KEGG   PATHWAY: mbk00230
Entry
mbk00230                    Pathway                                
Name
Purine metabolism - Mycobacterium tuberculosis variant bovis BCG Korea 1168P
Class
Metabolism; Nucleotide metabolism
Pathway map
mbk00230  Purine metabolism
mbk00230

Module
mbk_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mbk00230]
mbk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mbk00230]
mbk_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mbk00230]
mbk_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mbk00230]
mbk_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mbk00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium tuberculosis variant bovis BCG Korea 1168P [GN:mbk]
Gene
K60_031840  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
K60_010890  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
K60_008620  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
K60_008250  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
K60_010240  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
K60_004080  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
K60_008570  phosphoribosylformylglycinamidine synthase II purL [KO:K23269] [EC:6.3.5.3]
K60_008420  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
K60_008430  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
K60_008630  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
K60_034060  phosphoribosylaminoimidazole carboxylase ATPase subunit purK [KO:K01589] [EC:6.3.4.18]
K60_034050  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
K60_008330  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
K60_008300  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
K60_010250  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
K60_026870  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
K60_034370  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
K60_022320  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K60_035300  nucleoside hydrolase IunH [KO:K01239] [EC:3.2.2.1]
K60_037560  hypoxanthine-guanine phosphoribosyltransferase hpt [KO:K00760] [EC:2.4.2.8]
K60_035480  inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
K60_035490  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
K60_025410  nucleoside diphosphate kinase ndkA [KO:K00940] [EC:2.7.4.6]
K60_014400  hypothetical protein [KO:K01519] [EC:3.6.1.66]
K60_035340  GMP synthase [KO:K01951] [EC:6.3.5.2]
K60_019290  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
K60_014920  guanylate kinase [KO:K00942] [EC:2.7.4.8]
K60_031640  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
K60_006040  ribonucleoside-diphosphate reductase large subunit NrdZ [KO:K00525] [EC:1.17.4.1]
K60_031610  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K60_002540  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K60_024390  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
K60_026860  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
K60_005240  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K60_010980  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K60_013550  adenylyl cyclase [KO:K01768] [EC:4.6.1.1]
K60_017080  membrane-anchored adenylyl cyclase Cya (ATP pyrophosphate-lyase) (adenylate cyclase) [KO:K01768] [EC:4.6.1.1]
K60_037780  transmembrane protein [KO:K01768] [EC:4.6.1.1]
K60_003770  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
K60_022840  carbohydrate kinase CbhK [KO:K00856] [EC:2.7.1.20]
K60_034450  adenosine deaminase add [KO:K01488] [EC:3.5.4.4]
K60_007810  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
K60_010930  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
K60_008590  hypothetical protein [KO:K03651] [EC:3.1.4.53]
K60_027180  hypothetical protein [KO:K19710] [EC:2.7.7.53]
K60_013790  bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.7.4 2.7.1.25]
K60_013780  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
K60_019360  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
K60_019350  urease subunit beta [KO:K01429] [EC:3.5.1.5]
K60_019340  urease gamma subunit ureA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mbk00030  Pentose phosphate pathway
mbk00220  Arginine biosynthesis
mbk00250  Alanine, aspartate and glutamate metabolism
mbk00260  Glycine, serine and threonine metabolism
mbk00340  Histidine metabolism
mbk00630  Glyoxylate and dicarboxylate metabolism
mbk00730  Thiamine metabolism
mbk00740  Riboflavin metabolism
mbk00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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