KEGG   PATHWAY: mbk00630
Entry
mbk00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium tuberculosis variant bovis BCG Korea 1168P
Class
Metabolism; Carbohydrate metabolism
Pathway map
mbk00630  Glyoxylate and dicarboxylate metabolism
mbk00630

Module
mbk_M00012  Glyoxylate cycle [PATH:mbk00630]
mbk_M00621  Glycine cleavage system [PATH:mbk00630]
mbk_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mbk00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium tuberculosis variant bovis BCG Korea 1168P [GN:mbk]
Gene
K60_004930  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
K60_020080  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
K60_038040  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
K60_019230  malate synthase G [KO:K01638] [EC:2.3.3.9]
K60_013310  malate dehydrogenase mdh [KO:K00024] [EC:1.1.1.37]
K60_009500  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
K60_012170  Methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
K60_009570  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
K60_015820  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
K60_002650  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_009170  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_014220  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_011540  beta-ketoacyl CoA thiolase fadA3 [KO:K00626] [EC:2.3.1.9]
K60_019540  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_009770  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_036580  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_036840  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_036940  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K60_014210  4-hydroxyphenylpyruvate dioxygenase [KO:K05606] [EC:5.1.99.1]
K60_034150  acetyl-coenzyme A carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K60_034100  propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K60_034110  hypothetical protein [KO:K27095]
K60_023320  acetyl/propionyl-CoA carboxylase beta subunit AccD6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K60_016010  methylmalonyl-CoA mutase small subunit mutA [KO:K01847] [EC:5.4.99.2]
K60_016020  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
K60_023630  dehydrogenase [KO:K00104] [EC:1.1.99.14]
K60_019670  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
K60_029610  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
K60_023030  glutamine synthetase GLNA1 (glutamine synthase) (GS-I) [KO:K01915] [EC:6.3.1.2]
K60_023050  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
K60_000770  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K60_011780  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K60_019180  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
K60_022930  glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
K60_004880  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
K60_019120  glycine cleavage system protein H [KO:K02437]
K60_022870  hypothetical protein [KO:K00865] [EC:2.7.1.165]
K60_013400  alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K60_030720  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
K60_001320  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mbk00010  Glycolysis / Gluconeogenesis
mbk00020  Citrate cycle (TCA cycle)
mbk00030  Pentose phosphate pathway
mbk00053  Ascorbate and aldarate metabolism
mbk00071  Fatty acid degradation
mbk00230  Purine metabolism
mbk00250  Alanine, aspartate and glutamate metabolism
mbk00260  Glycine, serine and threonine metabolism
mbk00620  Pyruvate metabolism
mbk00710  Carbon fixation by Calvin cycle
mbk00750  Vitamin B6 metabolism
mbk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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