PATHWAY: ko00640 Help Entry ko00640                     Pathway                                 Name Propanoate metabolism Class Metabolism; Carbohydrate metabolism BRITE hierarchy Pathway map ko00640   Propanoate metabolism Module M00013   Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH:ko00640] M00741   Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ko00640] M00982   Methylcitrate cycle [PATH:ko00640] M00991   Dimethylsulfoniopropionate (DMSP) degradation, cleavage pathway, DMSP => acetyl-CoA [PATH:ko00640] M00992   Dimethylsulfoniopropionate (DMSP) degradation, cleavage pathway, DMSP => acrylate => acetyl-CoA [PATH:ko00640] M00993   Dimethylsulfoniopropionate (DMSP) degradation, cleavage pathway, DMSP => propionyl-CoA [PATH:ko00640] Other DBs GO:  0019541 Orthology K00005   gldA; glycerol dehydrogenase [EC:1.1.1.6] K00016   LDH; L-lactate dehydrogenase [EC:1.1.1.27] K00048   fucO; lactaldehyde reductase [EC:1.1.1.77] K00086   dhaT; 1,3-propanediol dehydrogenase [EC:1.1.1.202] K00140   mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] K00166   BCKDHA, bkdA1; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] K00167   BCKDHB, bkdA2; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] K00169   porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] K00170   porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] K00171   porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] K00172   porC, porG; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] K00189   vorG, porG; 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] K00232   E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6] K00248   ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] K00382   DLD, lpd, pdhD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] K00625   pta; phosphate acetyltransferase [EC:2.3.1.8] K00656   E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] K00822   E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18] K00823   puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] K00925   ackA; acetate kinase [EC:2.7.2.1] K00932   tdcD; propionate kinase [EC:2.7.2.15] K01026   pct; propionate CoA-transferase [EC:2.8.3.1] K01578   MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9] K01637   ICL, aceA; isocitrate/methylisocitrate lyase [EC:4.1.3.1 4.1.3.30] K01659   prpC; 2-methylcitrate synthase [EC:2.3.3.5] K01682   acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] K01692   paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17] K01699   pduC; propanediol dehydratase large subunit [EC:4.2.1.28] K01720   prpD; 2-methylcitrate dehydratase [EC:4.2.1.79] K01734   mgsA; methylglyoxal synthase [EC:4.2.3.3] K01782   fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] K01825   fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] K01847   MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] K01848   E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] K01849   E5.4.99.2B, mcmA2; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] K01895   ACSS1_2, acs; acetyl-CoA synthetase [EC:6.2.1.1] K01899   LSC1; succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] K01900   LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] K01902   sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] K01903   sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] K01905   acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] K01908   ACSS3, prpE; propionyl-CoA synthetase [EC:6.2.1.17] K01946   ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K01961   accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] K01962   accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] K01963   accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] K01964   K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] K01965   PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3] K01966   PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15] K02160   accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein K03416   E2.1.3.1-5S; methylmalonyl-CoA carboxyltransferase 5S subunit [EC:2.1.3.1] K03417   prpB; methylisocitrate lyase [EC:4.1.3.30] K05605   HIBCH; 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] K05606   MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] K07250   gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] K07511   ECHS1; enoyl-CoA hydratase [EC:4.2.1.17] K07514   EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] K07515   HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] K08325   yqhD; NADP-dependent alcohol dehydrogenase [EC:1.1.-.-] K09699   DBT, bkdB; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] K09788   prpF; 2-methylaconitate isomerase [EC:5.3.3.-] K11262   ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K11263   bccA, pccA, accA3; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14] K11264   scpB, mmcD; methylmalonyl-CoA decarboxylase [EC:4.1.1.-] K11381   bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] K13524   ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] K13788   pta; phosphate acetyltransferase [EC:2.3.1.8] K13919   pduD; propanediol dehydratase medium subunit [EC:4.2.1.28] K13920   pduE; propanediol dehydratase small subunit [EC:4.2.1.28] K13921   pduQ; 1-propanol dehydrogenase K13922   pduP; propionaldehyde dehydrogenase [EC:1.2.1.87] K13923   pduL; phosphate propanoyltransferase [EC:2.3.1.222] K14468   mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.2.1.75 1.1.1.298] K14729   FOX2; multifunctional beta-oxidation protein [EC:4.2.1.- 1.1.1.-] K15024   K15024; putative phosphotransacetylase [EC:2.3.1.8] K15036   K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] K15037   K15037; biotin carboxyl carrier protein K17489   E2.1.3.1-12S; methylmalonyl-CoA carboxyltransferase 12S subunit [EC:2.1.3.1] K17490   E2.1.3.1-1.3S; methylmalonyl-CoA carboxyltransferase 1.3S subunit [EC:2.1.3.1] K17741   GRE2; NADPH-dependent methylglyoxal reductase [EC:1.1.1.283] K18426   ECHDC1; ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.-] K18471   ydjG; methylglyoxal reductase [EC:1.1.1.-] K18472   accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] K19312   pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] K19697   pduW; propionate kinase [EC:2.7.2.15] K19745   acuI; acrylyl-CoA reductase (NADPH) [EC:1.3.1.-] K20143   acrC; acrylyl-CoA reductase (NADH) [EC:1.3.1.95] K20455   acnD; 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) [EC:4.2.1.117] K20626   lcdA; lactoyl-CoA dehydratase subunit alpha [EC:4.2.1.54] K20627   lcdB; lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54] K22214   scpC; propionyl-CoA:succinyl-CoA transferase [EC:2.8.3.27] K22224   acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] K22568   pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3] K23146   HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase K23257   yvgN; methylglyoxal/glyoxal reductase K24012   acdAB; acetate---CoA ligase (ADP-forming) K25571   pydD; beta-alanine---2-oxoglutarate transaminase K26355   ard; acrylate reductase K27094   accD5; propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit K27095   accE5, accE; acyl-CoA carboxylase epsilon subunit K27797   MCSA; 2-methylcitrate synthase K27802   acnA; aconitate hydratase A / 2-methylisocitrate dehydratase K28060   dddA; 3-hydroxypropionate dehydrogenase K28061   dddB; 3-hydroxypropionate dehydrogenase Compound C00024   Acetyl-CoA C00036   Oxaloacetate C00042   Succinate C00068   Thiamin diphosphate C00083   Malonyl-CoA C00091   Succinyl-CoA C00099   beta-Alanine C00100   Propanoyl-CoA C00109   2-Oxobutanoate C00111   Glycerone phosphate C00163   Propanoate C00186   (S)-Lactate C00222   3-Oxopropanoate C00424   (S)-Lactaldehyde C00479   Propanal C00511   Acrylic acid C00546   Methylglyoxal C00583   Propane-1,2-diol C00683   (S)-Methylmalonyl-CoA C00804   Propynoate C00827   Lactoyl-CoA C00894   Propenoyl-CoA C01013   3-Hydroxypropanoate C01213   (R)-Methylmalonyl-CoA C02170   Methylmalonate C02225   2-Methylcitrate C02335   beta-Alanyl-CoA C02876   Propanoyl phosphate C04225   (Z)-But-2-ene-1,2,3-tricarboxylate C04593   (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate C05235   Hydroxyacetone C05668   3-Hydroxypropionyl-CoA C05979   Propane-1-ol C05983   Propionyladenylate C05984   2-Hydroxybutanoic acid C05989   3-Oxopropionyl-CoA C06002   (S)-Methylmalonate semialdehyde C15972   Enzyme N6-(lipoyl)lysine C15973   Enzyme N6-(dihydrolipoyl)lysine C21017   2-(alpha-Hydroxypropyl)thiamine diphosphate C21018   Enzyme N6-(S-propyldihydrolipoyl)lysine C21250   2-Methyl-trans-aconitate Related pathway ko00010   Glycolysis / Gluconeogenesis ko00020   Citrate cycle (TCA cycle) ko00260   Glycine, serine and threonine metabolism ko00270   Cysteine and methionine metabolism ko00280   Valine, leucine and isoleucine degradation ko00410   beta-Alanine metabolism ko00620   Pyruvate metabolism ko00660   C5-Branched dibasic acid metabolism ko00770   Pantothenate and CoA biosynthesis

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