KEGG   PATHWAY: llx00230
Entry
llx00230                    Pathway                                
Name
Purine metabolism - Lactococcus lactis subsp. lactis NCDO 2118
Class
Metabolism; Nucleotide metabolism
Pathway map
llx00230  Purine metabolism
llx00230

Module
llx_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:llx00230]
llx_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:llx00230]
Other DBs
GO: 0006163 0042278
Organism
Lactococcus lactis subsp. lactis NCDO 2118 [GN:llx]
Gene
NCDO2118_2002  ytfB; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NCDO2118_0950  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
NCDO2118_1977  prs3; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
NCDO2118_0827  prs1; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
NCDO2118_1548  purF; Amidophosphoribosyltransferase (ATase) [KO:K00764] [EC:2.4.2.14]
NCDO2118_1534  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
NCDO2118_1543  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
NCDO2118_1550  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
NCDO2118_1552  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
NCDO2118_1551  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
NCDO2118_1544  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
NCDO2118_1532  purK; Phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
NCDO2118_1533  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
NCDO2118_1553  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
NCDO2118_1743  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
NCDO2118_1538  purH; Bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NCDO2118_0630  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
NCDO2118_1096  nucA; 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
NCDO2118_0952  deoD; Purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
NCDO2118_0021  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NCDO2118_1539  hprT; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NCDO2118_0213  guaB; Inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
NCDO2118_1310  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
NCDO2118_1146  xpt; Xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
NCDO2118_1501  guaA; GMP synthase - glutamine-hydrolyzing [KO:K01951] [EC:6.3.5.2]
NCDO2118_1145  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
NCDO2118_2019  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
NCDO2118_1040  nrdE; Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
NCDO2118_1039  nrdF; Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
NCDO2118_0271  nrdD; Ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
NCDO2118_0073  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NCDO2118_0886  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
NCDO2118_0425  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
NCDO2118_2055  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
NCDO2118_0343  add; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
NCDO2118_0359  2,3-cyclic-nucleotide 2-phosphodiesterase / 3-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
NCDO2118_2187  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
NCDO2118_1798  arcC; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
NCDO2118_2140  arcC1; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
NCDO2118_2141  arcC2; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
llx00030  Pentose phosphate pathway
llx00220  Arginine biosynthesis
llx00250  Alanine, aspartate and glutamate metabolism
llx00260  Glycine, serine and threonine metabolism
llx00340  Histidine metabolism
llx00630  Glyoxylate and dicarboxylate metabolism
llx00730  Thiamine metabolism
llx00740  Riboflavin metabolism
llx00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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