KEGG   PATHWAY: mesa00230
Entry
mesa00230                   Pathway                                
Name
Purine metabolism - Methanocaldococcus lauensis SG1
Class
Metabolism; Nucleotide metabolism
Pathway map
mesa00230  Purine metabolism
mesa00230

Module
mesa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mesa00230]
mesa_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mesa00230]
mesa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mesa00230]
mesa_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:mesa00230]
Other DBs
GO: 0006163 0042278
Organism
Methanocaldococcus lauensis SG1 [GN:mesa]
Gene
MLASG1_0035  [KO:K05873] [EC:4.6.1.1]
MLASG1_0047  [KO:K01519] [EC:3.6.1.66]
MLASG1_0067  [KO:K18931] [EC:2.4.2.57]
MLASG1_0103  purO; IMP cyclohydrolase [KO:K11176] [EC:3.5.4.10]
MLASG1_0143  [KO:K22026] [EC:2.7.1.73 2.7.1.213 2.7.1.-]
MLASG1_0278  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MLASG1_0279  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MLASG1_0299  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MLASG1_0404  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
MLASG1_0419  guaAA; GMP synthase [glutamine-hydrolyzing] subunit A [KO:K01951] [EC:6.3.5.2]
MLASG1_0545  ade; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
MLASG1_0552  purQ; Phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
MLASG1_0751  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [KO:K06863] [EC:6.3.4.23]
MLASG1_0864  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MLASG1_0865  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
MLASG1_0877  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MLASG1_0947  guaAB; GMP synthase [glutamine-hydrolyzing] subunit B [KO:K01951] [EC:6.3.5.2]
MLASG1_0965  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MLASG1_0984  hpt; Hypoxanthine/guanine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MLASG1_1036  [KO:K01529]
MLASG1_1196  purL; Phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
MLASG1_1197  ndk; multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
MLASG1_1228  [KO:K18532] [EC:2.7.4.3]
MLASG1_1388  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MLASG1_1458  adkA; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
MLASG1_1506  [KO:K21636] [EC:1.1.98.6]
MLASG1_1547  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MLASG1_1548  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MLASG1_1584  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mesa00030  Pentose phosphate pathway
mesa00220  Arginine biosynthesis
mesa00250  Alanine, aspartate and glutamate metabolism
mesa00260  Glycine, serine and threonine metabolism
mesa00340  Histidine metabolism
mesa00630  Glyoxylate and dicarboxylate metabolism
mesa00730  Thiamine metabolism
mesa00740  Riboflavin metabolism
mesa00790  Folate biosynthesis
KO pathway
ko00230   

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