KEGG   PATHWAY: lil00230
Entry
lil00230                    Pathway                                
Name
Purine metabolism - Leptospira interrogans serovar Lai 56601
Class
Metabolism; Nucleotide metabolism
Pathway map
lil00230  Purine metabolism
lil00230

Module
lil_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:lil00230]
lil_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:lil00230]
lil_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:lil00230]
lil_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:lil00230]
Other DBs
GO: 0006163 0042278
Organism
Leptospira interrogans serovar Lai 56601 [GN:lil]
Gene
LA_3822  prsA; phosphoribosyl pyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
LA_4092  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
LA_3764  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
LA_2282  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
LA_4266  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
LA_1323  purL; phosphoribosylformylglycinamidine (FGAM) synthase [KO:K23269] [EC:6.3.5.3]
LA_3512  purS; phosphoribosylformylglycinamidine synthase [KO:K23264] [EC:6.3.5.3]
LA_3511  purL; phosphoribosylformylglycinamidine (FGAM) synthase [KO:K23265] [EC:6.3.5.3 3.5.1.2]
LA_2935  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
LA_1462  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
LA_1463  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
LA_3513  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
LA_3080  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
LA_2283  purH; PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
LB_176  apt; phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
LA_3874  surE; acid phosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
LA_0973  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
LA_2150  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
LA_4295  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
LA_1986  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
LA_4168  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
LA_3666  xanthosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
LA_2087  guaA; bifunctional GMP synthase/glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
LA_2598  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
LA_2360  nrdA; ribonucleotide reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
LA_2274  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
LA_3085  spoT; guanosine polyphosphate pyrophosphohydrolase/synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
LA_2761  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
LB_094  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LB_118  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_0027  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_1184  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_2536  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_2643  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_2834  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_2968  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_3234  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_3286  adenylate cyclase related protein [KO:K01768] [EC:4.6.1.1]
LA_3843  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_4008  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_0288  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_0565  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_0993  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_1070  cyaA; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
LA_1110  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
LA_0760  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
LA_4063  mazG; nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
LA_2044  hit; HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
LA_4219  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
LA_4220  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
lil00030  Pentose phosphate pathway
lil00220  Arginine biosynthesis
lil00250  Alanine, aspartate and glutamate metabolism
lil00260  Glycine, serine and threonine metabolism
lil00340  Histidine metabolism
lil00630  Glyoxylate and dicarboxylate metabolism
lil00730  Thiamine metabolism
lil00740  Riboflavin metabolism
lil00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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