaagatggtgggcgacatccgcaagtatgtacagcacatcagtctc
tcgcctgactccatccagaacgatgaggccgtggccccgctcatgaagtacctggatgag
aagctggccctgctgaacgcctcgctggtgaaggggaacctgagcagggtgctggaggcc
ctgtgggagctactcctccaggccattctgcaggcgctgggtgcaaaccgtgacgtctct
gctgatttctacagccgcttccatttcacgctggaggccctggtcagttttttccacgca
gagggtcagggtttgcccctggagagcctgagggatggaagctacaagaggctgaaggag
gagctgcggctgcacaaatgttccacccgcgagtgcatcgagcagttctacctggacaag
ctcaaacagaggaccctggagcagaaccggtttggacgcctgagcgtccgttgccattac
gaggcggctgagcagcggctggccgtggaggtgctgcacgccgcggacctgctccccctg
gacgccaacggcttaagtgacccctttgtgatcgtggagctgggcccaccgcatctcttt
ccactggtccgcagccagaggacccaggtgaagacccggacgctgcaccctgtatacgac
gaactcttctacttttccgtgcctgccgaggcgtgccgccgccgcgcggcctgtgtgttg
ttcaccgtcatggaccacgactggctgtccaccaacgacttcgctggggaggcggccctc
ggcctaggtggcgtcactggtgtcgcccggccccaggtgggcgggggtgcaagggctggg
cagcctgtcaccctgcacctgtgccggcccagagcccaggtgagatctgcgctgaggagg
ctggaaggccgcaccagcaaggaggcgcaggagttcgtgaagaaactcaaggagctggag
aagtgcatggaggcggacccctga

KEGG   Homo sapiens (human): 7102
Entry
7102              CDS       T01001                                 
Symbol
TSPAN7, A15, CCG-B7, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b, XLID58
Name
(RefSeq) tetraspanin 7
  KO
K06571  tetraspanin-7
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription
  Element
N00137  EWSR1-WT1 fusion to transcriptional activation
Disease
H00480  X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    7102 (TSPAN7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7102 (TSPAN7)
   04090 CD molecules [BR:hsa04090]
    7102 (TSPAN7)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   7102 (TSPAN7)
CD molecules [BR:hsa04090]
 Proteins
  7102 (TSPAN7)
SSDB
Motif
Pfam: Tetraspanin Endonuclease_1
Other DBs
NCBI-GeneID: 7102
NCBI-ProteinID: NP_004606
OMIM: 300096
HGNC: 11854
Ensembl: ENSG00000156298
Vega: OTTHUMG00000024090
Pharos: P41732(Tbio)
UniProt: P41732
LinkDB
Position
X:38561542..38688918
AA seq 249 aa
MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPY
VLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTF
LRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD
CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF
ITANQYEMV
NT seq 750 nt   +upstreamnt  +downstreamnt
atggcatcgaggagaatggagaccaaacctgtgataacctgtctcaaaaccctcctcatc
atctactccttcgtcttctggatcactggggtgatcctgctggctgttggagtctggggc
aaacttactctgggcacctatatctcccttattgccgagaactccacaaatgctccctat
gtgctcatcggaactggcaccactattgttgtctttggcctgtttggatgctttgctaca
tgtcgtggtagcccatggatgctgaaactgtatgccatgtttctgtccctggtgttcctg
gctgagctcgtagctggcatttcagggtttgtgtttcgtcatgagatcaaggacaccttc
ctgaggacttacacggacgctatgcagacttacaatggcaatgatgagaggagccgggca
gtggaccatgtgcagcgcagcctgagctgctgtggtgtgcagaactacaccaactggagc
accagcccctacttcctggagcatggcatcccccccagctgctgcatgaacgaaactgat
tgtaatccccaggatctacacaatctgactgtggccgccaccaaagttaaccagaagggt
tgttatgatctggtaactagtttcatggagactaacatgggaatcatcgctggagtggcg
tttggaatcgcattctcccagttaattggcatgctgctggcctgctgtctgtcccggttc
atcacggccaatcagtatgagatggtgtaa

KEGG   Homo sapiens (human): 4291
Entry
4291              CDS       T01001                                 
Symbol
MLF1
Name
(RefSeq) myeloid leukemia factor 1
  KO
K15622  myeloid leukemia factor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription
  Element
N00137  EWSR1-WT1 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    4291 (MLF1)
SSDB
Motif
Pfam: Mlf1IP
Other DBs
NCBI-GeneID: 4291
NCBI-ProteinID: NP_071888
OMIM: 601402
HGNC: 7125
Ensembl: ENSG00000178053
Vega: OTTHUMG00000158775
Pharos: P58340(Tbio)
UniProt: P58340 A0A0S2Z4U8 Q5HYH4 B2RD48
Structure
LinkDB
Position
3:158571194..158606456
AA seq 268 aa
MFRMLNSSFEDDPFFSESILAHRENMRQMIRSFSEPFGRDLLSISDGRGRAHNRRGHNDG
EDSLTHTDVSSFQTMDQMVSNMRNYMQKLERNFGQLSVDPNGHSFCSSSVMTYSKIGDEP
PKVFQASTQTRRAPGGIKETRKAMRDSDSGLEKMAIGHHIHDRAHVIKKSKNKKTGDEEV
NQEFINMNESDAHAFDEEWQSEVLKYKPGRHNLGNTRMRSVGHENPGSRELKRREKPQQS
PAIEHGRRSNVLGDKLHIKGSSVKSNKK
NT seq 807 nt   +upstreamnt  +downstreamnt
atgttcaggatgctgaacagcagttttgaggatgaccccttcttctctgagtccattctt
gcacaccgagaaaatatgcgacagatgataagaagtttttctgaaccctttggaagagac
ttgctcagtatctctgatggtagagggagagctcataatcgtagaggacataatgatggt
gaagattctttgactcatacagatgtcagctctttccagacaatggaccaaatggtgtca
aatatgagaaactatatgcagaaattagaaagaaacttcggtcaactttcagtggatcca
aatggacattcattttgttcttcctcagttatgacttattccaaaataggagatgaaccg
ccaaaggtttttcaggcctcaactcaaactcgtcgagctccaggaggaataaaggaaacc
aggaaagcaatgagagattctgacagtggactagaaaaaatggctattggtcatcatatc
catgaccgagctcatgtcattaaaaagtcaaagaacaagaagactggagatgaagaggtc
aaccaggagttcatcaatatgaatgaaagtgatgctcatgcttttgatgaggagtggcaa
agtgaggttttgaagtacaaaccaggacgacacaatctaggaaacactagaatgagaagt
gttggccatgagaatcctggctcccgagaacttaaaagaagggagaaacctcaacaaagt
ccagccattgaacatggaaggagatcaaatgttttgggggacaaactccacatcaaaggc
tcatctgtgaaaagcaacaaaaaataa

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