KEGG   PATHWAY: kpg00330
Entry
kpg00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella pneumoniae subsp. pneumoniae KPNIH32
Class
Metabolism; Amino acid metabolism
Pathway map
kpg00330  Arginine and proline metabolism
kpg00330

Module
kpg_M00015  Proline biosynthesis, glutamate => proline [PATH:kpg00330]
kpg_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kpg00330]
kpg_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kpg00330]
kpg_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:kpg00330]
kpg_M00970  Proline degradation, proline => glutamate [PATH:kpg00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella pneumoniae subsp. pneumoniae KPNIH32 [GN:kpg]
Gene
KPNIH32_15285  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
KPNIH32_07640  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPNIH32_15275  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPNIH32_25585  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPNIH32_23225  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
KPNIH32_23220  agmatinase [KO:K01480] [EC:3.5.3.11]
KPNIH32_23350  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
KPNIH32_04500  spermidine synthase [KO:K00797] [EC:2.5.1.16]
KPNIH32_04495  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
KPNIH32_24195  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
KPNIH32_14685  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
KPNIH32_12770  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
KPNIH32_21170  agmatinase [KO:K12255] [EC:3.5.3.7]
KPNIH32_10905  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
KPNIH32_12285  arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
KPNIH32_10915  succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
KPNIH32_12295  N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
KPNIH32_10900  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
KPNIH32_12280  argD; acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
KPNIH32_10910  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
KPNIH32_12290  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
KPNIH32_10920  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
KPNIH32_12300  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
KPNIH32_09840  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
KPNIH32_09820  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
KPNIH32_07085  FAD-dependent oxidoreductase [KO:K09471] [EC:1.4.3.-]
KPNIH32_09825  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
KPNIH32_09835  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
KPNIH32_05620  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
KPNIH32_09945  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
KPNIH32_05360  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
KPNIH32_05355  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
KPNIH32_09550  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kpg00020  Citrate cycle (TCA cycle)
kpg00220  Arginine biosynthesis
kpg00250  Alanine, aspartate and glutamate metabolism
kpg00260  Glycine, serine and threonine metabolism
kpg00270  Cysteine and methionine metabolism
kpg00310  Lysine degradation
kpg00410  beta-Alanine metabolism
kpg00470  D-Amino acid metabolism
kpg00480  Glutathione metabolism
kpg00630  Glyoxylate and dicarboxylate metabolism
kpg00650  Butanoate metabolism
kpg00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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