KEGG   PATHWAY: mmu00190
Entry
mmu00190                    Pathway                                
Name
Oxidative phosphorylation - Mus musculus (house mouse)
Class
Metabolism; Energy metabolism
Pathway map
mmu00190  Oxidative phosphorylation
mmu00190

Module
mmu_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:mmu00190]
mmu_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:mmu00190]
mmu_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:mmu00190]
mmu_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:mmu00190]
mmu_M00148  Succinate dehydrogenase (ubiquinone) [PATH:mmu00190]
mmu_M00151  Cytochrome bc1 complex respiratory unit [PATH:mmu00190]
mmu_M00152  Cytochrome bc1 complex [PATH:mmu00190]
mmu_M00154  Cytochrome c oxidase [PATH:mmu00190]
mmu_M00158  F-type ATPase, eukaryotes [PATH:mmu00190]
mmu_M00160  V-type ATPase, eukaryotes [PATH:mmu00190]
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
17716  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
17717  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
17718  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
17719  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
17720  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
17721  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
17722  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
227197  Ndufs1; NADH:ubiquinone oxidoreductase core subunit S1 [KO:K03934] [EC:7.1.1.2]
226646  Ndufs2; NADH:ubiquinone oxidoreductase core subunit S2 [KO:K03935] [EC:7.1.1.2]
68349  Ndufs3; NADH:ubiquinone oxidoreductase core subunit S3 [KO:K03936] [EC:7.1.1.2]
17993  Ndufs4; NADH:ubiquinone oxidoreductase core subunit S4 [KO:K03937]
595136  Ndufs5; NADH:ubiquinone oxidoreductase core subunit S5 [KO:K03938]
407785  Ndufs6; NADH:ubiquinone oxidoreductase core subunit S6 [KO:K03939]
623286  Ndufs6b; NADH:ubiquinone oxidoreductase subunit S6B [KO:K03939]
75406  Ndufs7; NADH:ubiquinone oxidoreductase core subunit S7 [KO:K03940] [EC:7.1.1.2]
225887  Ndufs8; NADH:ubiquinone oxidoreductase core subunit S8 [KO:K03941] [EC:7.1.1.2]
17995  Ndufv1; NADH:ubiquinone oxidoreductase core subunit V1 [KO:K03942] [EC:7.1.1.2]
72900  Ndufv2; NADH:ubiquinone oxidoreductase core subunit V2 [KO:K03943] [EC:7.1.1.2]
78330  Ndufv3; NADH:ubiquinone oxidoreductase core subunit V3 [KO:K03944]
54405  Ndufa1; NADH:ubiquinone oxidoreductase subunit A1 [KO:K03945]
17991  Ndufa2; NADH:ubiquinone oxidoreductase subunit A2 [KO:K03946]
66091  Ndufa3; NADH:ubiquinone oxidoreductase subunit A3 [KO:K03947]
17992  Ndufa4; Ndufa4, mitochondrial complex associated [KO:K03948]
407790  Ndufa4l2; Ndufa4, mitochondrial complex associated like 2 [KO:K03948]
68202  Ndufa5; NADH:ubiquinone oxidoreductase subunit A5 [KO:K03949]
100502727  Gm19340; predicted gene, 19340 [KO:K03949]
67130  Ndufa6; NADH:ubiquinone oxidoreductase subunit A6 [KO:K03950]
66416  Ndufa7; NADH:ubiquinone oxidoreductase subunit A7 [KO:K03951]
68375  Ndufa8; NADH:ubiquinone oxidoreductase subunit A8 [KO:K03952]
66108  Ndufa9; NADH:ubiquinone oxidoreductase subunit A9 [KO:K03953]
67273  Ndufa10; NADH:ubiquinone oxidoreductase subunit A10 [KO:K03954]
70316  Ndufab1; NADH:ubiquinone oxidoreductase subunit AB1 [KO:K03955]
102634451  Ndufab1-ps; NADH:ubiquinone oxidoreductase subunit AB1b [KO:K03955]
69875  Ndufa11; NADH:ubiquinone oxidoreductase subunit A11 [KO:K03956]
66414  Ndufa12; NADH:ubiquinone oxidoreductase subunit A12 [KO:K11352]
67184  Ndufa13; NADH:ubiquinone oxidoreductase subunit A13 [KO:K11353]
102631912  Ndufb1; NADH:ubiquinone oxidoreductase subunit B1 [KO:K03957]
68198  Ndufb2; NADH:ubiquinone oxidoreductase subunit B2 [KO:K03958]
66495  Ndufb3; NADH:ubiquinone oxidoreductase subunit B3 [KO:K03959]
68194  Ndufb4; NADH:ubiquinone oxidoreductase subunit B4 [KO:K03960]
100042503  Ndufb4b; NADH:ubiquinone oxidoreductase subunit B4B [KO:K03960]
100041273  Ndufb4c; NADH:ubiquinone oxidoreductase subunit B4C [KO:K03960]
66046  Ndufb5; NADH:ubiquinone oxidoreductase subunit B5 [KO:K03961]
230075  Ndufb6; NADH:ubiquinone oxidoreductase subunit B6 [KO:K03962]
66916  Ndufb7; NADH:ubiquinone oxidoreductase subunit B7 [KO:K03963]
67264  Ndufb8; NADH:ubiquinone oxidoreductase subunit B8 [KO:K03964]
66218  Ndufb9; NADH:ubiquinone oxidoreductase subunit B9 [KO:K03965]
68342  Ndufb10; NADH:ubiquinone oxidoreductase subunit B10 [KO:K03966]
104130  Ndufb11; NADH:ubiquinone oxidoreductase subunit B11 [KO:K11351]
66377  Ndufc1; NADH:ubiquinone oxidoreductase subunit C1 [KO:K03967]
68197  Ndufc2; NADH:ubiquinone oxidoreductase subunit C2 [KO:K03968]
66945  Sdha; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) [KO:K00234] [EC:1.3.5.1]
67680  Sdhb; succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [KO:K00235] [EC:1.3.5.1]
66052  Sdhc; succinate dehydrogenase complex, subunit C, integral membrane protein [KO:K00236]
66925  Sdhd; succinate dehydrogenase complex, subunit D, integral membrane protein [KO:K00237]
66694  Uqcrfs1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [KO:K00411] [EC:7.1.1.8]
17711  CYTB; cytochrome b [KO:K00412]
66445  Cyc1; cytochrome c-1 [KO:K00413]
22273  Uqcrc1; ubiquinol-cytochrome c reductase core protein 1 [KO:K00414]
67003  Uqcrc2; ubiquinol cytochrome c reductase core protein 2 [KO:K00415]
66576  Uqcrh; ubiquinol-cytochrome c reductase hinge protein [KO:K00416]
67530  Uqcrb; ubiquinol-cytochrome c reductase binding protein [KO:K00417]
22272  Uqcrq; ubiquinol-cytochrome c reductase, complex III subunit VII [KO:K00418]
66152  Uqcr10; ubiquinol-cytochrome c reductase, complex III subunit X [KO:K00419]
102633050  Gm6293; predicted pseudogene 6293 [KO:K00419]
66594  Uqcr11; ubiquinol-cytochrome c reductase, complex III subunit XI [KO:K00420]
70383  Cox10; heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 [KO:K02257] [EC:2.5.1.141]
17710  COX3; cytochrome c oxidase subunit III [KO:K02262]
17708  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
17709  COX2; cytochrome c oxidase subunit II [KO:K02261]
12857  Cox4i1; cytochrome c oxidase subunit 4I1 [KO:K02263]
84682  Cox4i2; cytochrome c oxidase subunit 4I2 [KO:K02263]
12858  Cox5a; cytochrome c oxidase subunit 5A [KO:K02264]
102633230  Gm11633; predicted gene 11633 [KO:K02264]
12859  Cox5b; cytochrome c oxidase subunit 5B [KO:K02265]
12861  Cox6a1; cytochrome c oxidase subunit 6A1 [KO:K02266]
12862  Cox6a2; cytochrome c oxidase subunit 6A2 [KO:K02266]
110323  Cox6b1; cytochrome c oxidase, subunit 6B1 [KO:K02267]
333182  Cox6b2; cytochrome c oxidase subunit 6B2 [KO:K02267]
12864  Cox6c; cytochrome c oxidase subunit 6C [KO:K02268]
12866  Cox7a2; cytochrome c oxidase subunit 7A2 [KO:K02270]
12865  Cox7a1; cytochrome c oxidase subunit 7A1 [KO:K02270]
20463  Cox7a2l; cytochrome c oxidase subunit 7A2 like [KO:K02270]
66142  Cox7b; cytochrome c oxidase subunit 7B [KO:K02271]
78174  Cox7b2; cytochrome c oxidase subunit 7B2 [KO:K02271]
12867  Cox7c; cytochrome c oxidase subunit 7C [KO:K02272]
12868  Cox8a; cytochrome c oxidase subunit 8A [KO:K02273]
12869  Cox8b; cytochrome c oxidase subunit 8B [KO:K02273]
75483  Cox8c; cytochrome c oxidase subunit 8C [KO:K02273]
69802  Cox11; cytochrome c oxidase assembly protein 11, copper chaperone [KO:K02258]
226139  Cox15; cytochrome c oxidase assembly protein 15 [KO:K02259] [EC:1.17.99.9]
12856  Cox17; cytochrome c oxidase assembly protein 17, copper chaperone [KO:K02260]
13063  Cycs; cytochrome c, somatic [KO:K08738]
13067  Cyct; cytochrome c, testis [KO:K08738]
11946  Atp5f1a; ATP synthase F1 subunit alpha [KO:K02132]
11947  Atp5f1b; ATP synthase F1 subunit beta [KO:K02133] [EC:7.1.2.2]
11949  Atp5f1c; ATP synthase F1 subunit gamma [KO:K02136]
66043  Atp5f1d; ATP synthase F1 subunit delta [KO:K02134]
67126  Atp5f1e; ATP synthase F1 subunit epsilon [KO:K02135]
28080  Atp5po; ATP synthase peripheral stalk subunit OSCP [KO:K02137]
17705  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
11950  Atp5pb; ATP synthase peripheral stalk-membrane subunit b [KO:K02127]
11951  Atp5mc1; ATP synthase membrane subunit c locus 1 [KO:K02128]
67942  Atp5mc2; ATP synthase membrane subunit c locus 2 [KO:K02128]
228033  Atp5mc3; ATP synthase membrane subunit c locus 3 [KO:K02128]
71679  Atp5pd; ATP synthase peripheral stalk subunit d [KO:K02138]
11958  Atp5me; ATP synthase membrane subunit e [KO:K02129]
57423  Atp5mf; ATP synthase membrane subunit f [KO:K02130]
27425  Atp5mg; ATP synthase membrane subunit g [KO:K02140]
11957  Atp5pf; ATP synthase peripheral stalk subunit F6 [KO:K02131]
17706  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
11964  Atp6v1a; ATPase, H+ transporting, lysosomal V1 subunit A [KO:K02145] [EC:7.1.2.2]
11966  Atp6v1b2; ATPase, H+ transporting, lysosomal V1 subunit B2 [KO:K02147]
110935  Atp6v1b1; ATPase, H+ transporting, lysosomal V1 subunit B1 [KO:K02147]
66335  Atp6v1c1; ATPase, H+ transporting, lysosomal V1 subunit C1 [KO:K02148]
68775  Atp6v1c2; ATPase, H+ transporting, lysosomal V1 subunit C2 [KO:K02148]
73834  Atp6v1d; ATPase, H+ transporting, lysosomal V1 subunit D [KO:K02149]
11973  Atp6v1e1; ATPase, H+ transporting, lysosomal V1 subunit E1 [KO:K02150]
74915  Atp6v1e2; ATPase, H+ transporting, lysosomal V1 subunit E2 [KO:K02150]
66144  Atp6v1f; ATPase, H+ transporting, lysosomal V1 subunit F [KO:K02151]
66237  Atp6v1g2; ATPase, H+ transporting, lysosomal V1 subunit G2 [KO:K02152]
66290  Atp6v1g1; ATPase, H+ transporting, lysosomal V1 subunit G1 [KO:K02152]
338375  Atp6v1g3; ATPase, H+ transporting, lysosomal V1 subunit G3 [KO:K02152]
108664  Atp6v1h; ATPase, H+ transporting, lysosomal V1 subunit H [KO:K02144]
11975  Atp6v0a1; ATPase, H+ transporting, lysosomal V0 subunit A1 [KO:K02154]
21871  Atp6v0a2; ATPase, H+ transporting, lysosomal V0 subunit A2 [KO:K02154]
27060  Tcirg1; T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 [KO:K02154]
140494  Atp6v0a4; ATPase, H+ transporting, lysosomal V0 subunit A4 [KO:K02154]
11984  Atp6v0c; ATPase, H+ transporting, lysosomal V0 subunit C [KO:K02155]
114143  Atp6v0b; ATPase, H+ transporting, lysosomal V0 subunit B [KO:K03661]
11972  Atp6v0d1; ATPase, H+ transporting, lysosomal V0 subunit D1 [KO:K02146]
242341  Atp6v0d2; ATPase, H+ transporting, lysosomal V0 subunit D2 [KO:K02146]
11974  Atp6v0e; ATPase, H+ transporting, lysosomal V0 subunit E [KO:K02153]
76252  Atp6v0e2; ATPase, H+ transporting, lysosomal V0 subunit E2 [KO:K02153]
54411  Atp6ap1; ATPase, H+ transporting, lysosomal accessory protein 1 [KO:K03662]
11944  Atp4a; ATPase, H+/K+ exchanging, gastric, alpha polypeptide [KO:K01542] [EC:7.2.2.19]
11945  Atp4b; ATPase, H+/K+ exchanging, beta polypeptide [KO:K01543] [EC:7.2.2.19]
192113  Atp12a; ATPase, H+/K+ transporting, nongastric, alpha polypeptide [KO:K01544] [EC:7.2.2.19]
67895  Ppa1; pyrophosphatase (inorganic) 1 [KO:K01507] [EC:3.6.1.1]
74776  Ppa2; pyrophosphatase (inorganic) 2 [KO:K01507] [EC:3.6.1.1]
76429  Lhpp; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

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