Homo sapiens (human): 578
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Entry
578 CDS
T01001
Symbol
BAK1, BAK, BAK-LIKE, BCL2L7, CDN1
Name
(RefSeq) BCL2 antagonist/killer 1
KO
K14021
Bcl-2 homologous antagonist/killer
Organism
hsa
Homo sapiens (human)
Pathway
hsa01524
Platinum drug resistance
hsa04141
Protein processing in endoplasmic reticulum
hsa04210
Apoptosis
hsa04215
Apoptosis - multiple species
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05130
Pathogenic Escherichia coli infection
hsa05132
Salmonella infection
hsa05160
Hepatitis C
hsa05162
Measles
hsa05163
Human cytomegalovirus infection
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05203
Viral carcinogenesis
hsa05206
MicroRNAs in cancer
hsa05210
Colorectal cancer
hsa05212
Pancreatic cancer
hsa05213
Endometrial cancer
hsa05214
Glioma
hsa05216
Thyroid cancer
hsa05217
Basal cell carcinoma
hsa05218
Melanoma
hsa05220
Chronic myeloid leukemia
hsa05222
Small cell lung cancer
hsa05223
Non-small cell lung cancer
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06170
Influenza A virus (IAV)
nt06231
Apoptosis (cancer)
nt06240
Transcription (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06262
Pancreatic cancer
nt06263
Hepatocellular carcinoma
nt06265
Bladder cancer
nt06266
Non-small cell lung cancer
nt06267
Small cell lung cancer
nt06268
Melanoma
nt06269
Basal cell carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06273
Glioma
nt06274
Thyroid cancer
nt06276
Chronic myeloid leukemia
nt06460
Alzheimer disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
nt06524
Apoptosis
Element
N00098
Intrinsic apoptotic pathway
N00115
Mutation-inactivated TP53 to transcription
N00146
Crosstalk between extrinsic and intrinsic apoptotic pathways
N00164
KSHV vBCL2 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00223
EBV EBNA1 to p53-mediated transcription
N00263
EBV EBNA3C to p53-mediated transcription
N00383
HPV E6 to intrinsic apoptotic pathway
N00449
HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
N00476
EBV BHRF1 to intrinsic apoptotic pathway
N00478
EBV BARF1 to intrinsic apoptotic pathway
N00481
EBV BZLF1 to p53-mediated transcription
N01005
Mutation-caused aberrant Abeta to crosstalk between extrinsic and intrinsic apoptotic pathways
N01135
Mutation-caused aberrant SOD1 to intrinsic apoptotic pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
578 (BAK1)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
578 (BAK1)
04215 Apoptosis - multiple species
578 (BAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
578 (BAK1)
05202 Transcriptional misregulation in cancer
578 (BAK1)
05206 MicroRNAs in cancer
578 (BAK1)
05203 Viral carcinogenesis
578 (BAK1)
09162 Cancer: specific types
05210 Colorectal cancer
578 (BAK1)
05212 Pancreatic cancer
578 (BAK1)
05225 Hepatocellular carcinoma
578 (BAK1)
05226 Gastric cancer
578 (BAK1)
05214 Glioma
578 (BAK1)
05216 Thyroid cancer
578 (BAK1)
05220 Chronic myeloid leukemia
578 (BAK1)
05217 Basal cell carcinoma
578 (BAK1)
05218 Melanoma
578 (BAK1)
05213 Endometrial cancer
578 (BAK1)
05224 Breast cancer
578 (BAK1)
05222 Small cell lung cancer
578 (BAK1)
05223 Non-small cell lung cancer
578 (BAK1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
578 (BAK1)
05160 Hepatitis C
578 (BAK1)
05164 Influenza A
578 (BAK1)
05162 Measles
578 (BAK1)
05168 Herpes simplex virus 1 infection
578 (BAK1)
05163 Human cytomegalovirus infection
578 (BAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
578 (BAK1)
05169 Epstein-Barr virus infection
578 (BAK1)
05165 Human papillomavirus infection
578 (BAK1)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
578 (BAK1)
05132 Salmonella infection
578 (BAK1)
09164 Neurodegenerative disease
05022 Pathways of neurodegeneration - multiple diseases
578 (BAK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
578 (BAK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
hsa03029
]
578 (BAK1)
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
578 (BAK1)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Mitochondrial dynamics
Fission and Fusion factors
578 (BAK1)
Transporters [BR:
hsa02000
]
Other transporters
Pores ion channels [TC:
1
]
578 (BAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Bcl-2
Bcl-2_3
DUF5700
Motif
Other DBs
NCBI-GeneID:
578
NCBI-ProteinID:
NP_001179
OMIM:
600516
HGNC:
949
Ensembl:
ENSG00000030110
UniProt:
Q16611
A0A0S2Z391
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:complement(33572552..33580276)
Genome browser
AA seq
211 aa
AA seq
DB search
MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEM
VTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFE
SGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAA
LNLGNGPILNVLVVLGVVLLGQFVVRRFFKS
NT seq
636 nt
NT seq
+upstream
nt +downstream
nt
atggcttcggggcaaggcccaggtcctcccaggcaggagtgcggagagcctgccctgccc
tctgcttctgaggagcaggtagcccaggacacagaggaggttttccgcagctacgttttt
taccgccatcagcaggaacaggaggctgaaggggtggctgcccctgccgacccagagatg
gtcaccttacctctgcaacctagcagcaccatggggcaggtgggacggcagctcgccatc
atcggggacgacatcaaccgacgctatgactcagagttccagaccatgttgcagcacctg
cagcccacggcagagaatgcctatgagtacttcaccaagattgccaccagcctgtttgag
agtggcatcaattggggccgtgtggtggctcttctgggcttcggctaccgtctggcccta
cacgtctaccagcatggcctgactggcttcctaggccaggtgacccgcttcgtggtcgac
ttcatgctgcatcactgcattgcccggtggattgcacagaggggtggctgggtggcagcc
ctgaacttgggcaatggtcccatcctgaacgtgctggtggttctgggtgtggttctgttg
ggccagtttgtggtacgaagattcttcaaatcatga
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integrated database retrieval system