KEGG   PATHWAY: mich00630
Entry
mich00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Micromonospora sp. HM134
Class
Metabolism; Carbohydrate metabolism
Pathway map
mich00630  Glyoxylate and dicarboxylate metabolism
mich00630

Module
mich_M00012  Glyoxylate cycle [PATH:mich00630]
mich_M00621  Glycine cleavage system [PATH:mich00630]
Other DBs
GO: 0046487 0043648
Organism
Micromonospora sp. HM134 [GN:mich]
Gene
FJK98_13710  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
FJK98_02020  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
FJK98_13715  malate synthase A [KO:K01638] [EC:2.3.3.9]
FJK98_28200  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FJK98_18055  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
FJK98_19845  citrate synthase [KO:K01647] [EC:2.3.3.1]
FJK98_02840  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
FJK98_22855  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
FJK98_20470  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
FJK98_26765  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FJK98_00930  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FJK98_04855  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FJK98_26770  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
FJK98_04440  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
FJK98_04530  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
FJK98_04355  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
FJK98_01275  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
FJK98_01270  cobalamin B12-binding domain-containing protein [KO:K01846] [EC:5.4.99.1]
FJK98_29885  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
FJK98_01540  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
FJK98_09220  catalase [KO:K03781] [EC:1.11.1.6]
FJK98_02760  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FJK98_07670  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FJK98_24460  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
FJK98_24530  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
FJK98_16520  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
FJK98_17615  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
FJK98_24360  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
FJK98_24375  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FJK98_17570  gcvH; glycine cleavage system protein GcvH [KO:K02437]
FJK98_24290  glycerate kinase [KO:K00865] [EC:2.7.1.165]
FJK98_16085  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
FJK98_27280  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
FJK98_17480  dehydrogenase [KO:K00123] [EC:1.17.1.9]
FJK98_17485  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
FJK98_17490  4Fe-4S dicluster domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mich00010  Glycolysis / Gluconeogenesis
mich00020  Citrate cycle (TCA cycle)
mich00030  Pentose phosphate pathway
mich00053  Ascorbate and aldarate metabolism
mich00071  Fatty acid degradation
mich00230  Purine metabolism
mich00250  Alanine, aspartate and glutamate metabolism
mich00260  Glycine, serine and threonine metabolism
mich00620  Pyruvate metabolism
mich00710  Carbon fixation by Calvin cycle
mich00750  Vitamin B6 metabolism
mich00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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