KEGG   PATHWAY: paem00230
Entry
paem00230                   Pathway                                
Name
Purine metabolism - Pseudomonas aeruginosa MTB-1
Class
Metabolism; Nucleotide metabolism
Pathway map
paem00230  Purine metabolism
paem00230

Module
paem_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:paem00230]
paem_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:paem00230]
paem_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:paem00230]
paem_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:paem00230]
paem_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:paem00230]
paem_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:paem00230]
paem_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:paem00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas aeruginosa MTB-1 [GN:paem]
Gene
U769_27230  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
U769_28520  ADP-ribose diphosphatase [KO:K08312] [EC:3.6.1.-]
U769_29265  phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
U769_25565  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
U769_09360  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
U769_26635  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
U769_21065  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
U769_06120  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
U769_06060  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
U769_21060  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
U769_29810  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
U769_29815  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
U769_20750  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
U769_07310  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
U769_07315  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
U769_12025  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
U769_26630  purH; purine biosynthesis protein purH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
U769_18045  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
U769_06765  stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
U769_28525  haloacid dehalogenase [KO:K20881] [EC:3.1.3.-]
U769_17875  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
U769_24895  laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
U769_18415  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
U769_25435  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
U769_06025  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
U769_05835  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
U769_01995  nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
U769_29150  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
U769_18140  molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
U769_18145  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
U769_15975  aldehyde oxidase [KO:K11177] [EC:1.17.1.4]
U769_15980  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
U769_15985  (2Fe-2S)-binding protein [KO:K13483]
U769_06030  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
U769_00700  guanine deaminase [KO:K01487] [EC:3.5.4.3]
U769_18155  guanine deaminase [KO:K01487] [EC:3.5.4.3]
U769_12730  CMP deaminase [KO:K01487] [EC:3.5.4.3]
U769_29335  guanylate kinase [KO:K00942] [EC:2.7.4.8]
U769_19990  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
U769_30180  NrdJa [KO:K00525] [EC:1.17.4.1]
U769_19995  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
U769_16045  ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
U769_09710  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
U769_20135  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
U769_29345  bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
U769_28855  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
U769_21120  (p)ppGpp synthetase [KO:K00951] [EC:2.7.6.5]
U769_08825  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
U769_29015  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
U769_27065  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
U769_04985  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
U769_04270  LOG family protein ygdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
U769_00770  adenine deaminase [KO:K21053] [EC:3.5.4.2]
U769_06460  adenylate kinase [KO:K00939] [EC:2.7.4.3]
U769_21115  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
U769_27220  ser/threonine protein phosphatase [KO:K03651] [EC:3.1.4.53]
U769_03020  diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
U769_23900  adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
U769_18795  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
U769_23905  sulfate adenylyltransferase [KO:K00957] [EC:2.7.7.4]
U769_18170  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
U769_18180  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
U769_18175  chitin deacetylase [KO:K16842] [EC:3.5.2.5]
U769_18185  allantoicase [KO:K01477] [EC:3.5.3.4]
U769_20060  hypothetical protein [KO:K14977] [EC:3.5.3.26]
U769_18190  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
U769_26700  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
U769_26695  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
U769_26685  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
U769_28505  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
paem00030  Pentose phosphate pathway
paem00220  Arginine biosynthesis
paem00250  Alanine, aspartate and glutamate metabolism
paem00260  Glycine, serine and threonine metabolism
paem00340  Histidine metabolism
paem00630  Glyoxylate and dicarboxylate metabolism
paem00730  Thiamine metabolism
paem00740  Riboflavin metabolism
paem00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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