KEGG   PATHWAY: omc00330
Entry
omc00330                    Pathway                                
Name
Arginine and proline metabolism - Onychostoma macrolepis
Class
Metabolism; Amino acid metabolism
Pathway map
omc00330  Arginine and proline metabolism
omc00330

Module
omc_M00015  Proline biosynthesis, glutamate => proline [PATH:omc00330]
omc_M00047  Creatine pathway [PATH:omc00330]
omc_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:omc00330]
omc_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:omc00330]
omc_M00970  Proline degradation, proline => glutamate [PATH:omc00330]
omc_M00972  Proline metabolism [PATH:omc00330]
Other DBs
GO: 0006525 0006560
Organism
Onychostoma macrolepis [GN:omc]
Gene
131524423  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
131547274  LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial-like [KO:K00613] [EC:2.1.4.1]
131549858  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
131540943  ckmt2b; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
131547902  ckmt2a; creatine kinase, mitochondrial 2a (sarcomeric) [KO:K00933] [EC:2.7.3.2]
131533975  ckmt1; creatine kinase, mitochondrial 1 [KO:K00933] [EC:2.7.3.2]
131527075  ckbb; creatine kinase, brain b [KO:K00933] [EC:2.7.3.2]
131552708  ckba; creatine kinase, brain a isoform X1 [KO:K00933] [EC:2.7.3.2]
131554041  ckmb; creatine kinase, muscle b [KO:K27382] [EC:2.7.3.2]
131540189  ckma; creatine kinase, muscle a [KO:K27382] [EC:2.7.3.2]
131530327  zgc:172076 [KO:K27382] [EC:2.7.3.2]
131523614  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
131532009  srm; spermidine synthase isoform X1 [KO:K00797] [EC:2.5.1.16]
131528791  sms; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
131527721  amd1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
131533599  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
131548681  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
131545200  paox1; polyamine oxidase (exo-N4-amino) 1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
131541617  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
131520501  aldh3a2a; aldehyde dehydrogenase family 3 member A2a [KO:K00128] [EC:1.2.1.3]
131520502  aldh3a1; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
131537282  aldh16a1; aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
131528443  aldh3a2b; aldehyde dehydrogenase family 3 member A2b [KO:K00128] [EC:1.2.1.3]
131547733  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
131526279  aldh9a1b; 4-trimethylaminobutyraldehyde dehydrogenase B isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
131545954  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
131525934  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
131540983  sat2b; diamine acetyltransferase 2b [KO:K00657] [EC:2.3.1.57]
131541178  sat1a.2; diamine acetyltransferase 1a.2 [KO:K00657] [EC:2.3.1.57]
131541717  diamine acetyltransferase 1-like [KO:K00657] [EC:2.3.1.57]
131532932  sat1b; diamine acetyltransferase 1b [KO:K00657] [EC:2.3.1.57]
131544078  thialysine N-epsilon-acetyltransferase-like [KO:K00657] [EC:2.3.1.57]
131547965  si:ch211-127i16.2; LOW QUALITY PROTEIN: probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
131547269  mao; amine oxidase [flavin-containing] isoform X1 [KO:K00274] [EC:1.4.3.4]
131531777  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
131540926  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
131540748  nos2a; LOW QUALITY PROTEIN: nitric oxide synthase 2a, inducible [KO:K13241] [EC:1.14.13.39]
131520681  nos2b; nitric oxide synthase 2b, inducible [KO:K13241] [EC:1.14.13.39]
131550828  arg1; arginase-1 isoform X1 [KO:K01476] [EC:3.5.3.1]
131552118  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
131551401  oat; ornithine aminotransferase, mitochondrial isoform X1 [KO:K00819] [EC:2.6.1.13]
131549708  pycr1b; LOW QUALITY PROTEIN: pyrroline-5-carboxylate reductase 1b [KO:K00286] [EC:1.5.1.2]
131526750  pycr3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
131538094  pycr1a; pyrroline-5-carboxylate reductase 1a [KO:K00286] [EC:1.5.1.2]
131541565  prodhb; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
131529151  prodha; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
131549922  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
131551369  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
131532922  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
131523585  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b [KO:K00472] [EC:1.14.11.2]
131550824  p4ha1a; prolyl 4-hydroxylase subunit alpha-1a isoform X1 [KO:K00472] [EC:1.14.11.2]
131526846  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
131520914  p4ha3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
131528586  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
131528615  prolyl 4-hydroxylase subunit alpha-2-like [KO:K00472] [EC:1.14.11.2]
131551143  prodh2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
131552672  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
131546349  got1l1; putative aspartate aminotransferase, cytoplasmic 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
131524887  got2a; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
131544357  got2b; glutamic-oxaloacetic transaminase 2b, mitochondrial [KO:K14455] [EC:2.6.1.1]
131530559  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
131541059  D-amino-acid oxidase-like [KO:K00273] [EC:1.4.3.3]
131541060  D-amino-acid oxidase-like [KO:K00273] [EC:1.4.3.3]
131526884  trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
omc00020  Citrate cycle (TCA cycle)
omc00220  Arginine biosynthesis
omc00250  Alanine, aspartate and glutamate metabolism
omc00260  Glycine, serine and threonine metabolism
omc00270  Cysteine and methionine metabolism
omc00310  Lysine degradation
omc00410  beta-Alanine metabolism
omc00470  D-Amino acid metabolism
omc00480  Glutathione metabolism
omc00630  Glyoxylate and dicarboxylate metabolism
omc00650  Butanoate metabolism
omc00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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