KEGG   PATHWAY: mul00630
Entry
mul00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium ulcerans
Class
Metabolism; Carbohydrate metabolism
Pathway map
mul00630  Glyoxylate and dicarboxylate metabolism
mul00630

Module
mul_M00012  Glyoxylate cycle [PATH:mul00630]
mul_M00621  Glycine cleavage system [PATH:mul00630]
mul_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mul00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium ulcerans [GN:mul]
Gene
MUL_4536  icl; isocitrate lyase Icl [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MUL_2943  aceAb; isocitrate lyase AceAb [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MUL_4241  acs; acetyl-coenzyme a synthetase Acs [KO:K01895] [EC:6.2.1.1]
MUL_3055  glcB; malate synthase G GlcB [KO:K01638] [EC:2.3.3.9]
MUL_4504  mdh; malate dehydrogenase Mdh [KO:K00024] [EC:1.1.1.37]
MUL_0255  gltA2; citrate synthase I GltA2 [KO:K01647] [EC:2.3.3.1]
MUL_0259  citA; citrate synthase II CitA [KO:K01647] [EC:2.3.3.1]
MUL_2494  gltA1; citrate synthase I GltA1 [KO:K01659] [EC:2.3.3.5]
MUL_1484  acn; aconitate hydratase Acn [KO:K27802] [EC:4.2.1.3 4.2.1.99]
MUL_4717  thiolase [KO:K00626] [EC:2.3.1.9]
MUL_3938  fadA4; acetyl-CoA acetyltransferase FadA4 [KO:K00626] [EC:2.3.1.9]
MUL_0296  fadA; acyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
MUL_4082  ltp3; lipid carrier protein or keto acyl-CoA thiolase Ltp3 [KO:K00626] [EC:2.3.1.9]
MUL_4107  fadA5; acetyl-CoA acetyltransferase FadA5 [KO:K00626] [EC:2.3.1.9]
MUL_1167  fadA2; acetyl-CoA acyltransferase FadA2 [KO:K00626] [EC:2.3.1.9]
MUL_0207  fadA3; beta-ketoacyl CoA thiolase FadA3 [KO:K00626] [EC:2.3.1.9]
MUL_4119  fadA6_1; acetyl-CoA acetyltransferase FadA6_1 [KO:K00626] [EC:2.3.1.9]
MUL_3008  conserved hypothetical protein [KO:K00626] [EC:2.3.1.9]
MUL_3939  gloA_1; glyoxalase, GloA_1 [KO:K05606] [EC:5.1.99.1]
MUL_2637  accA3; bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
MUL_2632  accD5; propionyl-CoA carboxylase beta chain 5 AccD5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MUL_2633  conserved protein [KO:K27095]
MUL_1302  accD6; acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MUL_1506  mutB; methylmalonyl-CoA mutase large subunit, MutB [KO:K01847] [EC:5.4.99.2]
MUL_1505  mutA; methylmalonyl-CoA mutase small subunit, MutA [KO:K01847] [EC:5.4.99.2]
MUL_0366  mcmA2b; methylmalonyl-CoA mutase alpha subunit, McmA2b [KO:K01849] [EC:5.4.99.2]
MUL_0367  mcmA2a; methylmalonyl-CoA mutase beta subunit, McmA2a [KO:K01848] [EC:5.4.99.2]
MUL_4485  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MUL_4291  katE; catalase KatE [KO:K03781] [EC:1.11.1.6]
MUL_3283  catalase [KO:K03781] [EC:1.11.1.6]
MUL_1320  conserved hypothetical protein [KO:K01091] [EC:3.1.3.18]
MUL_1335  glnA2; glutamine synthetase GlnA2 [KO:K01915] [EC:6.3.1.2]
MUL_1340  glnA1; glutamine synthetase GlnA1 [KO:K01915] [EC:6.3.1.2]
MUL_2782  conserved hypothetical protein [KO:K01915] [EC:6.3.1.2]
MUL_0188  glyA1; serine hydroxymethyltransferase 1 GlyA1 [KO:K00600] [EC:2.1.2.1]
MUL_4902  glyA2; serine hydroxymethyltransferase GlyA2 [KO:K00600] [EC:2.1.2.1]
MUL_3050  gcvB; glycine dehydrogenase GcvB [KO:K00281] [EC:1.4.4.2]
MUL_3571  gcvT; aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
MUL_2214  lpd; dihydrolipoamide dehydrogenase Lpd [KO:K00382] [EC:1.8.1.4]
MUL_4903  gcvH_1; glycine cleavage system H protein GcvH_1 [KO:K02437]
MUL_3045  gcvH; glycine cleavage system H protein GcvH [KO:K02437]
MUL_3562  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MUL_4500  kgd; alpha-ketoglutarate decarboxylase Kgd [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MUL_4804  oxcA; oxalyl-CoA decarboxylase OxcA [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mul00010  Glycolysis / Gluconeogenesis
mul00020  Citrate cycle (TCA cycle)
mul00030  Pentose phosphate pathway
mul00053  Ascorbate and aldarate metabolism
mul00071  Fatty acid degradation
mul00230  Purine metabolism
mul00250  Alanine, aspartate and glutamate metabolism
mul00260  Glycine, serine and threonine metabolism
mul00620  Pyruvate metabolism
mul00710  Carbon fixation by Calvin cycle
mul00750  Vitamin B6 metabolism
mul00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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