KEGG   PATHWAY: afj00230
Entry
afj00230                    Pathway                                
Name
Purine metabolism - Acidithiobacillus ferridurans
Class
Metabolism; Nucleotide metabolism
Pathway map
afj00230  Purine metabolism
afj00230

Module
afj_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:afj00230]
afj_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:afj00230]
afj_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:afj00230]
afj_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:afj00230]
afj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:afj00230]
afj_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:afj00230]
afj_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:afj00230]
Other DBs
GO: 0006163 0042278
Organism
Acidithiobacillus ferridurans [GN:afj]
Gene
AFERRID_03990  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
AFERRID_07160  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AFERRID_02110  Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AFERRID_03710  Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
AFERRID_28650  Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
AFERRID_30100  Formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
AFERRID_04260  Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
AFERRID_28660  Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
AFERRID_11320  N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
AFERRID_11330  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
AFERRID_04270  Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AFERRID_04280  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
AFERRID_03700  Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AFERRID_17680  Pur operon repressor [KO:K00759] [EC:2.4.2.7]
AFERRID_17030  5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AFERRID_16680  Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
AFERRID_10430  Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
AFERRID_25670  Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
AFERRID_28960  Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AFERRID_04120  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
AFERRID_20090  Caffeine dehydrogenase subunit beta [KO:K13479] [EC:1.17.1.4]
AFERRID_07450  4-hydroxybenzoyl-CoA reductase subunit alpha [KO:K11177] [EC:1.17.1.4]
AFERRID_07440  Putative xanthine dehydrogenase YagS FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
AFERRID_07460  Carbon monoxide dehydrogenase small chain [KO:K13483]
AFERRID_25680  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
AFERRID_04900  hypothetical protein [KO:K01951] [EC:6.3.5.2]
AFERRID_20040  Guanine deaminase [KO:K01487] [EC:3.5.4.3]
AFERRID_17880  Guanylate kinase [KO:K00942] [EC:2.7.4.8]
AFERRID_05940  Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
AFERRID_05950  Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
AFERRID_06730  Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
AFERRID_19670  Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
AFERRID_17900  Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
AFERRID_22650  Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AFERRID_28590  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
AFERRID_17590  Adenosine kinase [KO:K00856] [EC:2.7.1.20]
AFERRID_20050  Adenine deaminase [KO:K21053] [EC:3.5.4.2]
AFERRID_02700  hypothetical protein [KO:K09769] [EC:3.1.4.16]
AFERRID_10580  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
AFERRID_03120  Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
AFERRID_14150  Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
AFERRID_14140  Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
AFERRID_17670  putative bifunctional SAT/APS kinase [KO:K00958] [EC:2.7.7.4]
AFERRID_20100  Ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
afj00030  Pentose phosphate pathway
afj00220  Arginine biosynthesis
afj00250  Alanine, aspartate and glutamate metabolism
afj00260  Glycine, serine and threonine metabolism
afj00340  Histidine metabolism
afj00630  Glyoxylate and dicarboxylate metabolism
afj00730  Thiamine metabolism
afj00740  Riboflavin metabolism
afj00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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